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Madison County, TX Commercial Real Estate for Sale

78 results
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Madisonville Commercial Hospitality/Retail Suites
$950,000
12,630 SF

Madisonville Commercial Hospitality/Retail Suites

710 S May St, Madisonville, TX 77864

Newly renovated hospitality/retail suites in the heart of Madisonville, TX.

  • High‑visibility location on S. Hwy 75 with frontage and a second entrance on South St.
  • Newly renovated and built‑out suites offering flexible food service, vending, and storefront spaces.
  • Currently operating as a successful Pizza Eatery, Biergarten, Retail Clothing and Food Vendor Park.
  • Located in the heart of Madisonville, TX, offering small‑town charm with modern conveniences.
  • Minutes from I‑45 access, centrally located between Palestine and Bryan College Station in the Houston‑Dallas Corridor.
Updated: Mar 5
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Medical Facility on Main Street
Contact for pricing
2,940 SF

Medical Facility on Main Street

2006 E Main St, Madisonville, TX 77864

Near-new medical facility in growing rural community.

  • Constructed in 2021: Near‑new medical facility minimizing immediate maintenance concerns.
  • Prime Location: Prominently placed on Main St., less than 1 minute from I‑45, overlooking Madisonville, TX.
  • Turnkey Spaces: Offers a wide range of suite sizes and turnkey spaces ready for immediate occupancy.
  • Ample Parking: Structured parking available for both employees and patients.
  • Functional Layout: Features a spacious lobby, patient check‑in, training area, nurses' station, doctor's office, breakroom, storage, 6 exam rooms, and 4 half bathrooms.
Updated: Dec 24, 2025
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Game Room and Cafe
$175,000
0.16 Acres

Game Room and Cafe

Game room and cafe with slot machines and hamburgers.

12108 State Highway 21 East, Midway, TX 75852
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Madisonville Land with Spacious Home
$939,800
2,975 SF

Madisonville Land with Spacious Home

30-acre property featuring a 2,975 sq ft home.

2117 Fm 2289, Madisonville, TX 77864
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Commercial Land in Downtown Madisonville
$50,000
0.12 Acres

Commercial Land in Downtown Madisonville

Prime commercial land in downtown Madisonville, Texas.

806 S Madison St, Madisonville, TX 77864
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Prime Commercial Land in Madisonville
$595,000
1.51 Acres

Prime Commercial Land in Madisonville

Exceptional development opportunity in high-traffic Madisonville, Texas.

1623 E Main St, Madisonville, TX 77864
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Income-Producing Estate with Event Venue
$2,250,000
8,365 SF

Income-Producing Estate with Event Venue

30-acre estate with renovated home and event center.

601 N Shipp St, Madisonville, TX 77864
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Income-Producing Madisonville Estate
$2,250,000
30.05 Acres

Income-Producing Madisonville Estate

30-acre estate with home, venue, and amenities near downtown.

601 N Shipp St, Madisonville, TX 77864
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Versatile Commercial Property in Madisonville
$289,000
750 SF

Versatile Commercial Property in Madisonville

Mixed-use property with apartment, storage, and development potential.

212 S Tammye Ln, Madisonville, TX 77864
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10 Acres in North Zulch
$155,000
10.00 Acres

10 Acres in North Zulch

10 acres of open Texas countryside with agricultural exemption.

11066 Jinkins Rd, North Zulch, TX 77872
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Land in North Madison County
$199,000
7.98 Acres

Land in North Madison County

8-acre property with potential for residence, ranchette, or investment.

9486 Puddin Ln, Madisonville, TX 77864
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Unrestricted Land Near Madisonville, TX
$534,900
44.78 Acres

Unrestricted Land Near Madisonville, TX

44.78 acres of unrestricted land, ideal for agricultural or recreational use.

11271 Jinkins Rd, North Zulch, TX 77872
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Agricultural Land in Madisonville, TX
$450,000
18.00 Acres

Agricultural Land in Madisonville, TX

18-acre agricultural tract suitable for livestock and hay production.

4853 Fm 1428, Madisonville, TX 77864
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Midway, Texas Land Tract
$299,000
19.84 Acres

Midway, Texas Land Tract

19-acre tract in Midway, TX with utilities and road frontage.

109 Old Sign Rd County Rd, Midway, TX 75852
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Midway Land for Sale
$199,950
11.50 Acres

Midway Land for Sale

11.5 acres of open land suitable for building or recreation.

Bozeman Ferry Rd, Midway, TX 75852
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Heavily Wooded Land in Midway, TX
$120,000
10.00 Acres

Heavily Wooded Land in Midway, TX

10 acre wooded land with road frontage near Houston, Dallas.

FM-2158 Farm To Market Rd, Midway, TX 75852
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Scenic Land with Trinity River Frontage
$487,604
37.51 Acres

Scenic Land with Trinity River Frontage

Unrestricted 37.5-acre property with diverse potential in Midway, Texas.

37.5 Antioch Rd, Midway, TX 75852
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Unrestricted Acreage in Madisonville, TX
$275,000
14.04 Acres

Unrestricted Acreage in Madisonville, TX

Unrestricted acreage ideal for homesite, recreation, equestrian, or agriculture.

14 Ac Halliday Ln, Madisonville, TX 77864
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Downtown Madisonville Commercial Building
$125,000
1,776 SF

Downtown Madisonville Commercial Building

Established commercial building in downtown Madisonville, Texas.

205 N Madison St, Madisonville, TX 77864
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Prime Pad Site in Madisonville
$544,500

Prime Pad Site in Madisonville

1-acre pad site with highway frontage near I-45.

E Main St, Madisonville, TX 77864
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Prime Commercial Land Opportunity
$660,000

Prime Commercial Land Opportunity

Commercial land for sale in Madisonville, Texas.

700 N May St, Madisonville, TX 77864
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Madisonville Commercial Land on Highway
$355,000

Madisonville Commercial Land on Highway

1.81 acre commercial land with highway frontage in Madisonville, TX.

200 E Park St, Madisonville, TX 77864
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Madisonville Ranch Home on Acres
$875,000

Madisonville Ranch Home on Acres

Ranch home on 29.66 acres with multiple structures.

4988 Paso Fino Ln, Madisonville, TX 77864
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Serene Country Home on Acres
$780,000

Serene Country Home on Acres

Home on 14.32 acres with detached three-car garage.

2604 Kashka Ln, Madisonville, TX 77864
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Madison County, TX Commercial Real Estate Investment Opportunities Market Analysis

Explore 61 commercial real estate for sale in Madison County, TX, showcased through 78 active listings on our real estate platform. These investment opportunities span a total of 12,220,915 square feet of properties for sale, with an estimated market value of $13,194,254.

Sale prices for business properties in Madison County, TX start at $50,000, averaging $599,738, and reaching up to $2,590,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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