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Independence, MO Commercial Real Estate for Sale

172 results
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Downtown Independence Commercial Building For Sale
$1,300,000
0.30 Acres

Downtown Independence Commercial Building For Sale

120 S Liberty St, Independence, MO 64050

Well-maintained commercial building in Downtown Independence, suitable for various uses.

  • Prime location in the heart of Downtown Independence with excellent visibility and accessibility.
  • Well‑maintained commercial building suitable for a variety of uses.
  • Newer roof (2 years old).
  • Relatively new HVAC system (5 years old).
  • Parking Lot included.
Updated: Dec 17, 2025
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Remodeled Commercial Space on High-Traffic
$250,000
0.20 Acres

Remodeled Commercial Space on High-Traffic

307 E 23Rd St, Independence, MO 64055

Affordable, remodeled commercial space with high visibility and business potential.

  • High‑traffic location on 23rd Street with HUGE business potential.
  • Fully remodeled interior and exterior.
  • Standalone commercial space with C‑2 zoning.
  • 18' tall pole sign with HIGH visibility.
  • Multiple office spaces: 2 large, 1 open.
Updated: Dec 26, 2025
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Turnkey Restaurant and Real Estate
$3,380,000
1.27 Acres

Turnkey Restaurant and Real Estate

Fully operational restaurant with real estate, high visibility, easy access.

19800 E Valley View Pkwy, Independence, MO 64057
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Independence Commercial Property with Mechanic's Shop
$475,000
0.37 Acres

Independence Commercial Property with Mechanic's Shop

Commercial property featuring a mechanic's shop, office, and service garage.

10058 E Wilson Rd, Independence, MO 64053
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Updated Retail Space, Independence, MO
$775,000
0.77 Acres

Updated Retail Space, Independence, MO

Updated retail space with accessibility to I-70 and US-40.

4541 S Noland Rd, Independence, MO 64055
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Historic Independence Square Retail Building
$850,000
0.23 Acres

Historic Independence Square Retail Building

Commercial building in historic Independence Square with investment potential.

111 N Main St, Independence, MO 64050
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Two-Level Retail Store For Sale
$400,000
0.48 Acres

Two-Level Retail Store For Sale

Free-standing two-level retail store with billboard income included.

2854 S 291 Hwy, Independence, MO 64057
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Reformed Office Space in Independence
$119,000
0.13 Acres

Reformed Office Space in Independence

Charming office space in a reformed residential home.

911 E 23Rd St, Independence, MO 64055
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Retail Center in Independence, MO
$1,300,000
1.17 Acres

Retail Center in Independence, MO

Fully leased retail neighborhood center in Independence, Missouri.

2400 Lee's Smt Rd, Independence, MO 64055
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Income Producing Retail Property
$295,000
0.41 Acres

Income Producing Retail Property

Fully occupied retail property with separate utilities in Independence, MO.

11717-11723 E 23Rd St, Independence, MO 64050
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Commercial Building with Multiple Units
$475,000
0.43 Acres

Commercial Building with Multiple Units

Commercial building with nine units, potential for $5,000+ monthly income.

3501 S Sterling Ave, Independence, MO 64052
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Independence, MO Commercial Building
Pending
$1,000,000
0.43 Acres

Independence, MO Commercial Building

Commercial building with laundromat and mini mart for sale.

10215 E Truman Rd, Independence, MO 64052
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Independence Commercial Building For Sale
$365,000
0.28 Acres

Independence Commercial Building For Sale

3,456 SF commercial building on high-traffic corner lot.

13717 E 39Th St, Independence, MO 64055
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Triplex with Rental Income Potential
$265,000

Triplex with Rental Income Potential

Three independent units offering immediate rental income and investment potential.

101 S Willis Ave, Independence, MO 64050
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Prime Office Building, Independence, MO
$449,000
0.17 Acres

Prime Office Building, Independence, MO

High-visibility office, ample parking, owner financing possible.

129 23Rd St, Independence, MO 64055
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Prime Independence Office Space
$149,900
0.13 Acres

Prime Independence Office Space

Charming Office, Ideal Location, $149,900

911 23Rd St, Independence, MO 64055
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Prime Independence Office Building
$399,000
0.96 Acres

Prime Independence Office Building

Updated Office Space, Huge Potential

301 M 291 Hwy, Independence, MO 64056
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Prime Independence Office Building
$850,000
2.94 Acres

Prime Independence Office Building

Spacious Office Building on 3 Acres

11610 Truman Rd, Independence, MO 64050
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Independence Retail Space - $950k
$950,000

Independence Retail Space - $950k

High-traffic retail space, I-70 & US-40 access.

4541 Noland Rd, Independence, MO 64055
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Independence Office Building & Vet Clinic
$500,000

Independence Office Building & Vet Clinic

Established Vet Practice, Great Opportunity

13717 39Th St, Independence, MO 64055
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Updated Condo in Heritage Park
$150,000

Updated Condo in Heritage Park

Updated 2-bedroom, 2-bath condo with community amenities.

4007 S Crysler Ave, Independence, MO 64055
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Truman Road Warehouse - $850K
$850,000
2.94 Acres

Truman Road Warehouse - $850K

Prime Independence Warehouse, 2-Story, 2.94 Acres

11610 Truman Rd, Independence, MO 64050
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Independence Warehouse - Huge Shop!
$150,000

Independence Warehouse - Huge Shop!

Industrial warehouse, 2160 sq ft, great potential.

220 Glenwood Ave, Independence, MO 64053
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Prime Independence Commercial Space
$850,000

Prime Independence Commercial Space

Versatile 20,000 sq ft building, great location.

4621 Shrank Dr, Independence, MO 64055
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Independence, MO Commercial Real Estate Investment Opportunities Market Analysis

Explore 2197 commercial real estate investment opportunities in Independence, MO with 172 listings featured on our commercial real estate marketplace. The current inventory includes 171,485,621 square feet of properties with an estimated value of $519,442,417.

Estimated prices for commercial real estate in Independence, MO begin at $35,000, with an average of $370,236 and extend to $6,198,326.

In Independence, MO, current investment values show:

  • Retail properties positioned at $360,454
  • Individual retail properties measuring $387,080
  • Retail space assessed at $402,708
  • Automotive properties calculated at $282,589
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