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Weslaco, TX Commercial Real Estate for Sale

295 results
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Medical Building Near Knapp Medical
$727,000
5,243 SF

Medical Building Near Knapp Medical

1412 E 8Th St, Weslaco, TX 78596

Medical building next to Knapp Medical Center with income potential.

  • Prime location next to Knapp Medical Center and surrounded by various medical facilities.
  • Building is divided with two separate electric meters, offering potential for leasing one or both sides.
  • Total building size of 5,243 sq. ft. with two suites: 3,383 sq. ft. and 1,860 sq. ft.
  • Ample parking with 22 spaces plus a covered area for 10 cars.
  • Features two large lobby areas, business/receptionist offices, and exam rooms.
Updated: Sep 4, 2025
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Weslaco Mixed-Use Fixer-Upper Opportunity
Pending
$150,000
1,276 SF

Weslaco Mixed-Use Fixer-Upper Opportunity

149 N Texas Blvd, Weslaco, TX 78596

Commercial/residential space in Weslaco, TX, needing full remodel.

  • Prime location just off Texas Blvd in Weslaco with high visibility and easy access.
  • Zoned for both commercial and residential use, offering flexible usage options.
  • Full kitchen and 3‑room layout provides a solid foundation for customization.
  • Opportunity to fully customize the space through a complete remodel.
  • Central heating and cooling already in place.
Updated: Oct 23, 2025
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Turnkey Restaurant & Entertainment Space
$900,000
3,100 SF

Turnkey Restaurant & Entertainment Space

High-visibility restaurant with outdoor entertainment area near US-Mexico border.

1015 S International Blvd, Weslaco, TX 78596
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Restaurant Building in High Traffic Area
$750,000
7,738 SF

Restaurant Building in High Traffic Area

Large restaurant with indoor and outdoor dining in Weslaco, TX.

2708 N Texas Blvd, Weslaco, TX 78599
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Mixed-Use Property in Weslaco, TX
$350,000
4,704 SF

Mixed-Use Property in Weslaco, TX

Mixed-use property with three detached buildings in a prime location.

319 E Los Torritos St, Weslaco, TX 78596
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Versatile Commercial Property in Weslaco
$175,000
4,000 SF

Versatile Commercial Property in Weslaco

Multi-use property in Weslaco, suitable for offices, retail, or church.

320 E Huisache St, Weslaco, TX 78596
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Weslaco Plaza for Medical Purposes
$2,395,000
19,200 SF

Weslaco Plaza for Medical Purposes

19,200 SF plaza on 1.75 acres in Weslaco, TX.

1125 James St, Weslaco, TX 78596
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Weslaco Industrial Lot - Prime Location
$760,403
203,222 SF

Weslaco Industrial Lot - Prime Location

High-Demand Industrial Land, Excellent Access

000 Development Dr Dr, Weslaco, TX 78596
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Weslaco Medical Plaza Investment
$2,495,000
19,200 SF

Weslaco Medical Plaza Investment

High-yield medical plaza, prime location.

1125 James St, Weslaco, TX 78596
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Weslaco Commercial Property w/ Mobile Home
$295,000
2,272 SF

Weslaco Commercial Property w/ Mobile Home

Versatile Commercial Space & Rental Income

2609 Granada, Weslaco, TX 78599
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Weslaco Commercial Building - Prime Location
$165,000
1,705 SF

Weslaco Commercial Building - Prime Location

Versatile 1705 SF building, excellent accessibility.

2505 Bridge Ave, Weslaco, TX 78599
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1504 Pike Blvd, Weslaco, TX 78596
$1,200,000
6,768 SF

1504 Pike Blvd, Weslaco, TX 78596

Commercial real estate • 6,768 SF

1504 Pike Blvd, Weslaco, TX 78596
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Weslaco Commercial Space - High Visibility
$449,000
3,410 SF

Weslaco Commercial Space - High Visibility

Prime Weslaco location, high traffic, leased to tenant.

505 Angelita Dr, Weslaco, TX 78599
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Weslaco Strip Center Investment Opportunity
$2,500,000
8,100 SF

Weslaco Strip Center Investment Opportunity

High-Yielding, Fully Leased Commercial Property

1321 Ricardo St, Weslaco, TX 78599
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Weslaco Commercial Building - Hwy 2
$1,500,000
5,559 SF

Weslaco Commercial Building - Hwy 2

High-traffic location, versatile space, great investment.

1420 Interstate 2 Hwy, Weslaco, TX 78596
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Weslaco Retail Center - High ROI
$1,081,005
8,985 SF

Weslaco Retail Center - High ROI

Prime Retail Space, High Traffic Area, Excellent CAP Rate

900 International Blvd, Weslaco, TX 78599
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Weslaco Commercial Corner Lot Investment
$1,287,000
2,826 SF

Weslaco Commercial Corner Lot Investment

High-traffic corner lot, ideal for retail or restaurant

1110 Expressway 83, Weslaco, TX 78599
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Weslaco Warehouse: Prime Location
$225,000
4,400 SF

Weslaco Warehouse: Prime Location

Spacious warehouse, ideal for diverse uses.

1715 Abilene Dr, Weslaco, TX 78599
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Weslaco Commercial Plaza - High Growth Area
$475,000
1,800 SF

Weslaco Commercial Plaza - High Growth Area

Five-unit potential, high-traffic location.

4498 International Blvd, Weslaco, TX 78599
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Weslaco Expressway 83 Business Park
$980,000
4,560 SF

Weslaco Expressway 83 Business Park

High-Visibility Commercial Property, Excellent Potential

4038 Expressway 83, Weslaco, TX 78596
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00 Economic Ave Ave, Weslaco, TX 78596
$750,633
200,744 SF

00 Economic Ave Ave, Weslaco, TX 78596

Industrial properties • 200,744 SF

00 Economic Ave Ave, Weslaco, TX 78596
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Weslaco Retail Property - $350K
$350,000
3,280 SF

Weslaco Retail Property - $350K

Grocery Store, 3280 sq ft, 12 parking spaces

2609 Mid Vly Dr, Weslaco, TX 78599
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Weslaco Fourplex: Prime Investment
$445,000

Weslaco Fourplex: Prime Investment

New Construction, 4 Units, High ROI Potential

2808 Delta Rd, Weslaco, TX 78596
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Weslaco Multifamily Investment Opportunity
$285,000
2,279 SF

Weslaco Multifamily Investment Opportunity

Fourplex, 4 Units, High Rental Income Potential

1309 Gonzalez Rd, Weslaco, TX 78596
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Weslaco, TX Commercial Real Estate Investment Opportunities Market Analysis

Explore 1739 commercial real estate investment opportunities in Weslaco, TX with 295 listings featured on our commercial real estate marketplace. The current inventory includes 100,650,381 square feet of properties with an estimated value of $511,111,210.

Estimated prices for commercial real estate in Weslaco, TX begin at $32,000, with an average of $402,766 and extend to $8,000,000.

In Weslaco, TX, current investment values show:

  • Retail properties positioned at $344,055
  • Office Properties & Spaces measuring $378,219
  • Office buildings assessed at $353,902
  • Other commercial real estate calculated at $577,427
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