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Appleton, WI Commercial Real Estate for Sale

142 results
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Prime Commercial Land in Appleton
$399,000
5.25 Acres

Prime Commercial Land in Appleton

W6471 Manitowoc Rd, Appleton, WI 54915

5.25 acre commercial land parcel with high visibility.

  • Prime intersection location on Manitowoc Road & Lake Park Road offering unparalleled visibility and accessibility.
  • Approximately 5.25 acre parcel provides a large canvas for development.
  • Suitable for diverse range of commercial businesses.
  • Existing light commercial utility building adds versatility.
  • Public water and sewer connections available.
Updated: Dec 16, 2025
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Appleton Office Building For Sale
$8,990,000
115,776 SF

Appleton Office Building For Sale

1101 South River St, Appleton, WI 54915

Premier office property in Appleton, WI, with high visibility.

  • Premier office property located along the scenic South River.
  • Well‑maintained commercial building.
  • Rare combination of functionality, visibility, and location.
  • Ideal for a wide range of professional uses.
  • Stone construction.
Updated: Oct 21, 2025
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Appleton Office Space For Lease
Contact for pricing
115,776 SF

Appleton Office Space For Lease

Office space for lease near Lawrence University in Appleton, WI.

1111 South River St, Appleton, WI 54915
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Move-in Ready Appleton Office Space
Contact for pricing
115,776 SF

Move-in Ready Appleton Office Space

Three-story office building with parking near Lawrence University.

1111 South River St, Appleton, WI 54915
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Fox Valley Supper Club Opportunity
$374,900
5,600 SF

Fox Valley Supper Club Opportunity

Iconic supper club with living space on 2.75 acres.

4899 County Road Ee, Appleton, WI 54911
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Versatile Commercial Building on High-Traffic Street
$899,900
11,392 SF

Versatile Commercial Building on High-Traffic Street

11,000+ sq ft commercial building with high visibility.

2415 N Richmond St, Appleton, WI 54911
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Downtown Commercial Building with Parking
$299,900

Downtown Commercial Building with Parking

Downtown Appleton commercial building suitable for office or retail use.

222 S State St, Appleton, WI 54911
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Commercial Corner Near Fox River
$399,000

Commercial Corner Near Fox River

Commercial land with high visibility and access near Fox River.

1734 N Olde Casaloma Dr, Appleton, WI 54913
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Commercial Land Near Airport
$500,000

Commercial Land Near Airport

Land ideal for development in high-traffic commercial district.

4800-4820 W Packard St, Appleton, WI 54913
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Established Kennel and Grooming Business
$849,900
6,500 SF

Established Kennel and Grooming Business

Turnkey dog kennel and grooming business with real estate included.

Confidential Listing, Appleton, WI
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Appleton Retail Center For Sale
$2,500,000
21,500 SF

Appleton Retail Center For Sale

Retail center with high visibility and ample parking.

4040-4090 W Spencer St, Appleton, WI 54914
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East Appleton Retail Outlots
$632,000
1 SF

East Appleton Retail Outlots

Prime retail outlots available in East Appleton.

Van Roy Rd, Appleton, WI 59415
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Commercial Land For Sale
$675,000

Commercial Land For Sale

1.3036 acre commercial land with development potential.

2000 E Edgewood Dr, Appleton, WI 54913
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Class A Office Building Opportunity
$16,000,000
59,010 SF

Class A Office Building Opportunity

Premier office building in prime Fox Valley location for sale.

425 Better Way, Appleton, WI 54911
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Appleton Restaurant Business For Sale
$299,000

Appleton Restaurant Business For Sale

Restaurant business for sale with FF&E and naming rights.

Business For Sale, Appleton, WI
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Commercial Land Near Fox River
$90,000

Commercial Land Near Fox River

Commercial land with high visibility near the Fox River Mall.

33 Park Pl, Grand Chute, WI 54914
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Appleton Warehouse with Showroom Frontage
$1,400,000
27,850 SF

Appleton Warehouse with Showroom Frontage

Functional industrial/warehouse building with showroom, ideal for owner-occupiers.

311 N Superior St, Appleton, WI 54911
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Appleton Warehouse with Loading Dock
$1,200,000
12,800 SF

Appleton Warehouse with Loading Dock

12,800 SF warehouse featuring loading dock and billboard income.

234 W Northland Ave, Appleton, WI 54911
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Commercial Land in Tri-Park Business
$343,000

Commercial Land in Tri-Park Business

Land in a professional business park with utilities available.

Tri-Park Way & Innovation Ct, Appleton, WI
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Commercial Land Near Appleton Airport
$75,000

Commercial Land Near Appleton Airport

Commercial land available near downtown Appleton and the airport.

Spencer St, Appleton, WI 54914
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Vacant Land Near I-41
$245,000

Vacant Land Near I-41

Vacant commercial land with easy highway access, ready for development.

W Prospect Ave, Appleton, WI 54911
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Renovated Office Building Near I-41
Contact for pricing
5,776 SF

Renovated Office Building Near I-41

Recently renovated office building with large parking lot near I-41.

302 S Bluemound Dr, Appleton, WI 54914
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Prime Land on N Perkins
$299,000

Prime Land on N Perkins

1.9 acres with frontage on N Perkins Street.

W College Service Rd, Appleton, WI
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Retail Space Near Walmart
Contact for pricing
23,622 SF

Retail Space Near Walmart

Retail property with high visibility and strong market advantages.

3525 E Calumet St, Appleton, WI 54915
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Appleton, WI Commercial Real Estate Investment Opportunities Market Analysis

Explore 110 commercial real estate for sale in Appleton, WI, showcased through 142 active listings on our real estate platform. These investment opportunities span a total of 7,228,033 square feet of properties for sale, with an estimated market value of $40,770,520.

Sale prices for business properties in Appleton, WI start at $91,200, averaging $1,630,820, and reaching up to $8,990,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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