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Mixed-Use Building with Medical Space

2290 Main Street, Buffalo, NY 14214

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For Sale

$399,000

COMMERCIAL - Buffalo, NY

Property size:

4,620 SF

Lot size:

0.13 Acres

Price / SF:

$86/SF

HighLights

Mixed‑use property with 1,976 SF first‑floor medical/office/retail space plus option to divide into two units
Second‑floor 1,344 SF 2‑bedroom apartment; upper unit is rented
Law firm lease on the lower commercial space and approx. $3,300/month total income reported
500 SF reinforced concrete vault with 16‑foot ceilings for secured storage or specialty use
Exterior updates include an 8‑year‑old tear‑off roof, vinyl siding, and newer windows
Rear paved parking area for up to six vehicles; security buzz‑in system and central air

We can help!

Listing Contact

Thejan Kodituwakku

For Sale

$399,000

COMMERCIAL - Buffalo, NY

Property size:

4,620 SF

Lot size:

0.13 Acres

Price / SF:

$86/SF

Added:: Feb 27, 2026
Days on Market:: 109
Last Refresh:: Jun 16 at 10:06 pm

Property Features for 2290 Main Street

General Information

Property type: Commercial Sale
Property subtype: Other
Zoning: N-3C
Rooms: Basement
Parking: 6
Standard status: Active
APN: 140200-089-500-0003-010-000
Size: 4,620 SF
Lot size: 0.13 Acres

Taxes and HOA fees

Tax Annual Amount: 5972

Utilities

Sewer type: Public Sewer
Heating system: Hot Water(Heating), Forced Air, Natural Gas
Cooling system: Central Air
Water source: Public

Building Details

Year built: 1950
Floors in Building: 2
Building materials: Brick, Frame
Roof type: Asphalt

We can help!

Listing Contact

Thejan Kodituwakku

Listing agent Thejan Kodituwakku License #10401342241

Listing office Keller Williams Realty WNY 5500 Main St. Ste. 108, Williamsville, NY

Listing date Feb 27, 2026

MLS# B1658782

Copyright © 2026 New York State Alliance of MLSs, LLC. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

HighLights

Mixed‑use property with 1,976 SF first‑floor medical/office/retail space plus option to divide into two units
Second‑floor 1,344 SF 2‑bedroom apartment; upper unit is rented
Law firm lease on the lower commercial space and approx. $3,300/month total income reported
500 SF reinforced concrete vault with 16‑foot ceilings for secured storage or specialty use
Exterior updates include an 8‑year‑old tear‑off roof, vinyl siding, and newer windows
Rear paved parking area for up to six vehicles; security buzz‑in system and central air

Overview

This well maintained mixed-use building combines retail/professional space with an income-producing residential unit. The first floor includes approximately 1,976 square feet of medical, office, or retail space that can be divided into two separate units. The layout features a bright front retail or reception area, five private office or exam rooms, and two half bathrooms, with centralized amenities including central air, a wired sound system, and a security buzz-in system. Existing plumbing is carried to multiple rooms, supporting medical or professional configurations. A lower commercial space is currently leased to a law firm. The second floor provides an approximately 1,344 square foot two-bedroom apartment with a formal dining room and generous living area; the upper unit is rented.

The property is positioned along a busy Main Street corridor and includes exterior updates such as an eight-year-old tear-off roof, vinyl siding, and newer windows. A paved rear parking area accommodates up to six vehicles. In addition, there is a 500 square foot reinforced concrete vault with 16-foot ceilings for secured storage or specialty use.

For tenants, the first-floor configuration supports a range of medical or professional uses, with the option to split into two units. For investors or owner-operators, the building’s structure supports both commercial and residential income, with the lower space already leased to a law firm and the apartment currently rented.

Property Profile Location Intelligence

Current Use by Public Records

Blackley John C ... Physician Mathew E. Sendker, ... Physician Crinzi Alexander R ... Physician Leonard Patti L ... Physician Matthew E. Shepherd Physician

Suggested Use

Location Insight

Map
Local Demand

City: Buffalo
County: Erie
State: New York
Longitude: -78.847492
Latitude: 42.932077

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For sale
Mixed-use properties
NY
Buffalo
14214
2290 Main Street

What type of property is this?

Mixed-use property - Leased lower commercial space plus a two-bedroom apartment creates immediate rental income and flexible on-site professional use.

Where is this mixed-use property located?

The property is located at 2290 Main Street Buffalo, NY.

What is the asking price?

The asking price for this property is $399,000.

What are key features of this property?

This property features: Mixed‑use property with 1,976 SF first‑floor medical/office/retail space plus option to divide into two units; Second‑floor 1,344 SF 2‑bedroom apartment; upper unit is rented; Law firm lease on the lower commercial space and approx. $3,300/month total income reported

2290 Main Street, Buffalo, NY 14214

COMMERCIAL - Buffalo, NY

Property Features for 2290 Main Street

General Information

Taxes and HOA fees

Utilities

Building Details

We can help!

HighLights

Overview

Current Use by Public Records

Suggested Use

Location Insight

Nearby Similar for Sale

Flex Office/Warehouse with Drive-In Doors

Multi-Unit Office Building with Pylon Signage

Brick Live-Work Building with Apartment

Five-Unit Mixed-Use Building

Freestanding Auto Repair Shop

Turnkey Restaurant on Main Street

Versatile Commercial Building in Buffalo

Restaurant and Bar Building Opportunity

Two-Building Office Suite Property

Mixed-Use Restaurant and Warehouse

Harlem Road Commercial Opportunity

Harlem Road Commercial Opportunity

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