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Downtown Main Street Medical Office
For Lease
$27 SF/Yr

649 Main Street, Waltham, MA 02451

Renovated two-story suite with ADA-compliant restrooms, private treatment/offices, and separate rear access for flexible healthcare use.

Space SizeContact for details
Days on Market50

Property Features for 649 Main Street

General Information

Standard status Active
Property subtype Commercial

Taxes and HOA fees

Annual Taxes $11,665

Amenities

Shingle Roof

Building Details

Year Built 1910
Stories 2
Listing Agency: Lamacchia Realty, Inc.
Listed By: Suzanna Krmzian · License #449589928
Source: Corcoran
Added: Jul 2 Changed: Aug 20 Last Checked: Aug 20 at 5:00AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Lamacchia Realty, Inc.

Investment Insights

Based on property information with market context.

This two-story commercial building has been recently renovated and is set up with an open floor plan supported by expansive storefront windows for strong natural light. The interior configuration includes multiple private offices or treatment rooms, along with an updated ADA-compliant restroom. A rear service area and separate rear access provide operational flexibility. The space is designed to accommodate a range of professional and service uses, including retail, office, medical, wellness, showroom, creative, or other professional applications.

The property is positioned on busy Main Street in the heart of downtown Waltham, offering visibility to passing traffic. It is located among established businesses, restaurants, and retail shops, with public transportation nearby and access to major commuter routes.

For an owner-user or an operating tenant, the combination of renovated finishes, storefront presence, and dedicated treatment or office rooms can support day-to-day patient or client services while maintaining privacy within the plan. The presence of a rear service area and separate entrance can also help with workflows that benefit from back-of-house access.

Key Highlights

  • 3,890 SF two‑story commercial building with an open floor plan and expansive storefront windows.
  • Recently renovated interior with multiple private offices or treatment rooms.
  • Updated ADA‑compliant restroom(s) included.

Property Analytics

Current Use

Waltham Check Cashing ... Bank

Suggested Use

Top Pick Pet Grooming Service Tattoo & Piercing Shop Butcher Nursing Home (Bike/Boat/Book/etc) Store Bed & Breakfast

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type
$4.05 /SF/Yr
CAM

Location Intelligence

Trade Area within ½ mile

2,290
Businesses Nearby

Demographics for 02451, MA

17,953
Population
7,852
Households
2.3
Avg Household Size
39
Median Age
55%
College-Educated
93%
High-School Grad
5.3 sq mi
ZIP Area
3,387
Density / Sq Mi
$119,509
Median Household Income
$66,318
Median Earnings
$2,537
Median Rent
$709,200
Median Home Value

Market

Vacancy Rate% for Office in Northeast region

13.1% 2019
15.4% 2020
17.6% 2021
19.1% 2022
20.2% 2023
20.9% 2024
19.9% 2025
Rey
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Frequently Asked Questions

What type of property is this?
Office building - Renovated two-story suite with ADA-compliant restrooms, private treatment/offices, and separate rear access for flexible healthcare use.
Where is this office building located?
The property is located at 649 Main Street Waltham, MA.
What is the lease rate?
The lease rate is $27 SF/Yr.
What are key features of this property?
This property features: 3,890 SF two‑story commercial building with an open floor plan and expansive storefront windows.; Recently renovated interior with multiple private offices or treatment rooms.; Updated ADA‑compliant restroom(s) included.
More about this property
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