Search
Denver Office Space Available
For Lease
$32 SF/Yr

4100 East Mississippi Avenue, Denver, CO 80246

Office space available for lease in Denver, Colorado.

Space SizeContact for details
Days on Market274

Property Features for 4100 East Mississippi Avenue

General Information

Standard status Active
Property subtype Office
Listing Agency: CBRE | Denver
Listed By: Blake Holcomb
Source: Cbre
Added: Nov 22, 2025 Changed: Aug 8 Last Checked: May 19 at 8:53PM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of CBRE | Denver

Investment Insights

Based on property information with market context.

Available for lease is an office space encompassing 35,561 square feet. The property is located at 4100 East Mississippi Avenue, Denver, CO, 80246. The asking lease rate is $29 per square foot.

Key Highlights

  • Office space available for lease
  • Located in Denver, Colorado

Property Analytics

Current Use

Kal Commercial Flooring General Contractor Centerre Construction Inc Construction Company VA Rocky Mountain ... Veterans Affairs Department Colorado Patents Law Firm Montgomery Amatuzio Chase ... Law Firm

Suggested Use

Top Pick Florist Butcher Electrical Service (Bike/Boat/Book/etc) Store Auto Parts Store Clothing & Fashion Store

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type
$4.80 /SF/Yr
CAM

Location Intelligence

Trade Area within ½ mile

2,692
Businesses Nearby

Demographics for 80246, CO

13,265
Population
8,148
Households
1.6
Avg Household Size
32
Median Age
59%
College-Educated
96%
High-School Grad
1.7 sq mi
ZIP Area
7,803
Density / Sq Mi
$66,503
Median Household Income
$47,870
Median Earnings
$1,661
Median Rent
$659,700
Median Home Value

Market

Lease Benchmarks for Denver, CO

$28.53 /SF/Yr
Avg Asking Price
$1.69–$95.23 /SF/Yr
Price Range
9,253 SF
Avg Space Size

This space is priced 12% above the average of $28.53 /SF/Yr.

Vacancy Rate% for Office in Denver, CO

14.5% 2019
17.4% 2020
19.3% 2021
21.8% 2022
23% 2023
25% 2024
26.3% 2025
Rey
Questions? Ask Rey
Realmo’s AI knows this listing — price, zoning, demand, history. Ask anything.

Frequently Asked Questions

What type of property is this?
Office units - Office space available for lease in Denver, Colorado.
Where is this office units located?
The property is located at 4100 East Mississippi Avenue Denver, CO.
What is the lease rate?
The lease rate is $32 SF/Yr.
What are key features of this property?
This property features: Office space available for lease; Located in Denver, Colorado
More about this property
Thanks! Your message was sent.
Error! Your message wasn't sent.
Please enter your name
Please enter email
Please enter the email in the correct format
Please enter phone
Please enter the number in the correct format
Please enter message