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    Middlesex, PA
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    45 results
    Carlisle Land For Sale
    $275,000
    1.78 Acres

    Carlisle Land For Sale

    624 ALEXANDER SPRING RD, Carlisle, PA 17015

    1.78-acre mixed-use lot near I-81 in Carlisle, PA.

    • 1.78‑acre Mixed‑Use (MU) lot
    • Less than 1 mile from I‑81
    • Flexible zoning permits a wide range of uses
    • Permitted uses include professional and medical offices
    • Permitted uses include retail and personal services
    Updated: Mar 3
    View details
    Turnkey Distillery, Bar & Restaurant
    $995,000
    6,381 SF

    Turnkey Distillery, Bar & Restaurant

    137 N Hanover St, Carlisle, PA 17013

    Fully renovated distillery, bar, and restaurant in downtown Carlisle.

    • Turnkey distillery, bar, and restaurant: Includes all furniture, fixtures, and equipment (FF&E) for immediate operation.
    • Fully equipped production facility: Designed for on‑site spirit distilling.
    • Prime location in downtown Carlisle's shopping district.
    • High‑traffic area: Close proximity to Carlisle Fairgrounds, attracting over 500,000 annual visitors.
    • Completely renovated in 2019.
    Updated: Nov 21, 2025
    View details
    Restaurant and Motel with License
    $1,250,000
    8,064 SF

    Restaurant and Motel with License

    Established restaurant and motel with liquor license for sale.

    1582 Holly Pike, Carlisle, PA 17015
    View details
    Carlisle Medical Office Building For Sale
    $2,700,000
    11,301 SF

    Carlisle Medical Office Building For Sale

    11,301 SF medical office building in Carlisle, Pennsylvania.

    27 Brookwood Ave, Carlisle, PA 17015
    View details
    Commercial Lot on High-Traffic Corner
    $460,000
    1,762 SF

    Commercial Lot on High-Traffic Corner

    0.51 acre lot with commercial zoning and high visibility.

    35 Cavalry Road, Carlisle, PA 17013
    View details
    Truck Towing and Recovery Portfolio
    $14,200,000
    46,000 SF

    Truck Towing and Recovery Portfolio

    Portfolio of truck towing and recovery facilities in Pennsylvania for sale.

    1220 Newville Road, Carlisle, PA 17013
    View details
    Renovated Office Space Available Now
    Contact for pricing
    10,000 SF

    Renovated Office Space Available Now

    Newly renovated office space available for sublease near UPMC Hospital.

    3 Jennifer Ct, Carlisle, PA 17015
    View details
    Carlisle Historic District Commercial Space
    $950,000
    13,000 SF

    Carlisle Historic District Commercial Space

    13,000+ SF commercial space in Carlisle's Historic District.

    142 North Hanover Street, Carlisle, PA 17013
    View details
    Planet Fitness Anchored Retail Center
    $3,695,000
    23,584 SF

    Planet Fitness Anchored Retail Center

    NNN leased retail center anchored by Planet Fitness and UPMC.

    1186 Walnut Bottom Road |, Carlisle, PA 17015
    View details
    Land Parcel Near I-81
    $750,000

    Land Parcel Near I-81

    1.66 acre commercial land with highway access and frontage.

    I-81 and W. Trindle Road, Carlisle, PA 17013
    View details
    Medical/General Office Near UPMC Hospital
    Contact for pricing
    16,000 SF

    Medical/General Office Near UPMC Hospital

    16,000 SF medical/general office space for sale near UPMC.

    3 Alexandra Court, Carlisle, PA 17015
    View details
    Carlisle Agricultural Property for Sale
    $1,899,900
    1,836 SF

    Carlisle Agricultural Property for Sale

    Agricultural property located 4.5 miles south of Carlisle square.

    67 E Yellowbreeches Rd, Carlisle, PA 17015
    View details
    Operating Car Wash with Apartments
    $1,575,000
    4,402 SF

    Operating Car Wash with Apartments

    Car wash with self-serve bays and apartment building.

    400 S Hanover St, Carlisle, PA 17013
    View details
    Commercial Land on Spring Road
    $480,000
    1.06 Acres

    Commercial Land on Spring Road

    One-acre commercial property with high visibility and multiple access points.

    1602 SPRING ROAD, Carlisle, PA 17013
    View details
    Prime Commercial Land for Sale
    Contact for pricing

    Prime Commercial Land for Sale

    11.71 acre commercial parcel with redevelopment potential in Carlisle, PA.

    800 East High Street, Carlisle, PA 17013
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    Prime Commercial Land For Sale
    $750,000
    1.63 Acres

    Prime Commercial Land For Sale

    1.63 acre commercial land with highway frontage and high traffic.

    1900 W Trindle Rd, Carlisle, PA
    View details
    Carlisle Borough Free-Standing Building
    $189,000
    2,930 SF

    Carlisle Borough Free-Standing Building

    Two-story concrete building with parking in Carlisle Borough.

    254 E North St, Carlisle, PA 17013
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    Commercial Land on Route 11
    $3,500,000

    Commercial Land on Route 11

    12.79 acres of commercial land on heavily traveled Route 11.

    Carlisle, PA 17013
    View details
    21.92 Acres Commercial Land
    $1,750,000

    21.92 Acres Commercial Land

    Commercial land near major highways, ideal for various businesses.

    NEQ US Route 11 and PA Turnpike, Carlisle, PA 17013
    View details
    Carlisle Mixed-Use Development Opportunity
    $275,000
    1.78 Acres

    Carlisle Mixed-Use Development Opportunity

    1.78-acre lot near I-81, suitable for diverse development.

    624 Alexander Spring Rd, Carlisle, PA 17015
    View details
    Carlisle PA Pad Site Available
    Contact for pricing

    Carlisle PA Pad Site Available

    Pad site for ground lease in Carlisle, Pennsylvania.

    226 Westminster Drive (#188), Carlisle, PA 17013
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    5.73 Acres at Signalized Intersection
    $3,500,000
    1.71 Acres

    5.73 Acres at Signalized Intersection

    Commercial and residential land for sale at signalized intersection.

    1310-1312 HOLLY PIKE, Carlisle, PA 17013
    View details
    Carlisle Industrial Outdoor Storage Facility
    Contact for pricing
    20,000 SF

    Carlisle Industrial Outdoor Storage Facility

    20,000 SF turn-key industrial facility for sale or lease.

    1511 Commerce Ave, Carlisle, PA
    View details
    1.43 Acre Storage Unit Lot
    $225,000
    1.42 Acres

    1.43 Acre Storage Unit Lot

    1.43 acre lot with preliminary approval for storage units.

    3101 SPRING ROAD, Carlisle, PA 17013
    View details

    Middlesex, PA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 48 commercial real estate for sale in Middlesex, PA, showcased through 45 active listings on our real estate platform. These investment opportunities span a total of 163,352 square feet of properties for sale, with an estimated market value of $49,301,800.

    Sale prices for business properties in Middlesex, PA start at $189,000, averaging $2,465,090, and reaching up to $14,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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