Advertise
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Turn-Key Office Suite Title is generated by Realmo AI

    450 Siemers Drive, Cape Girardeau, MO 63701

    View on Map
    Claim this Listing
    For Lease
    $5,642/Mo $10 SF/Yr (calc)

    COMMERCIAL - Cape Girardeau, MO

    Property size:
    6,770 SF
    Added:
    Nov 14, 2025
    Days on Market:
    231
    Last Refresh:
    Jul 3 at 7:06 am

    Property Features for 450 Siemers Drive

    General Information

    Property type
    Commercial Lease
    Property subtype
    Other
    Parking features
    Driveway
    Standard status
    Active
    APN
    20-300-00-01-00300-0000
    Size
    6,770 SF

    Taxes and HOA fees

    Tax Year
    2022
    Tax Annual Amount
    20933

    Utilities

    Utilities
    Cable Available
    Sewer type
    Public Sewer
    Heating system
    Forced Air, Natural Gas, Solar (Heating)
    Cooling system
    Central Air, Electric
    Water source
    Public

    Building Details

    Year built
    1991
    Floors in Building
    2

    We can help!

    Contact an agent
    Jacob Fish

    Listing agent Jacob Fish License #2010013545

    Listing office Edge Realty 2511 Independence Suite 100, Cape Girardeau, MO

    Listing date Nov 14, 2025

    MLS# 23066863

    Copyright © 2026 Mid America Regional Information Systems, Inc. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

    HighLights

    • Office suite with business park frontage on Hwy/Interstate
    • Built in 1991
    • Heating: forced air with natural gas and solar (heating)
    • Cooling: central air and electric
    • Utilities: cable available
    • Water and sewer: public water and public sewer

    Overview

    This turn-key office suite is presented as ready for immediate occupancy, positioned to support day-to-day business operations from the outset. The offering is designed as a dedicated office space within a commercial setting, with visibility-focused placement that is intended to serve both staff and visiting clients.

    The property is located at 450 Siemers Drive in a business park environment, with frontage along the highway/interstate corridor. That access and prominence are aligned with office users who benefit from being easy to find and straightforward for customers to reach.

    For prospective tenants, this space fits well for an office user seeking a turn-key setup rather than a longer buildout timeline. The combination of an office suite configuration and high-visibility placement along a major roadway can support a range of professional services and client-facing operations, while keeping day-to-day logistics simple within the business park setting.
    Property Profile Location Intelligence

    Current Use by Public Records

    CARSTAR Russom's Cape ... Auto Repair Shop

    Suggested Use

    Kitchen & Bath Showroom Food Market HVAC Service Grocery & Convenience Store Car Rental Facility (Bike/Boat/Book/etc) Store Daycare Center Veterinary Clinic Tech Support Center Shopping Center & Mall

    Zoning and permitted uses should be independently verified with local authorities.

    Location Insight

    • Map
    • Local Demand
    City
    Cape Girardeau
    County
    Cape Girardeau
    State
    Missouri
    Longitude
    -89.576846
    Latitude
    37.292747

    Nearby Similar for Lease

    • $1,958/Mo

      Updated Second-Floor Office Suite

      A secure second-floor suite with seven private offices, open area, and new finishes, leased with utilities included.
      2027 Broadway Street, Cape Girardeau, MO 63701
      View Details
    • $2,500/Mo
      2,937 SF

      Renovated Office and Storefront Building

      Renovated space with new HVAC and building systems, offering flexible office and personal-services layouts on a busy downtown corridor.
      230 N Sprigg Street, Cape Girardeau, MO 63701
      View Details
    • $18 SF/Yr
      3,000 SF

      Flexible Restaurant/Retail/Office Suite

      Versatile suites with existing restaurant infrastructure, positioned across from Towers Hall for high student traffic.
      820 N Sprigg St - Suites 3-4, Cape Girardeau, MO 63701
      View Details
    • $8,707/Mo
      3,483 SF

      Retail Building with Drive-Through Window

      Drive-through retail building with off-street paved parking on C2-zoned land, adjacent to major retailers.
      5 S Kingshighway, Cape Girardeau, MO 63703
      View Details
    • $850/Mo
      275 SF

      Remodeled Office Space with Amenities

      Centrally located office space with modern finishes and included amenities.
      1427 Thomas Dr, Cape Girardeau, MO 63701
      View Details
    • $850/Mo
      279 SF

      Remodeled Office Space with Amenities

      Centrally located office space with modern finishes and included amenities.
      1427 Thomas Dr, Cape Girardeau, MO 63701
      View Details
    • $1,500/Mo

      Flex Space with Off-Street Parking

      Flexible 1,172 SF flex space in an M-1 district, suited for day care, office, or professional service use.
      213 Clark Street, Cape Girardeau, MO 63701
      View Details
    • $2,600/Mo
      1,250 SF

      Second-Floor Office Suite

      Second-floor office suite with reception, private office, conference space, and an open area for flexible work setups.
      2b-301 Broadway St, Cape Girardeau, MO
      View Details
    • $8,558/Mo
      13,694 SF

      Downtown Office Building For Lease

      13,694 SF office building in historic downtown Cape Girardeau.
      18 N. Main, Cape Girardeau, MO 63701
      View Details
    • $1,100/Mo
      1,218 SF

      Professional Office Building For Rent

      1,218 SF professional office building in good location.
      720 Forest Ave, Cape Girardeau, MO 63701
      View Details
    • $3,000/Mo
      5,100 SF

      Cape Girardeau Warehouse Space Available

      Versatile warehouse space with high ceilings and ample parking.
      45 N Broadview St - Middle, Cape Girardeau, MO 63701
      View Details
    • $6,000/Mo
      9,600 SF

      Versatile Warehouse Space Available

      9600 sf warehouse with high ceilings, shared loading dock.
      45 N Broadview St - Front, Cape Girardeau, MO 63701
      View Details

    FAQs

    What type of property is this?
    Office units - Turn-key office suite in a business park with highway and interstate frontage for strong day-to-day customer visibility.
    Where is this office units located?
    The property is located at 450 Siemers Drive Cape Girardeau, MO.
    What is the lease rate?
    The lease rate is $5,642 /Mo.
    What are key features of this property?
    This property features: Office suite with business park frontage on Hwy/Interstate; Built in 1991; Heating: forced air with natural gas and solar (heating)
    (573) 335-8111
    We can help!
    Contact an agent
    Jacob Fish
    Real Estate License ID: 2010013545
    Request Owner's contact information
    Message sent successfully
    Error
    If you are the owner or broker of this property and would like to edit or remove this listing please send a message to web site administrator.
    Message sent successfully
    Error
    Email to Your Friends
    Link copied to clipboard
    Separate multiple addresses with a comma
    Message sent successfully
    Error
    More about this property
    Thanks! Your message was sent.
    Error! Your message wasn't sent.
    Please enter your name
    Please enter email
    Please enter the email in the correct format
    Please enter phone
    Please enter the number in the correct format
    Please enter message
    Thank You

    You are Unsubscribed From Notifications

    Thank You for Inquiry
    450 Siemers Drive, Cape Girardeau, MO 63701
    letter with green check mark
    Check your email
    We sent you the
    agent's contact details. yellow underline
    Can't find it?
    Please check your junk/spam folder.
    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!