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Greenville, NC Commercial Real Estate for Lease

62 results
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Office Space in Medical District
$1,500 /Mo
1,250 SF

Office Space in Medical District

835 Johns Hopkins Drive unit: C, Greenville, NC 27834

Office space for lease in Greenville's Medical District.

  • Office space available for lease in Greenville's Medical District.
  • Prime location in the Medical District of Greenville, NC.
  • Built in 2000.
  • Features electric heating.
  • Location coordinates: [-77.41369, 35.603806].
Updated: Feb 25
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Move-in Ready Greenville Office Spaces
$500 /Mo

Move-in Ready Greenville Office Spaces

404 St Andrews Drive unit: 15, Greenville, NC 27834

Individual office spaces available for lease with all-inclusive amenities.

  • Move‑in ready individual office spaces with flexible lease options. Choose a window or interior office to suit your needs and budget.
  • All‑inclusive amenities simplify budgeting and operations. Enjoy utilities, high‑speed internet, trash, and common area janitorial services.
  • Convenient central location provides easy access to major roadways, downtown, shopping, and dining.
  • Shared conference room and furnished break rooms offer professional meeting and relaxation spaces.
  • Ample on‑site parking ensures convenient access for tenants and clients.
Updated: Jul 31, 2025
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Move-in Ready Office Space Available
$2,800 /Mo
1,730 SF

Move-in Ready Office Space Available

Office space for lease with all-inclusive amenities in Greenville.

404 St Andrews Drive unit: 4, Greenville, NC 27834
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Move-in Ready Office Space Available
$2,850 /Mo
1,510 SF

Move-in Ready Office Space Available

Office space for lease in Greenville, NC with all-inclusive amenities.

404 St Andrews Drive unit: 3, Greenville, NC 27834
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Move-in Ready Office Space Available
$2,850 /Mo
1,575 SF

Move-in Ready Office Space Available

Well-maintained commercial property with flexible office options in Greenville, NC.

404 St Andrews Drive unit: 7, Greenville, NC 27834
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Move-in Ready Office Space Available
$2,900 /Mo
1,945 SF

Move-in Ready Office Space Available

Well-maintained office complex with flexible options and all-inclusive amenities.

404 St Andrews Drive unit: 5, Greenville, NC 27834
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Move-in Ready Office Space Available
$2,900 /Mo
1,775 SF

Move-in Ready Office Space Available

Well-maintained office complex with flexible leasing options and all-inclusive amenities.

404 St Andrews Drive unit: 10, Greenville, NC 27834
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Commercial Space For Rent
$1,875 /Mo
1,500 SF

Commercial Space For Rent

Commercial space available for rent in Greenville, North Carolina.

1909 E Fire Tower Road unit: C, Greenville, NC 27858
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Functional Office Space in Greenville
$1,500 /Mo
900 SF

Functional Office Space in Greenville

900 SF office suite with reception and private offices.

3105 S Evans St, Greenville, NC
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Retail Space in Established Area
$1,200 /Mo
750 SF

Retail Space in Established Area

Retail space available in established Greenville neighborhood.

100 E Victoria Ct, Greenville, NC
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Functional Warehouse Near Downtown Greenville
$8 SF/Yr
5,600 SF

Functional Warehouse Near Downtown Greenville

5,600 SF warehouse near downtown, ECU, and ECU Health.

204 W 10th St, Greenville, NC
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Retail Space Near East Carolina
$17 SF/Yr
3,261 SF

Retail Space Near East Carolina

Commercial space near East Carolina University and downtown Greenville.

211 S Jarvis St, Greenville, NC 27858
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Move-in Ready Office or Retail
Contact for pricing
1,200 SF

Move-in Ready Office or Retail

1,200 sqft space ideal for office, retail, or medical use.

803 Moye Boulevard, Greenville, NC 27834
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Medical Office in Greenville's District
$16 SF/Yr
5,795 SF

Medical Office in Greenville's District

Freestanding medical/office building in Greenville's medical district for lease.

855 Johns Hopkins Dr, Greenville, NC
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Medical Office Suite For Rent
$18 SF/Yr
1,755 SF

Medical Office Suite For Rent

1,755 SF medical office suite in a desirable location.

1011 WH Smith Blvd, Greenville, NC
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Professional Office Space in Greenville
$13 SF/Yr
1,705 SF

Professional Office Space in Greenville

Conveniently located office space near ECU and ECU Health.

612 Country Club Dr, Greenville, NC
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Retail Space in Lynndale Shoppes
$20 SF/Yr
1,216 SF

Retail Space in Lynndale Shoppes

3,050 SF retail space in a busy commercial corridor.

505 Red Banks Rd, Greenville, NC
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Commercial Pad Site For Lease
Contact for pricing

Commercial Pad Site For Lease

0.80-acre pad site available for ground lease.

3501 Galleria Drive, Greenville, NC 27834
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Retail Space Near ECU Health
$1,500 /Mo
800 SF

Retail Space Near ECU Health

800 sqft retail space with high visibility available for lease.

1301 W 14th Ave, Greenville, NC
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New Flex Industrial Project
$10 SF/Yr
10,800 SF

New Flex Industrial Project

Developing flex industrial park with versatile spaces for rent.

1105 Greenville Blvd SW, Greenville, NC
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Greenville Medical Office Space Available
Contact for pricing
7,979 SF

Greenville Medical Office Space Available

Premier medical office space for sale or lease in Greenville.

2459 Emerald Pl, Greenville, NC
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High-Visibility Retail Corner Site
Contact for pricing

High-Visibility Retail Corner Site

Freestanding building or ground lease opportunity in Greenville, NC.

110 Greenville Boulevard Southeast, Greenville, NC 27858
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Office and Flex Space Available
$16 SF/Yr
4,325 SF

Office and Flex Space Available

Office and warehouse/flex space near Greenville for lease.

4597 US-264, Greenville, NC 27834
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Downtown Retail or Office Space
$12 SF/Yr
4,476 SF

Downtown Retail or Office Space

Prime downtown Greenville retail or office space for rent.

416 Evans St, Greenville, NC
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Greenville, NC Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Greenville, NC with 62 listings featured on our commercial real estate exchange. The current inventory includes 4,363,884,360 square feet of properties with an estimated lease value of $349 /Mo.

Estimated lease rates for Commercial real estate in Greenville, NC begin at $4 SF/Yr, with an average of $17 SF/Yr and extend to $40 SF/Yr.
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