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    Historic Office Landmark Reimagined Title is generated by Realmo AI

    350 Camino De La Reina, San Diego, CA 92108

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    Renovated historic office landmark with large, flexible workspaces designed for today’s workforce needs.

    Type:Office
    Added:
    Jun 2, 2026
    Days on Market:
    5
    Last Refresh:
    Jun 6 at 3:29 am

    Property Features for 350 Camino De La Reina

    General Information

    Standard status
    Active
    Property subtype
    Office

    Spaces For Lease

    at 350 Camino De La Reina Contact us

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    Listing Contact
    Derek Hulse
    Derek Hulse

    Listing agent Derek Hulse License #CA 01329963

    Listing office Cushman & Wakefield - San Diego, California

    Listing date Jun 2, 2026

    Source Crexi

    Displayed information is deemed reliable but is not guaranteed and should be independently verified.

    All listing content including descriptions, pricing, images are the copyrighted material of Cushman & Wakefield - San Diego, California

    HighLights

    • Former site of the San Diego Union‑Tribune, an iconic historic landmark
    • Printing press operations ceased in 2016
    • Renovated historic office landmark reimagined for modern workplace needs
    • Large, flexible workspaces designed to accommodate changing company needs

    Overview

    AMP&RSAND is a historic office landmark that was formerly the site of the San Diego Union-Tribune. The property has been progressively redesigned for modern workplace requirements, while retaining its historic core. The building is positioned as a workplace environment intended to support a company’s changing needs through large, agile office spaces.

    The building is located at 350 Camino De La Reina in San Diego, CA 92108. As a well-known local landmark tied to the former printing operation, the property offers a distinctive identity for tenants seeking character alongside modern updates.

    For prospective tenants, AMP&RSAND’s emphasis on large, adaptable spaces can support teams that need room to organize work areas efficiently and potentially adjust over time. The property’s redesign approach focuses on creating a work setting that goes beyond a traditional office routine, aligning with organizations looking for a contemporary yet authentic workplace within a landmark building.
    Location Intelligence

    Current Use by Public Records

    HED Architect Chosen Foods LLC Big Box & Wholesale Store BREAK: All-day Cafe ... Cafe & Coffee Shop NextWave Holdco LLC Telecommunications Service Nexurn Digital (Bike/Boat/Book/etc) Store

    Suggested Use

    Restaurant Real Estate Agency Law Firm Building Supply Dental Office Spa & Massage Center Big Box & Wholesale Store Auto Repair Shop Hair Salon Nail Salon

    Zoning and permitted uses should be independently verified with local authorities.

    Location Insight

    • Map
    • Local Demand
    City
    San Diego
    County
    San Diego
    State
    California
    Longitude
    -117.1654575
    Latitude
    32.7641985

    FAQs

    What type of property is this?
    Office building - Renovated historic office landmark with large, flexible workspaces designed for today’s workforce needs.
    Where is this office building located?
    The property is located at 350 Camino De La Reina San Diego, CA.
    What are key features of this property?
    This property features: Former site of the San Diego Union‑Tribune, an iconic historic landmark; Printing press operations ceased in 2016; Renovated historic office landmark reimagined for modern workplace needs
    (858) 334-4005 Call to check price and availability
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