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    Main Street Retail Opportunity Title is generated by Realmo AI

    5363 & 5365 Main Street, Williamsville, NY 14221

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    For Lease
    $21 SF/Yr $14,875/Mo (calc)

    Retail spaces and ground lease opportunity available on Main Street.

    Type:Retail
    Property size:
    8,500 SF
    Added:
    Nov 21, 2025
    Days on Market:
    181
    Last Refresh:
    Apr 5 at 8:59 pm

    Property Features for 5363 & 5365 Main Street

    General Information

    Standard status
    Active
    Size
    8,500 SF
    Property subtype
    Retail

    Building Details

    Year Built
    1957

    Spaces For Lease

    at 5363 & 5365 Main Street Contact us

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    Listing Contact
    Stephen Hunt

    Listing agent Stephen Hunt License #10301203321

    Listing office Hunt Commercial - Buffalo

    Listing date Nov 21, 2025

    Source Huntcommercial

    Displayed information is deemed reliable but is not guaranteed and should be independently verified.

    All listing content including descriptions, pricing, images are the copyrighted material of Hunt Commercial - Buffalo

    HighLights

    • Prime location on Main Street, near a new recreation park.
    • High traffic area, just five blocks from I‑290 access.
    • AltYou gym space (approximately 1,550 sf) available now, lease expiring October 31, 2025.
    • Up to 2,900 sf available for ground lease/build‑to‑suit.
    • Adjacent to established businesses including Qamaria Cafe and Rustic Buffalo.
    • Rental rate: $21 per sf NNN for the AltYou space, with 3% annual increases.

    Overview

    Located at 5363 and 5365 Main Street, this property presents several retail opportunities. Currently, Qamaria Cafe, a Yemeni coffee franchise, occupies a 2,400 square foot space, and Rustic Buffalo, an artisan general store, is located in a 1,263 square foot free-standing building. A 1,550 square foot gym, AltYou, is available at 5363 Main, with a lease term ending October 31, 2025. The rent for this space is $21 per square foot NNN, with 3% annual base rent increases. Additionally, a ground lease or build-to-suit option is available for up to 2,900 square feet on the south/rear of 5365 Main. A sketch is available showing a possible building placement on the parcel. The former Monro Muffler location at 5365 Main, approximately 2,900 square feet, is under lease subject to construction approval contingencies. The properties are situated just west of South Long Street and north of the Village of Williamsville recreation park, and five blocks east of the I-290/Main access and exit.
    Property Profile Insight Report Location Intelligence

    Current Use by Public Records

    altYou Gym & Fitness Center Community Testing Services Medical Laboratory

    Suggested Use

    Restaurant Real Estate Agency Law Firm Building Supply Spa & Massage Center Dental Office Big Box & Wholesale Store Auto Repair Shop Hair Salon Nail Salon

    Zoning and permitted uses should be independently verified with local authorities.

    Location Insight

    • Map
    • Local Demand
    City
    Williamsville
    County
    Erie
    State
    New York
    Longitude
    -78.7532
    Latitude
    42.9611

    FAQs

    What type of property is this?
    Retail space - Retail spaces and ground lease opportunity available on Main Street.
    Where is this retail space located?
    The property is located at 5363 & 5365 Main Street Williamsville, NY.
    What is the lease rate?
    The lease rate is $21 SF/Yr.
    What are key features of this property?
    This property features: Prime location on Main Street, near a new recreation park.; High traffic area, just five blocks from I‑290 access.; AltYou gym space (approximately 1,550 sf) available now, lease expiring October 31, 2025.
    More about this property
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