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Waltham Office and Lab Space
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225 Wyman St, Waltham, MA

500,000 SF development with flexible layouts and amenities.

Property Size26,190 SF
Lot Size14.21 Acres
Days on Market247

Property Features for 225 Wyman St

General Information

Standard status Active
Size 26,190 SF
Lot size 14.21 Acres
Property subtype LIFE_SCIENCE
Listing Agency: Cushman & Wakefield | Boston
Listed By: Ted Lyon · License #9569558
Source: Moodyscre
Added: Nov 25, 2025 Changed: Jul 6 Last Checked: Jul 30 at 2:28AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Cushman & Wakefield | Boston

Investment Insights

Based on property information with market context.

Located in the greater Boston innovation and life science community, 225 Wyman is a 500,000 SF development situated on over 6 acres with immediate access to Route 128 & I-95. Designed to optimize the workplace experience, the property features flexible, column-free floor plates ranging from 55,000 SF up to 136,000 SF. Custom workplace designs are available for labs and office configurations. The property includes a 3-acre landscaped courtyard with fully connected outdoor workspaces, a 10,000 SF boutique fitness center with locker rooms, and a 150-person flexible conference center space. On-site amenities include fast-casual dining with seating for 280+ people. An express shuttle service is available to Alewife Red Line MBTA Station & Commuter Rail Station. The property offers 26190 SQUARE_FEET of space.

Key Highlights

  • Immediate access to Route 128 & I‑95 in Boston's Innovation and life science community.
  • Flexible, column‑free floor plates ranging from 55,000 SF up to 136,000 SF.
  • Custom workplace designs available for labs & office configurations.

Property Analytics

Current Use

404 Wyman LLC Property Management Company Antonios Giakoumis - TIAA ... Financial Advisor Mark Bertonazzi - TIAA ... Financial Advisor Justin Catalano - TIAA ... Financial Advisor William Vigor - TIAA ... Financial Advisor

Suggested Use

Top Pick Auto Repair Shop Real Estate Agency Spa & Massage Center Big Box & Wholesale Store Hair Salon Auto Parts Store

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

735
Businesses Nearby

Market

Vacancy Rate% for Office in Northeast region

13.1% 2019
15.4% 2020
17.6% 2021
19.1% 2022
20.2% 2023
20.9% 2024
19.9% 2025
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Frequently Asked Questions

What type of property is this?
Office building - 500,000 SF development with flexible layouts and amenities.
Where is this office building located?
The property is located at 225 Wyman St Waltham, MA.
What are key features of this property?
This property features: Immediate access to Route 128 & I‑95 in Boston's Innovation and life science community.; Flexible, column‑free floor plates ranging from 55,000 SF up to 136,000 SF.; Custom workplace designs available for labs & office configurations.
(617) 279-4579 Call to check price and availability
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