Spaces For Lease

at 591 Camino De La Reina Contact us

Tower 591 $3.25/SF/Mo

Floor

2

Size

2,659 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, 30 Days

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

1

Size

3,683 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, 60 Days

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

7

Size

3,655 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, 60 Days

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.50/SF/Mo

Floor

12

Size

801 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Suites 1200, 1210, 1216 & 1217 are contiguous for up to 10,766 SF - Tower 591 is... a twelve-story 183,000 SF, Class A office building located in the heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

10

Size

2,608 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

11

Size

2,888 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

11

Size

3,737 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

12

Size

1,279 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

12

Size

3,613 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

2

Size

1,821 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

2

Size

5,166 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

4

Size

3,426 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

4

Size

6,244 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

5

Size

1,149 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Tower 591 $3.25/SF/Mo

Floor

5

Size

1,667 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

5

Size

7,134 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

7

Size

2,837 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

8

Size

3,039 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

8

Size

5,955 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

9

Size

2,156 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, Now

Sublease

No

- Tower 591 is a twelve-story 183,000 SF, Class A office building located in the... heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

Tower 591 $3.25/SF/Mo

Floor

12

Size

5,073 SF

Type

OFFICE

Lease Type

PLUS_ELECTRIC

Availability

AVAILABLE, On Available Date

Sublease

No

- Suites 1200, 1210, 1216 & 1217 are contiguous for up to 10,766 SF - Tower 591 is... a twelve-story 183,000 SF, Class A office building located in the heart of Mission Valley. - Offering rare and high visibility building-top signage from Highway 163 and Interstate 8, the centrally located building is just minutes away from Downtown San Diego and the San Diego International Airport. - Tower 591 provides an easy commute with access to public transportation and high end amenities all within walking distance. - Experience the convenience of on-site amenities that include a modern exterior featuring outdoor lounge seating areas among scenic landscaping, a new contemporary cafe adjoining a fresh lobby, and updated fitness center to attract top talent—elevate your workplace at Tower 591. - Easy Access to I-8 and Hwy 163 - Abundant amenities: walk to shopping malls & restaurants - Parking covered with EV charging - Trolley stop at Fashion Valley mall

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Contact us

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Listing Agency: JLL | San Diego r***@jll.com Show Phone

Listed By: Richard Gonor · License #1142178

Source: Moodyscre

Added: Mar 14, 2025 Changed: Aug 8 Last Checked: Aug 8 at 12:27PM

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Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of JLL | San Diego

Investment Insights

Based on property information with market context.

Tower 591 is a twelve-story, 183,000 square foot, Class A office building situated in Mission Valley. The property offers high visibility building-top signage opportunities from Highway 163 and Interstate 8. Its central location provides convenient access to Downtown San Diego and the San Diego International Airport. The building is accessible via public transportation and is within walking distance of various amenities. On-site amenities include a modern exterior with outdoor lounge seating areas set among landscaping, a contemporary cafe adjoining the lobby, and an updated fitness center. Covered parking with EV charging stations is available. The trolley stop at Fashion Valley mall is nearby, and there is convenient access to shopping malls and restaurants.

Key Highlights

• High visibility building‑top signage from Highway 163 and Interstate 8.
• Class A office building in a central Mission Valley location, minutes from Downtown San Diego and the San Diego International Airport.
• Easy access to I‑8 and Hwy 163.

Property Analytics

Property Profile

Current Use

PNC Mortgage Loan Service Tommy Potts - Mutual ... Loan Service DeVries Corporate Formation Tax Preparation Satori World Medical Medical Clinic Kramer Shelley C Physician

Suggested Use

Top Pick Building Supply Big Box & Wholesale Store Dental Office Auto Repair Shop Auto Parts Store HVAC Service

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)

Lease Type

Location Intelligence

Trade Area within ½ mile

2,998

Businesses Nearby

Explore this area Business Placement

Market

Vacancy Rate% for Office in San Diego, CA

12% 2019

15.6% 2020

14% 2021

13.3% 2022

14.5% 2023

14.6% 2024

14.6% 2025

Questions? Ask Rey

Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.

What type of property is this? Where is this office buildings located? What is the lease rate? Find similar properties ... What are key features of this property?

Ask Rey about this property ...

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Frequently Asked Questions

What type of property is this?

Office building - Class A office building in the heart of Mission Valley.

Where is this office building located?

The property is located at 591 Camino De La Reina San Diego, CA.

What are key features of this property?

This property features: High visibility building‑top signage from Highway 163 and Interstate 8.; Class A office building in a central Mission Valley location, minutes from Downtown San Diego and the San Diego International Airport.; Easy access to I‑8 and Hwy 163.