Florence, SC Commercial real estate for sale

Industrial Buildings with Operational Capability

$350,000

40,000 SF

Industrial Buildings with Operational Capability

120 N Guerry St, Florence, SC 29501

Two standalone industrial buildings ideal for various commercial and industrial uses.

Two standalone industrial buildings offer flexibility for various uses.
Light Industrial zoning supports a wide range of commercial and industrial operations.
Brick building features approximately 20‑foot ceilings, three‑phase power, and three roll‑up doors.
Concrete block building includes 5,000 SF of interior space plus 2,000 SF of covered area and interior office space.
Ideal for fabrication, automotive uses, contractor operations, or storage.

Updated: Feb 23

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Versatile Commercial Property Near Downtown

$550,000

67,518 SF

Versatile Commercial Property Near Downtown

121 Lawson St, Florence, SC 29501

Office, showroom, and warehouse space near downtown Florence, SC.

Versatile commercial space with office, showroom, and warehouse areas under one roof.
Located less than one mile from Downtown Florence, SC.
Approximately 7,500 sq ft of heated and cooled office and showroom space with 9 offices and 3 showroom suites.
Zoned Light Industrial, allowing a wide range of permitted uses.
Multiple loading docks, delivery doors, and drive‑in doors for warehouse accessibility.

Updated: Feb 16

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$1,305,000

4,125 SF

Established Auto Body Business For Sale

Turn-key auto body business with equipment, client roster, and real estate.

803 Ranch Rd, Florence, SC 29506

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$396,396

0.91 Acres

Florence Commercial Land For Sale

0.91 acre commercial land parcel in Florence, South Carolina.

Presbyterian Rd, Florence, SC 29501

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$792,792

1.82 Acres

Florence Commercial Land For Sale

1.82 acre commercial land near I-95 in Florence, SC.

Tbd Presbyterian Rd, Florence, SC 29501

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$980,000

4.76 Acres

Prime Commercial Development Site

4.76-acre commercial land with high traffic exposure in Florence, SC.

917 S Cashua Dr, Florence, SC 29501

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Vacant Corner Lot For Sale

Vacant corner lot to be sold via online auction.

813 Chase St, Florence, SC 29501

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$1,500,000

7.27 Acres

Prime Commercial Land Near I-95

7.27 acres of commercial land near I-95 in Florence, SC.

3312 Meadors Rd, Florence, SC 29501

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$255,000

6.54 Acres

Unzoned Acreage in Florence, SC

6.54 acres of unzoned land with potential uses.

6.54 Acres-Tbd Alligator Rd, Florence, SC 29501

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$79,000

1,200 SF

Florence Commercial Building on Evans

Standalone building on Evans Street with redevelopment potential.

617 W Evans St, Florence, SC 29501

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$50,000

0.18 Acres

Commercial Lot Near National Cemetery

Unimproved commercial lot near Florence National Cemetery, zoned R-5A.

Tbd National Cemetery Rd, Florence, SC 29506

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$638,800

13,801 SF

Commercial Property on S Cashua Drive

Three buildings on three lots near Walmart in Florence, SC.

818 Delmae Dr, Florence, SC 29501

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$31,000

0.19 Acres

Commercial Lot on Darlington Street

Vacant commercial lot with frontage on Darlington Street, Florence, SC.

East Darlington St, Florence, SC 29506

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$31,000

0.19 Acres

Commercial Lot on Darlington Street

Commercial lot with frontage on East Darlington Street, Florence, SC.

East Darlington St, Florence, SC 29506

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$278,784

0.64 Acres

Florence Commercial Land For Sale

0.64 acre commercial land parcel in Florence, South Carolina.

Presbyterian Rd, Florence, SC 29501

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$1,500,000

4.02 Acres

Florence Commercial Lot For Sale

4.02 acre mixed-use lot with high visibility in Florence, SC.

1714 2Nd Loop Rd, Florence, SC 29501

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Vacant Land in Florence, SC

Vacant lot sold via online auction. Buyer responsible for due diligence.

813 N Dargan St, Florence, SC 29506

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$49,900

0.17 Acres

Florence Commercial Land For Sale

B-6 zoned property with commercial and redevelopment options.

720 S Barringer St, Florence, SC 29506

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$125,000

0.10 Acres

Corner Lot in Florence, SC

Commercial corner lot available in Florence, South Carolina.

360 N Dargan St, Florence, SC 29501

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$1,500,000

7,517 SF

Florence Office Building For Sale

Office building with 7,517 square feet of space in Florence.

1706 2Nd Loop Rd, Florence, SC 29501

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Former Convenience Store Investment Property

$125,000

2,400 SF

Former Convenience Store Investment Property

Fixer-upper retail property with 150' frontage, great investment potential.

1134 E Howe Springs Rd, Florence, SC 29505

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Retail Property Near Major Intersections

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38,000 SF

Retail Property Near Major Intersections

Retail property with high visibility and easy access.

2640 W Palmetto St, Florence, SC 29501

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Commercial Land Outparcels Available

Two outparcels available on Freedom Boulevard.

1701 Freedom Blvd, Florence, SC 29505

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2,202 SF

Wendy’s Restaurant in Florence, SC

Wendy’s restaurant for sale on high-traffic retail corridor.

624 S Irby St, Florence, SC 29501

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Florence, SC Commercial Real Estate Investment Opportunities Market Analysis

Explore 84 commercial real estate for sale in Florence, SC, showcased through 142 active listings on our real estate platform. These investment opportunities span a total of 23,809,896 square feet of properties for sale, with an estimated market value of $59,524,541.

Sale prices for business properties in Florence, SC start at $31,000, averaging $1,062,938, and reaching up to $16,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Florence, SC Commercial Real Estate for Sale

Industrial Buildings with Operational Capability

Two standalone industrial buildings ideal for various commercial and industrial uses.