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Cambridge Office Space for Lease
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450 Kendall Street, Cambridge, MA 02142

10,342 SF office space available in East Cambridge.

Space SizeContact for details
Days on Market266

Property Features for 450 Kendall Street

General Information

Standard status Active
Property subtype Office
Listing Agency: CBRE | Boston
Listed By: Eric Smith
Source: Cbre
Added: Nov 22, 2025 Changed: Aug 8 Last Checked: Aug 8 at 4:56AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE | Boston

Investment Insights

Based on property information with market context.

Available for lease is 10,342 square feet of office space located on the fifth floor of 450 Kendall Street in Cambridge, Massachusetts. The property is situated in the East Cambridge Life Science & Technology hub and offers convenient access to I-93. Its location provides close proximity to the Kendall Square MBTA Red Line Station and the EZ Ride Shuttle Bus. The surrounding area features a variety of amenities, including dining options, fitness centers, cinemas, and craft breweries.

Key Highlights

  • Located in the East Cambridge Life Science & Technology hub
  • 10,342 SF of office space available
  • Excellent access to I‑93

Property Analytics

Current Use

Eli Lilly Factory Glass House Restaurant Semma Therapeutics, Inc. Corporate Office MPM Factory MPM Capital Venture Capital Company

Suggested Use

Top Pick Building Supply Auto Repair Shop Big Box & Wholesale Store Auto Parts Store Kitchen & Bath Showroom HVAC Service

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

4,486
Businesses Nearby

Demographics for 02142, MA

4,499
Population
2,445
Households
1.8
Avg Household Size
32
Median Age
91%
College-Educated
100%
High-School Grad
0.3 sq mi
ZIP Area
14,997
Density / Sq Mi
$168,788
Median Household Income
$82,157
Median Earnings
$3,501
Median Rent
$1,726,900
Median Home Value

Market

Lease Benchmarks for Cambridge, MA

$41.67 /SF/Yr
Avg Asking Price
$4.71–$70.87 /SF/Yr
Price Range
9,718 SF
Avg Space Size

Vacancy Rate% for Office in Northeast region

13.1% 2019
15.4% 2020
17.6% 2021
19.1% 2022
20.2% 2023
20.9% 2024
19.9% 2025
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Frequently Asked Questions

What type of property is this?
Office units - 10,342 SF office space available in East Cambridge.
Where is this office units located?
The property is located at 450 Kendall Street Cambridge, MA.
What are key features of this property?
This property features: Located in the East Cambridge Life Science & Technology hub; 10,342 SF of office space available; Excellent access to I‑93
More about this property
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