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    Frederick, MD Commercial Real Estate for Sale

    53 results
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    Frederick Office Suite For Sale
    $419,999

    Frederick Office Suite For Sale

    6550 MERCANTILE Drive E unit: 105, Frederick, MD 21703

    Street-level office suite with tax benefits and modern design.

    • Significantly lower tax burden due to location outside Frederick City limits.
    • Strategic location in Frederick County with easy access to I‑270, I‑70, and Route 15.
    • Functional 1,520 sq ft layout with reception area, private offices, and flexible open space.
    • Suitable for professional or medical use with ADA‑compliant accessibility.
    • Abundance of natural light creating a comfortable environment.
    Updated: Mar 2
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    Frederick Medical/Office Condo For Sale
    $624,999

    Frederick Medical/Office Condo For Sale

    100 TUSCANNY #5, Frederick, MD 21702

    Professional medical/office condo in Frederick, ideal for owner-occupants or investors.

    • Prime location in the heart of Frederick, offering strong visibility and convenient access to major commuter routes, downtown, and Frederick Health facilities.
    • Functional layout designed for medical/professional use, including multiple exam/office rooms, reception/waiting area, and private workspaces.
    • Huge basement with high ceilings, two rear exits, and a utility sink, providing extensive storage and expansion potential.
    • Two bathrooms: one full bath with a shower and one half bath.
    • Well‑maintained suite in an established medical/professional complex with ample parking and a well‑managed association.
    Updated: Jan 2
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    Downtown Frederick Office/Medical Space
    $643,500

    Downtown Frederick Office/Medical Space

    974 SF office/medical space in historic downtown Frederick.

    241 E 4TH Street unit: 204A, Frederick, MD 21701
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    Frederick Office/Medical Building For Sale
    $3,250,000
    1.03 Acres

    Frederick Office/Medical Building For Sale

    10,600 SF office/medical building with onsite parking and natural light.

    195 THOMAS JOHNSON Drive, Frederick, MD 21702
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    Downtown Frederick Office/Medical Space
    $789,900

    Downtown Frederick Office/Medical Space

    2,848 SF office/medical space in historic downtown Frederick.

    241 E 4TH Street unit: 105, Frederick, MD 21701
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    Land in Frederick, Maryland
    $595,000
    4.75 Acres

    Land in Frederick, Maryland

    4.75 acre land parcel suitable for storage or warehouse development.

    WINCHESTER Boulevard, Frederick, MD 21703
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    Industrial Land in Frederick, MD
    $499,000
    2.61 Acres

    Industrial Land in Frederick, MD

    2.61 acre industrial lot with development and income potential.

    4060 STANFORD Court, Frederick, MD 21703
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    Downtown Frederick Office Space
    $631,250
    2,525 SF

    Downtown Frederick Office Space

    Unique office space in historic building with modern amenities.

    241 E 4th St #206, Frederick, MD 21701
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    Leased Mixed-Use Frederick Property
    $1,500,000
    0.05 Acres

    Leased Mixed-Use Frederick Property

    Income-producing property in a desirable, walkable downtown location.

    23-25-27 S MARKET ST, Frederick, MD 21701
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    Freestanding Office/Medical Building For Sale
    $3,250,000
    10,600 SF

    Freestanding Office/Medical Building For Sale

    10,600 SF office/medical building with parking and natural light.

    195 Thomas Johnson Dr, Frederick, MD 21702
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    Downtown Frederick Commercial Opportunity
    $545,000
    0.10 Acres

    Downtown Frederick Commercial Opportunity

    Prime commercial property in downtown Frederick with versatile zoning.

    325 W 7th St, Frederick, MD 21701
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    Versatile Commercial Building Near Interstates
    $1,800,000
    6,000 SF

    Versatile Commercial Building Near Interstates

    6,000 sq ft commercial building suitable for industrial or flex uses.

    4603 Wedgewood Blvd, Frederick, MD 21703
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    Frederick Office Space For Rent
    $585,000
    1,013 SF

    Frederick Office Space For Rent

    Office space for rent in Frederick, Maryland.

    50 Carroll Creek Way, Frederick, MD
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    Medical Office Condominium in Frederick
    $900,000
    3,087 SF

    Medical Office Condominium in Frederick

    Turnkey 3,087 SF medical office condo in Frederick, MD.

    6550 Mercantile Dr E, Frederick, MD 21703
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    Frederick Mixed-Use Redevelopment Opportunity
    $2,600,000
    36,000 SF

    Frederick Mixed-Use Redevelopment Opportunity

    Mixed-use property in downtown Frederick with redevelopment potential.

    257 E 6TH STREET, Frederick, MD 21701
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    Frederick County Industrial Land Parcel
    $499,000
    2.61 Acres

    Frederick County Industrial Land Parcel

    Prime industrial lot with flexible zoning and excellent regional access.

    4060 Stanford Ct, Frederick, MD 21703
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    Commercial Property with School Lease
    $2,977,000
    0.60 Acres

    Commercial Property with School Lease

    Commercial property for sale, currently leased to a Montessori school.

    211 DILL AVENUE, Frederick, MD 21701
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    Commercial/Industrial Lot For Sale
    $639,900
    1.31 Acres

    Commercial/Industrial Lot For Sale

    Highly visible lot zoned for light industrial use.

    94 Wormans Mill Ct, Frederick, MD
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    Frederick Commercial Property For Sale
    $515,000
    0.29 Acres

    Frederick Commercial Property For Sale

    Two-unit commercial property with M2 zoning in Frederick, Maryland.

    804-6 E South St, Frederick, MD 21701
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    Frederick Mixed-Use Property For Sale
    $439,000

    Frederick Mixed-Use Property For Sale

    Mixed-use property with commercial potential in a vibrant Frederick location.

    431 Patrick St, Frederick, MD 21701
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    35 Acres of Land, Frederick
    $299,900
    35.85 Acres

    35 Acres of Land, Frederick

    Two parcels totaling 35+/- acres in Frederick, Maryland.

    35+/- ACRES OFF BENNIE DUNCAN ROAD, Frederick, MD 21701
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    Church Building For Sale
    $1,500,000
    1.20 Acres

    Church Building For Sale

    Church building available for purchase.

    8325 Yellow Springs Rd, Frederick, MD 21702
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    Versatile Commercial Property For Sale
    $2,250,000
    0.92 Acres

    Versatile Commercial Property For Sale

    Spacious property with showroom, warehouse, and excellent accessibility.

    6905 Baltimore National Pike, Frederick, MD 21702
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    Frederick Commercial Property For Sale
    $495,000

    Frederick Commercial Property For Sale

    Two units with M2 zoning, potential for various uses.

    804-6 E South St, Frederick, MD 21701
    View details

    Frederick, MD Commercial Real Estate Investment Opportunities Market Analysis

    Explore 53 commercial real estate for sale in Frederick, MD, showcased through 53 active listings on our real estate platform. These investment opportunities span a total of 2,687,652 square feet of properties for sale, with an estimated market value of $28,302,100.

    Sale prices for business properties in Frederick, MD start at $299,900, averaging $1,572,338, and reaching up to $5,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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