Deaf Smith County, TX Commercial Real Estate for Sale

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Downtown Retail and Office Building
Updated: Jul 16
Downtown Retail and Office Building

601 Main Street, Hereford, TX 79045

$600,000
5,800 sqft 0.50 AC lot
Excellent downtown location with "C‑1" Commercial Retail zoning.
Potential to be reconfigured into separate spaces for up to 3 businesses.
Ample parking with street‑side spaces and an asphalt parking lot.
Features 9 offices, a great room, and a chapel.
Includes 5 HVAC units.
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Hereford Commercial Office/Warehouse for Trucks
Updated: Dec 31, 2025
Hereford Commercial Office/Warehouse for Trucks

109 Pine Street, Hereford, TX 79084

$700,000
10,320 sqft 2.99 AC lot
Four large bays designed for semi‑truck maintenance and repair.
Includes specialized bays for washing, oil changing, cleaning, and general truck work.
Large office space suitable for managing operations.
Substantial 2.9‑acre lot provides ample space for truck maneuvering and storage.
Entire property is fenced, enhancing security.
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Retail Storefront on Main Street
Retail Storefront on Main Street

208 N Main Street, Hereford, TX 79045

$140,500
2,553 sqft

Retail storefront for sale at 208 N Main Street in Hereford, Texas.

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Live-Work Building with Two Floors
Live-Work Building with Two Floors

208 & 212 N. Main Street, Hereford, TX 79045

$399,900
6,553 sqft

Residential space is positioned on the second floor above a versatile commercial unit on Main Street.

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Commercial Opportunity in Hereford, Texas
Commercial Opportunity in Hereford, Texas

621 E 1st Street, Hereford, TX 79045

$399,000
4,461 sqft 0.29 AC lot

Commercial property on HWY 60, great for business growth.

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Warehouse with Overhead Doors
Warehouse with Overhead Doors

120 Witherspoon Avenue, Hereford, TX 79045

$339,900
7,388 sqft 0.69 AC lot

Fenced warehouse with four overhead doors, offices, a restroom, and parking in a gated lot in Hereford, TX.

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Hereford Commercial Property For Sale
Hereford Commercial Property For Sale

706 E 5th Street, Hereford, TX 79045

$269,000
2,350 sqft 0.16 AC lot

Commercial property in Hereford, TX, suitable for bakery or cafe.

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Live-Work Commercial Property
Live-Work Commercial Property

212 N. Main Street, Hereford, TX 79045

$220,000
4,000 sqft

Property includes a commercial space plus a 2-bedroom, 2-bath living area for on-site use or investment.

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Hereford, TX Commercial Property
Hereford, TX Commercial Property

344 E 3rd Street, Hereford, TX 79045

$399,000
4,884 sqft 0.11 AC lot

Versatile commercial property with high ceilings and rustic charm.

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Live-Work Property with Two-Bed Home
Live-Work Property with Two-Bed Home

212 N Main Street, Hereford, TX 79045

$220,000
4,000 sqft 1.15 AC lot

Combination commercial space and 2-bedroom, 2-bath residence on 1.15 acres in Hereford.

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Automotive Flex Building
Automotive Flex Building

120 Witherspoon Avenue, Hereford, TX 79045

$350,000
7,388 sqft 0.69 AC lot

Fenced commercial flex building with multiple overhead doors, offices, and a parts-room garage suited for service or storage use.

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Metal Shop Building with Overhead Doors
Metal Shop Building with Overhead Doors

3994 County Road 7, Hereford, TX 79045

$220,000
1.22 AC lot

Versatile metal shop on a fenced 1.22-acre lot with multiple overhead doors, office space, and overhead crane.

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Hereford Commercial Property For Sale
Hereford Commercial Property For Sale

316 N 25 Mile Avenue, Hereford, TX 79045

$345,000
0.57 AC lot

Corner lot with business potential on high-traffic street.

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Hereford TX Commercial Property
Hereford TX Commercial Property

344 E 3rd St, Hereford, TX 79045

$399,000
4,884 sqft

Commercial property for sale in Hereford, Texas.

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Perimeter-Fenced Shop and Office
Perimeter-Fenced Shop and Office

3880 U.S. Hwy 385, Hereford, TX 79045

$600,000

A fenced shop building with office/work area sits on a highway-front tract outside Hereford city limits.

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Office Building with Multiple Offices
Office Building with Multiple Offices

321 W 3rd Street, Hereford, TX 79045

$475,000

Building offers multiple office rooms plus front and rear parking, with a beauty shop on the west end.

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Retail Storefront Property
Retail Storefront Property

208 N. Main Street, Hereford, TX 79045

$140,500
2,553 sqft

Retail storefront offered for sale at 208 N Main Street with visibility and convenient access.

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Commercial Building on Highway 60
Commercial Building on Highway 60

300 W 1st Street, Hereford, TX 79045

$150,000

Commercial building in Hereford, TX, with high visibility.

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Hereford Commercial Land Opportunity
Hereford Commercial Land Opportunity

3955 US-60, Hereford, TX 79045

$550,000
10.00 AC lot

10-acre commercial lot in Hereford, TX, ready for development.

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Specialty Building with Chapel Area
Specialty Building with Chapel Area

411 E 6th Street, Hereford, TX 79045

$415,000

Versatile specialty facility featuring a large chapel area plus office, break room, and substantial storage.

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Metal Shop Building with Office
Metal Shop Building with Office

3994 County Road 7, Hereford, TX 79045

$220,000
1.22 AC lot

Metal 40-by-60 shop includes office space, four overhead doors, an overhead crane, and fenced yard on 1.22 acres.

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Hereford, TX Commercial Land
Hereford, TX Commercial Land

3955 U.S. 60, Hereford, TX 79045

$550,000
10.00 AC lot

10 acre commercial lot ready for construction in Hereford, TX.

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Fitness Center with Absolute NNN Lease
Fitness Center with Absolute NNN Lease

301 Main Street, Hereford, TX 79045

Contact for pricing
6,972 sqft

Anytime Fitness operates a 6,972 SF facility under an absolute NNN lease with zero landlord responsibility for operating or capital expenses.

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Land For Sale, Hereford, TX
Land For Sale, Hereford, TX

402 W Gracy Street, Hereford, TX 79045

$35,000

Commercial land available in Hereford, Texas.

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Deaf Smith County, TX Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Deaf Smith County, TX, showcased through 31 active listings on our real estate platform. These investment opportunities span a total of 77,454 square feet of properties for sale, with an estimated market value of $5,276,800.

Sale prices for business properties in Deaf Smith County, TX start at $140,500, averaging $376,914, and reaching up to $700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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