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    Edwardsville, IL Commercial Real Estate for Lease

    51 results
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    Il, Edwardsville - Vandalia St.
    Contact for pricing

    Il, Edwardsville - Vandalia St.

    Workspaces, services and support to help you work better in Shelton

    101 Vandalia St, Edwardsville, IL 62025
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    Class A Office Space
    $2,300 / Mo

    Class A Office Space

    3 Club Centre Ct, Edwardsville, IL 62025

    Prime office space in Edwardsville, IL for lease.

    • Prime Class A office space in Club Centre location.
    • Located off State Route 157 with corner location.
    • Includes reception area, conference room, private offices, and open space.
    • Building equipped with elevator.
    • Shared kitchenette and handicapped accessible restrooms.
    Updated: Dec 10, 2025
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    Edwardsville Office Building For Lease
    $6,580 / Mo
    3,290 SF

    Edwardsville Office Building For Lease

    4 Sunset Hills Professional Ctr, Edwardsville, IL 62025

    3,290 SF office building in Sunset Hills Professional Centre.

    • 3,290 SF standalone office building
    • Located in the well‑established Sunset Hills Professional Centre
    • Prime location off IL‑157 in Edwardsville’s office/medical corridor
    • Main level features 7 private offices, conference room, and open bullpen
    • Finished break room and two restrooms in the lower level
    Updated: Oct 16, 2025
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    Retail Space in Edwardsville, IL
    Contact for pricing
    2,150 SF

    Retail Space in Edwardsville, IL

    Prime retail space with high visibility and ample parking.

    1502-1538 Troy Rd, Edwardsville, IL 62025
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    Distribution Center in Gateway Commerce
    $4 SF/Yr
    376,000 SF

    Distribution Center in Gateway Commerce

    Premier distribution park with interstate access and economic incentives.

    2601 Westway Dr, Edwardsville, IL
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    Edwardsville Warehouse with Conditioned Space
    $3 SF/Yr
    195,000 SF

    Edwardsville Warehouse with Conditioned Space

    195,000 SF warehouse with office and conditioned space available.

    21 Gateway Commerce Center Dr East, Edwardsville, IL 62025
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    Retail Space in Edwardsville Crossing
    Contact for pricing
    1,050 SF

    Retail Space in Edwardsville Crossing

    Retail space available in a shopping center with major retailers.

    6654 Edwardsville Crossing Dr, Edwardsville, IL
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    Retail Space in Edwardsville Crossing
    Contact for pricing
    1,200 SF

    Retail Space in Edwardsville Crossing

    Retail space available in a shopping center with major retailers.

    201 Edwardsville Crossing Dr, Edwardsville, IL
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    Edwardsville Office/Retail Suites Available
    Contact for pricing
    2,720 SF

    Edwardsville Office/Retail Suites Available

    Class A office/retail suites available in mixed-use development.

    1001-1010 Enclave Blvd, Edwardsville, IL
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    Downtown Edwardsville Office/Retail Space
    Contact for pricing
    1,800 SF

    Downtown Edwardsville Office/Retail Space

    1,800 SF space with frontage and visibility on Main Street.

    220 N Main St, Edwardsville, IL 62025
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    Downtown Edwardsville Office Space
    Contact for pricing
    4,624 SF

    Downtown Edwardsville Office Space

    Prime office space adjacent to Madison County courthouse.

    241 N Main St, Edwardsville, IL 62025
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    Downtown Edwardsville Retail/Office Space
    Contact for pricing
    1,029 SF

    Downtown Edwardsville Retail/Office Space

    Freestanding 1,029 SF retail/office space in downtown Edwardsville.

    501 N Main St, Edwardsville, IL 62025
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    Retail Space in Edwardsville Center
    Contact for pricing
    4,493 SF

    Retail Space in Edwardsville Center

    Retail-focused shopping center with parking and high visibility.

    2323 Plum St, Edwardsville, IL 62025
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    Retail Space Available For Lease
    Contact for pricing
    1,400 SF

    Retail Space Available For Lease

    Retail space available for lease in Edwardsville, Illinois.

    2100 Troy Rd, Edwardsville, IL 62025
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    Edwardsville Warehouse and Distribution Space
    Contact for pricing
    195,000 SF

    Edwardsville Warehouse and Distribution Space

    195,000 SF warehouse space available for lease in Edwardsville.

    7-21 Gateway Commerce Center Dr W, Edwardsville, IL 62025
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    Professional Office Space Available
    Contact for pricing
    950 SF

    Professional Office Space Available

    950 SF professional office space for lease.

    9 Jct Dr, Edwardsville, IL
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    7,682 SF Steel Warehouse
    Contact for pricing
    7,682 SF

    7,682 SF Steel Warehouse

    Warehouse with 2.88 acre lot and climate-controlled office space.

    5446 Chain Of Rocks Rd, Edwardsville, IL 62025
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    Edwardsville Warehouse with High Clearance
    Contact for pricing
    420,000 SF

    Edwardsville Warehouse with High Clearance

    420,000 SF warehouse featuring 40' clear height.

    29 Gateway Commerce Center Dr W, Edwardsville, IL 62025
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    New Warehouse Space Available
    Contact for pricing
    3,600 SF

    New Warehouse Space Available

    3,600 SF warehouse space for lease near I-255.

    5998 Redbud Ln, Edwardsville, IL 62025
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    Industrial Flex Space For Rent
    Contact for pricing
    2,400 SF

    Industrial Flex Space For Rent

    2,400 SF industrial flex space with drive-in doors.

    20 B Kettle Riv, Edwardsville, IL
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    Edwardsville Mixed-Use Retail/Office Space
    Contact for pricing
    1,932 SF

    Edwardsville Mixed-Use Retail/Office Space

    New construction mixed-use building with retail, office, and restaurant spaces.

    400 N Main St, Edwardsville, IL 62025
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    Edwardsville Executive Office Suite
    $24 SF/Yr
    7,611 SF

    Edwardsville Executive Office Suite

    Downtown Edwardsville, 1207 SF Available

    120 Main St, Edwardsville, IL 62025
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    Edwardsville Office Space For Lease
    $25 SF/Yr
    15,030 SF

    Edwardsville Office Space For Lease

    Prime Downtown Location, 1,000 SF Available

    100 Main St, Edwardsville, IL 62025
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    Edwardsville Office/Retail Space
    $25 SF/Yr
    12,104 SF

    Edwardsville Office/Retail Space

    Prime Downtown Edwardsville location, 2,520 SF available.

    228 Main St, Edwardsville, IL 62025
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    Edwardsville, IL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Edwardsville, IL with 113 listings featured on our commercial real estate exchange. The current inventory includes 77,077,067,760 square feet of properties with an estimated lease value of $497 /Mo.

    Estimated lease rates for Commercial real estate in Edwardsville, IL begin at $3 SF/Yr, with an average of $19 SF/Yr and extend to $30 SF/Yr.
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