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    Desoto, TX Commercial Real Estate for Sale

    67 results
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    DeSoto Office Building For Sale
    $465,000
    2,038 SF

    DeSoto Office Building For Sale

    580 N Hampton Rd, Desoto, TX 75115

    Standalone office building in DeSoto with high visibility.

    • Highly visible location on North Hampton Road in DeSoto.
    • Standalone 2,038 sq. ft. office building on nearly half an acre.
    • Features five private offices with closets, plus two additional rooms.
    • Includes a spacious walk‑in lobby, break room, and ample storage.
    • Modern interior with neutral color palette, ready for customization.
    Updated: Jan 31
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    Retail Property on Hampton Road
    $599,999
    0.40 Acres

    Retail Property on Hampton Road

    233 N Hampton Rd, Desoto, TX 75115

    Retail property in high-traffic area with flexible layout.

    • High‑traffic location on Hampton Road with excellent exposure.
    • Flexible layout suitable for various commercial uses.
    • Garage/storage area in the rear with loft space.
    • Additional parking available behind the building.
    • Located in a proven commercial corridor near established businesses (PNC Bank, Pizza Hut).
    Updated: Feb 23
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    DeSoto Commercial Property For Sale
    $525,000
    2,432 SF

    DeSoto Commercial Property For Sale

    Versatile commercial building ideal for office, medical, or retail use.

    701 N Hampton Rd, Desoto, TX 75115
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    DeSoto Flex Space Opportunity
    $3,650,000
    1.53 Acres

    DeSoto Flex Space Opportunity

    Flex space ideal for investors or owner-occupants with warehouse needs.

    400 E Centre Park Blvd, Desoto, TX 75115
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    Desoto Office Building For Sale
    $1,500,000
    13,565 SF

    Desoto Office Building For Sale

    13,565 SF office building in thriving Desoto, Texas.

    1701 N Hampton Rd, Desoto, TX 75115
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    DeSoto QSR Redevelopment Opportunity
    $617,000
    1,216 SF

    DeSoto QSR Redevelopment Opportunity

    Standalone QSR building in DeSoto's Hampton Road Redevelopment Corridor.

    122 S Hampton Rd, Desoto, TX 75115
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    DeSoto Retail Investment Opportunity
    $599,999
    3.34 Acres

    DeSoto Retail Investment Opportunity

    3+ acres zoned commercial retail with investment potential.

    121 Little John Dr, Desoto, TX 75115
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    DeSoto Commercial Revitalization Opportunity
    $999,000
    5.01 Acres

    DeSoto Commercial Revitalization Opportunity

    Income-producing property in area for commercial revitalization. Multiple potential uses.

    1012 E Wintergreen Rd, Desoto, TX 75115
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    DeSoto Commercial Land Opportunity
    $250,000
    0.52 Acres

    DeSoto Commercial Land Opportunity

    Prime commercial lot for office or medical development in DeSoto.

    1700 N Westmoreland Rd, Desoto, TX 75115
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    Prime Restaurant Building in DeSoto
    $795,000
    0.62 Acres

    Prime Restaurant Building in DeSoto

    Freestanding restaurant on 0.62 acres with high visibility.

    1109 E Pleasant Run Rd, Desoto, TX 75115
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    Commercial Lot in DeSoto, TX
    $120,000
    0.35 Acres

    Commercial Lot in DeSoto, TX

    Commercial lot for sale, great location for building.

    607 Parkdale Ln, Desoto, TX 75115
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    Commercial Lot in DeSoto, TX
    $120,000
    0.28 Acres

    Commercial Lot in DeSoto, TX

    Commercial lot for sale, great location for building.

    619 Franklin St, Desoto, TX 75115
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    Commercial Lot in DeSoto, TX
    $120,000
    0.28 Acres

    Commercial Lot in DeSoto, TX

    Commercial lot for sale, great location for building.

    623 Franklin St, Desoto, TX 75115
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    Commercial Land in DeSoto, TX
    $99,999
    0.33 Acres

    Commercial Land in DeSoto, TX

    Vacant commercial lot in a growing area with development potential.

    1213 Lyndon Ave, Desoto, TX 75115
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    Updated Medical Office Condo
    $631,680
    2,688 SF

    Updated Medical Office Condo

    2,688 SF medical office near Charlton Methodist Hospital.

    2727 Bolton Boone Dr, Desoto, TX 75115
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    DeSoto Church, Office, or School
    $2,950,000
    19,386 SF

    DeSoto Church, Office, or School

    19,386 SF building suitable for church, office, or school.

    2100 N Hampton Rd, Desoto, TX 75115
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    Commercial Pad Site For Sale
    $732,000
    1 SF

    Commercial Pad Site For Sale

    1.68-acre commercial pad site on W. Belt Line Road.

    1116 W Belt Line Rd, Desoto, TX 75115
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    Development Site with Highway Frontage
    Contact for pricing

    Development Site with Highway Frontage

    Large development site with frontage on I-35E in DeSoto, TX.

    513-515 N Interstate 35 E, Desoto, TX 75115
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    Commercial Land Near I-20, I-35E
    Contact for pricing
    1 SF

    Commercial Land Near I-20, I-35E

    Commercial land with excellent access to major highways.

    1531 N Hampton Rd, Desoto, TX 75115
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    Prime Retail Site in DeSoto
    Contact for pricing
    12,000 SF

    Prime Retail Site in DeSoto

    4.77 AC site ideal for retail development or ground lease.

    100 S Elerson Rd, Desoto, TX 75115
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    DeSoto Retail Zoned Land
    $2,800,000
    10 SF

    DeSoto Retail Zoned Land

    10.99 acres of commercially zoned land in DeSoto, Texas.

    1514 N Hampton Rd, Desoto, TX 75115
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    DeSoto Land Ready For Development
    Contact for pricing

    DeSoto Land Ready For Development

    Land primed for development with high visibility and easy access.

    S Hampton Rd & E Parkerville Rd, Desoto, TX
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    DeSoto Warehouse with Office Space
    $2,115,000
    22,500 SF

    DeSoto Warehouse with Office Space

    22,500 SF warehouse featuring offices and ample parking.

    1101 S Hampton Rd, Desoto, TX 75115
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    Desoto Retail Development Opportunity
    Contact for pricing

    Desoto Retail Development Opportunity

    13.7 acres for retail development along Interstate 35.

    300 E S I 35, Desoto, TX
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    Desoto, TX Commercial Real Estate Investment Opportunities Market Analysis

    Explore 36 commercial real estate for sale in Desoto, TX, showcased through 67 active listings on our real estate platform. These investment opportunities span a total of 1,214,888 square feet of properties for sale, with an estimated market value of $16,170,775.

    Sale prices for business properties in Desoto, TX start at $109,777, averaging $898,376, and reaching up to $3,650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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