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Medical Office Space with Open Layout
For Lease
$12,580/Mo

6635 E 21st Street, Indianapolis, IN 46219

Commercial Lease, Indianapolis, IN

Space Size7,548 SF
Lot Size1.20 Acres
Days on Market48

Property Features for 6635 E 21st Street

General Information

Property type Commercial Lease
Property subtype Office
Zoning C-1
Elementary school district MSD Warren Township
Middle school district MSD Warren Township
High school district MSD Warren Township
Directions GPS Friendly
Subdivision 4905 - Marion - Warren
Standard status Active
APN 490735116002000774
Lot size 1.20 Acres

Taxes and HOA fees

Tax Year 2025
Tax Description Pt W1/2 Ne1/4 S35 T16 R4 Beg 177.94' E Of Nw Core 154.89' S 263.05' W 154.89' N 263.05' To Beg.935 Ac
Legal Description Pt W1/2 Ne1/4 S35 T16 R4 Beg 177.94' E Of Nw Core 154.89' S 263.05' W 154.89' N 263.05' To Beg.935 Ac

Building Details

Floors in Building 1
Listing Agency: Keller Williams Indy Metro Partners · Keller Williams Realty
Listed By: Shelly Johnson · License #RB14043056
Added: Jul 15 Changed: Aug 28 Last Checked: Aug 31 at 10:06AM
MLS# 22114094

Copyright © 2026 Broker Listing Cooperative®. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

Investment Insights

Based on property information with market context.

This C-1 medical office property offers an ADA-accessible configuration with three private offices, four restrooms, a conference room, break area, waiting space, and a large central room. The open area can support a range of layouts, including treatment, classroom, worship, activity, showroom, or collaborative functions. Multiple entrances provide separate access points for staff, clients, and visitors, and the lease structure is NN.

Recent property improvements include a new roof, water heater, eight gas furnaces, AC units, motion-sensored flood lighting, LED fixtures, and a resurfaced parking lot. The 1.2-acre site includes two parking lots with nearly 50 spaces. Located in Indianapolis, the property is suited to medical, professional, community, religious, or daycare-related occupancy as supported by the existing configuration.

Key Highlights

  • 1.2‑acre medical office property with C‑1 zoning
  • ADA‑accessible layout with three private offices and four restrooms
  • Large open room adaptable for treatment, classroom, worship, activity, or collaborative use

Property Analytics

Current Use

Dr. Megan O'bryan Physician Fiducial Business Centers, ... Consultant RCG Indianapolis Medical Clinic Meliyah Harris Counselor Samantha Saxman Physician

Suggested Use

Top Pick Real Estate Agency Law Firm Dental Office Electrical Service Garden Center Kitchen & Bath Showroom

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type
$3.00 /SF/Yr
CAM

Location Intelligence

Trade Area within ½ mile

552
Businesses Nearby
Under-served
Demand for This Use

Demographics for 46219, IN

36,556
Population
17,028
Households
2.1
Avg Household Size
38
Median Age
26%
College-Educated
86%
High-School Grad
13.0 sq mi
ZIP Area
2,812
Density / Sq Mi
$57,811
Median Household Income
$38,995
Median Earnings
$991
Median Rent
$177,000
Median Home Value

Market

Lease Benchmarks for Indianapolis, IN

$19.19 /SF/Yr
Avg Asking Price
$16.98–$22.5 /SF/Yr
Price Range
9,697 SF
Avg Space Size

This space is priced 4% above the average of $19.19 /SF/Yr.

Vacancy Rate% for Office in Indianapolis, IN

17.4% 2019
17.8% 2020
19.1% 2021
19.3% 2022
22.2% 2023
22.8% 2024
21.4% 2025
Rey
Questions? Ask Rey
Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.

Frequently Asked Questions

What type of property is this?
Medical Office Space - ADA-accessible commercial space with private offices, multiple entrances, and substantial parking across two lots.
Where is this medical office space located?
The property is located at 6635 E 21st Street Indianapolis, IN.
What is the lease rate?
The lease rate is $12,580/Mo.
What are key features of this property?
This property features: 1.2‑acre medical office property with C‑1 zoning; ADA‑accessible layout with three private offices and four restrooms; Large open room adaptable for treatment, classroom, worship, activity, or collaborative use
More about this property
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