353 University AVE, Palo Alto, CA 94301

Building Details

Year built

1972

Roof type

Tar/Gravel

Listing agent Rajendra Naidoo License #01160416 Show Phone

Listing office Tavena Realty Group r**@tavena.com 6197 Gerdts Drive, Woodside, CA Show Phone

Listing date Mar 29, 2026

Report an issue

MLS# ML82019216

Copyright © 2026 MLS Listings, Inc. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

---

Overview

Located at 353 University Ave in downtown Palo Alto, this multi-use commercial suite totals over 6,014 sq. ft. It includes five offices, a large main area, and two restrooms, providing a practical layout for tenant organizations that need both private workspace and an open operating floor. The property is zoned Commercial.

The suite is positioned on University Avenue near Florence, surrounded by a mix of well-known retailers and dining options. Nearby businesses listed include an Apple Store, Brandy Melville, Salt & Straw, CVS Pharmacy, Crepevine, The RealReal, Rooh, IL Fornaio, and Chico’s Pizza My Heart, along with other local retail.

The configuration supports a variety of professional and public-facing uses, including high-tech offices, retail, restaurant concepts, and financial services, as indicated by the current marketing materials. With multiple offices plus a sizeable main area, it can accommodate teams that require separate rooms while maintaining a dedicated customer or client-facing space. The downtown setting is also close to Stanford University, medical uses, and Palo Alto City Hall.

Suggested Use

Real Estate Agency Restaurant Law Firm Spa & Massage Center Dental Office Hair Salon Nail Salon Building Supply Auto Repair Shop Gym & Fitness Center

Zoning and permitted uses should be independently verified with local authorities.

Location Insight

• Map
• Local Demand

City

Palo Alto

County

Santa Clara

State

California

Longitude

-122.1611135

Latitude

37.446719

Nearby Similar for Lease

• Sponsored

  

  Contact for pricing

  CA, Palo Alto - Page Mill Rd

  425 Page Mill Rd, Palo Alto, CA 94306

  View Details
• 

  $129-$62,635/Mo

  11-2,145 SF

  4 Palo Alto Square

  3000 El Camino Real, Unit 4, Palo Alto, CA 94306

  View Details
• 

  $129-$51,680/Mo

  11-2,017 SF

  Embarcadero Place

  2100 Geng Rd, Unit 210, Palo Alto, CA 94303

  View Details
• 

  $129-$21,036/Mo

  11-1,292 SF

  Hamilton Avenue

  228 Hamilton Ave, Unit 3RD, Palo Alto, CA 94301

  View Details
• 

  $7,380/Mo

  1,200 SF

  Prime Midtown Palo Alto Retail

  Retail/service space in Palo Alto's Midtown neighborhood.

  706 Colorado Ave, Palo Alto, CA 94303

  View Details
• 

  $129-$62,478/Mo

  11-2,078 SF

  CA, Palo Alto - 200 Page Mill Road

  200 Page Ml Rd Ste 200, Unit 2ND, Palo Alto, CA 94306

  View Details
• 

  $6 SF/Yr

  5,387 SF

  Plug-and-Play Office Suite

  Move-in ready office with 27 workstations, three conference rooms, and a kitchenette for collaborative teams.

  385 Forest Ave, Palo Alto, CA 94301

  View Details
• 

  $2 SF/Yr

  14,318 SF

  Palo Alto Flex Space

  Versatile 14,318 SF space ideal for various businesses.

  3780 Fabian Way, Palo Alto, CA, 94303

  View Details
• 

  $87 SF/Yr

  7,400 SF

  Downtown Palo Alto Freestanding Office

  Freestanding office building in prime downtown location for sublease.

  411 High Street, Palo Alto, CA 94301

  View Details
• 

  $43,601 SF/Yr

  6,014 SF

  Downtown Mixed-Use Retail Office Space

  Versatile downtown suite with multiple offices, large open area, and two restrooms for office, retail, or restaurant users.

  353 University Avenue, PALO ALTO, CA 94301

  View Details
• 

  $6 SF/Yr

  4,174 SF

  Palo Alto Office Sublease Available

  Sublease office space with workstations and parking near Caltrain.

  101 University Avenue, Palo Alto, CA, 94301

  View Details
• 

  $6 SF/Yr

  2,100 SF

  Freestanding Office/Tech/Medical Space Available

  2,100 SF office/tech/medical space with parking near El Camino.

  450 Sheridan Ave, Palo Alto, CA 94306

  View Details

FAQs

What type of property is this?

Office units - Flexible suite with two restrooms, five offices, and a large main area for office, retail, or restaurant concepts.

Where is this office units located?

The property is located at 353 University AVE Palo Alto, CA.

What is the lease rate?

The lease rate is $43,601.

What are key features of this property?

This property features: Prime downtown Palo Alto location on University Avenue and Florence.; High foot traffic area.; Versatile 6,014 sq. ft. unit suitable for various businesses.