Yankton County, SD Commercial Real Estate for Sale

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Veterinary Medical Center with Boarding
Updated: Aug 15, 2025
Veterinary Medical Center with Boarding

1603 Broadway Ave, Yankton, SD 57078

$999,900
3,480 sqft 0.31 AC lot
3,480‑square‑foot veterinary facility on 0.31 acres
Includes veterinary clinic, grooming, and boarding functions
Supports care for both small and large animals
Up to 13 off‑street parking spaces plus 6+ on‑street employee spaces
B2 Highway Business zoning
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Multi-Building Truck Terminal
Updated: May 19
Multi-Building Truck Terminal

30844 447 Ave., Mission Hill, SD 57046

$975,000
14.78 AC lot
14.78‑acre commercial tract near Mission Hill, east of Yankton
44' x 104' Morton Building
30' x 60' storage building and wood shop
40' x 50' west shop
Modern ranch‑style modular home constructed in 2006
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Neighborhood Convenience Store
Neighborhood Convenience Store

300 W 23rd St., Yankton, SD 57078

$495,000
0.92 AC lot

Business sale includes branded fuel, a dedicated video lottery area, and an off-sale liquor license.

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Restaurant and Bar with Off-Street Parking
Restaurant and Bar with Off-Street Parking

44368 309 St, Mission Hill, SD 57046

$385,000
2,400 sqft 0.50 AC lot

Established restaurant and bar with indoor dining, bar service, and ample off-street parking on a half-acre lot.

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Flex Industrial Property With Truck Access
Flex Industrial Property With Truck Access

3704 E SD Hwy 50, Yankton, SD 57078

$1,195,000
11.99 AC lot

Industrial facility combines manufacturing, storage, office, and repair-shop areas.

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Steel Flex Warehouse Condo
Steel Flex Warehouse Condo

4003 W 8th, Yankton, SD 57078

$126,900

Steel flex warehouse unit includes insulated interior, an insulated overhead door, and a private restroom.

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Broadway Retail/Office Space
Broadway Retail/Office Space

821 Broadway Ave, Yankton, SD 57078

$270,000
2,000 sqft

2,000 SF commercial space with storefront windows and a flexible floorplan, suited for retail, office, or service use.

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Turnkey Veterinary Facility
Turnkey Veterinary Facility

1603 Broadway Ave, Yankton, SD 57078

$999,900
3,480 sqft

Turnkey veterinary operation with grooming and boarding setup, plus parking for customers and employees.

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Industrial Truck Terminal Property
Industrial Truck Terminal Property

30844 447 Ave., Mission Hill, SD 57046

$975,000
14.78 AC lot

Rural industrial site with three large buildings, including a Morton building and storage/shops, plus a surrounding storage drop yard.

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Arby's Absolute NNN Restaurant
Arby's Absolute NNN Restaurant

3009 Broadway Ave, Yankton, SD 57078

Contact for pricing
1.12 AC lot

Brand-new 20-year absolute NNN Arby’s lease with 5% escalations every five years on a Walmart pad site.

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Industrial Warehouse with Mezzanine
Industrial Warehouse with Mezzanine

601 Archery Ln, Yankton, SD 57078

Contact for pricing
9,600 sqft

I-9 Industrial zoning, three-phase power, and loading infrastructure support a range of warehouse and industrial operations.

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Industrial Zoned Corner Land
Industrial Zoned Corner Land

114 Mulberry Street, Yankton, SD 57078

$200,000
0.25 AC lot

0.25-acre industrial-zoned corner lot with city utilities and street access in Yankton city limits.

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Ranch Estate with Horse Barn
Ranch Estate with Horse Barn

30386 438th Ave, Yankton, SD 57078

Contact for pricing
5,000 sqft 77.87 AC lot

Ranch-style home on rolling pasture with a horse/calving barn, machine shed, and multiple livestock shelters.

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Turn-Key Bar and Grill Restaurant
Turn-Key Bar and Grill Restaurant

300 Lincoln Ave, Volin, SD 57072

$215,000

Restaurant and bar with updated kitchen equipment and efficient layout, offered as a turn-key opportunity.

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Agricultural Hunting Tract with Shed
Agricultural Hunting Tract with Shed

30862 456th Ave, Volin, SD 57072

Contact for pricing
2,880 sqft 18.00 AC lot

18 acres of rural land with a wood frame machine shed, rural water, and view-ready build location.

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Regional Bank NNN Investment
Regional Bank NNN Investment

2408 N Broadway Ave, Yankton, SD 57078

Contact for pricing
4,988 sqft

Single-tenant NNN bank property on a major road, with a regional bank tenant in place.

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Based on your search, we've compiled 72 Potential Opportunities for your consideration. Besides 16 Active listings in Yankton County, SD, we suggest exploring several alternatives: similar 56 Off-Market properties to explore as potential leads

Off-Market Properties in Yankton County, SD

Consider similar Off-Market properties in Yankton County, SD. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

420 Broadway Ave
OFFICE BUILDING

420 Broadway Ave, Yankton, SD 57078-4305

$240,000
Estimated value
2,640 sqft 0.15 AC lot
View details
200 3rd St
RETAIL STORES (PERSONAL SERVICES)

200 3rd St, Yankton, SD 57078-4323

$295,000
Estimated value
4,166 sqft 0.05 AC lot
View details
805 Smt St
VACANT COMMERCIAL LAND

805 Smt St, Yankton, SD 57078-3338

$90,000
Estimated value
0.23 AC lot
View details
1001 9th St
RETAIL STORES (PERSONAL SERVICES)

1001 9th St, Yankton, SD 57078-3309

$220,000
Estimated value
2,692 sqft 0.41 AC lot
View details
3111 Shipton Rd
WAREHOUSE, STORAGE

3111 Shipton Rd, Yankton, SD 57078-8002

$365,000
Estimated value
11,200 sqft 9.42 AC lot
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Yankton, SD 57078
VACANT COMMERCIAL LAND

Yankton, SD 57078

$1,600,000
Estimated value
4.79 AC lot
View details
Gayville, SD 57031
WAREHOUSE, STORAGE

Gayville, SD 57031

$200,000
Estimated value
2,156 sqft 0.70 AC lot
View details
29741 452nd Ave
COMMERCIAL (GENERAL)

29741 452nd Ave, Irene, SD 57037-5722

$50,000
Estimated value
0.83 AC lot
View details

Yankton County, SD Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Yankton County, SD, showcased through 16 active listings on our real estate platform. These investment opportunities span a total of 33,828 square feet of properties for sale, with an estimated market value of $6,836,700.

Sale prices for business properties in Yankton County, SD start at $126,900, averaging $621,518, and reaching up to $1,195,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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