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    Portsmouth, OH Commercial Real Estate for Sale

    15 results
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    Historic Theater and Event Venue
    $900,000
    8,243 SF

    Historic Theater and Event Venue

    832 Gallia St, Portsmouth, OH 45662

    Fully operational entertainment venue in downtown Portsmouth, Ohio.

    • Fully operational, revenue‑generating entertainment venue with strong brand recognition.
    • High capacity (up to 1150 patrons) suitable for diverse events.
    • Three bars and VIP seating enhance the event experience.
    • State‑of‑the‑art lighting and sound systems are already in place.
    • Flexible seating/standing configurations accommodate various event types.
    Updated: Oct 20, 2025
    View details
    Commercial Building in Boneyfiddle District
    $429,000
    4,961 SF

    Commercial Building in Boneyfiddle District

    628 3Rd St, Portsmouth, OH 45662

    Commercial building with multiple spaces and courtyard in Portsmouth, OH.

    • Large commercial building in the Boneyfiddle District.
    • Multiple commercial spaces.
    • Courtyard spaces for additional usages.
    • Brick construction.
    • Central air cooling.
    Updated: Dec 1, 2025
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    Downtown Portsmouth Commercial Building For Sale
    $525,000
    5,526 SF

    Downtown Portsmouth Commercial Building For Sale

    High-visibility commercial building with development potential in historic downtown Portsmouth.

    317 Chillicothe St, Portsmouth, OH 45662
    View details
    Furnished Office Space Available
    Contact for pricing
    0.11 Acres

    Furnished Office Space Available

    Furnished office space with utilities and amenities included.

    613 Chillicothe St, Portsmouth, OH 45662
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    Versatile Mixed-Use Commercial Property
    $274,500
    2,208 SF

    Versatile Mixed-Use Commercial Property

    High-visibility commercial property with versatile layout and living space.

    826 Gay St, Portsmouth, OH 45662
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    Commercial Property with Multiple Buildings
    $600,000
    1,432 SF

    Commercial Property with Multiple Buildings

    Versatile commercial property featuring auto shop, car wash, and apartments.

    2629 Scioto Trl, Portsmouth, OH 45662
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    Versatile Property in Clay Township
    $199,000
    8,832 SF

    Versatile Property in Clay Township

    Multi-use property with sanctuary, hall, duplex, and ample parking.

    1313 Rosemount Rd, Portsmouth, OH 45662
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    Transformed Church Building with Potential
    $399,000
    26,000 SF

    Transformed Church Building with Potential

    Remarkable 26,000 SF church with adaptable layout and potential.

    1601 Harrisonville Ave, Portsmouth, OH 45662
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    Commercial Building with Large Parking
    $179,000
    2,650 SF

    Commercial Building with Large Parking

    Commercial building with parking lot, endless possibilities in Portsmouth, OH.

    1016 Clay St, Portsmouth, OH 45562
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    Automatic Touchless Car Wash Facility
    $380,000
    1,440 SF

    Automatic Touchless Car Wash Facility

    24-hour automatic touchless car wash with vacuum stations.

    2715 Scioto Trl, Portsmouth, OH 45662
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    Commercial Building in Boneyfiddle District
    $699,000
    6,515 SF

    Commercial Building in Boneyfiddle District

    Commercial building with multiple spaces and garage in Portsmouth, OH.

    618 3Rd St, Portsmouth, OH 45662
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    Commercial Building in Portsmouth, OH
    $199,000
    1,288 SF

    Commercial Building in Portsmouth, OH

    Commercial property suitable for medical or office use in Portsmouth.

    2002 Robinson Ave, Portsmouth, OH 45662
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    Prime Portsmouth OH Land
    $380,000
    0.38 Acres

    Prime Portsmouth OH Land

    0.38-acre lot, ideal for development.

    2715 Scioto Trl, Portsmouth, OH 45662
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    Portsmouth Car Wash - Owner/User
    $380,000
    1,440 SF

    Portsmouth Car Wash - Owner/User

    Profitable Flex Space, 1440 SF, Ohio

    2715 Scioto Trl, Portsmouth, OH 45662
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    Portsmouth QSR Investment Opportunity
    $2,549,000
    0.40 Acres

    Portsmouth QSR Investment Opportunity

    High-traffic KFC & Taco Bell, 15+ years remaining

    0 Us-23, Portsmouth, OH undefined
    View details
    Based on your search, we've compiled 2413 Potential Opportunities for your consideration. Besides 15 Active listings in Portsmouth, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2393 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Jade East Restaurant For Sale
    $450,000
    2,400 SF

    Jade East Restaurant For Sale

    Well-known restaurant in New Boston, OH with great potential.

    3556 Rhodes Ave, New Boston, OH 45662
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    Retail Property in New Boston, OH
    $450,000
    11,300 SF

    Retail Property in New Boston, OH

    11,300 SF retail space on 0.7022 acres for sale.

    3972 Gallia St, New Boston, OH 45662
    View details
    Wheelersburg Commercial Building For Sale
    $799,000
    2,400 SF

    Wheelersburg Commercial Building For Sale

    High-visibility commercial building in Wheelersburg, suitable for various business types.

    8806 Ohio River Rd, Wheelersburg, OH 45694
    View details
    Wheelersburg Commercial Building with Rentals
    $1,300,000
    14,265 SF

    Wheelersburg Commercial Building with Rentals

    Commercial building with offices, apartments, Airbnb, and medical facilities.

    11826 Gallia Pike, Wheelersburg, OH 45694
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Portsmouth, OH
    $99,999
    0.76 Acres

    Commercial Land in Portsmouth, OH

    0.758 acres of commercial land for sale.

    3624 Us 23, Portsmouth, OH 45662
    View details

    Explore Off-Market Properties in Portsmouth, OH

    Consider similar Off-Market properties in Portsmouth, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Us-23

    Us-23

    Restaurants • 0.40 Acres
    Value Estimation by Request
    0 Us-23, Portsmouth, OH undefined
    View details
    2912 Walnut St

    2912 Walnut St

    MINI-WAREHOUSE, STORAGE • 0.04 Acres
    Value Estimation
    $1,425,000
    2912 Walnut St, Portsmouth, OH 45662-4828
    View details
    6476 Gallia St

    6476 Gallia St

    MINI-WAREHOUSE, STORAGE • 0.14 Acres
    Value Estimation by Request
    6476 Gallia St, Portsmouth, OH 45662
    View details
    1826 8th St

    1826 8th St

    MINI-WAREHOUSE, STORAGE • 0.08 Acres
    Value Estimation by Request
    1826 8th St, Portsmouth, OH 45662
    View details
    2204 Gallia St

    2204 Gallia St

    MINI-WAREHOUSE, STORAGE • 0.31 Acres
    Value Estimation by Request
    2204 Gallia St, Portsmouth, OH 45662-4761
    View details
    2240 6th St

    2240 6th St

    FOOD PACKING, PACKING PLANT • 0.58 Acres
    Value Estimation
    $345,000
    2240 6th St, Portsmouth, OH 45662-4787
    View details
    2926 Walnut St

    2926 Walnut St

    MINI-WAREHOUSE, STORAGE • 0.12 Acres
    Value Estimation
    $625,000
    2926 Walnut St, Portsmouth, OH 45662
    View details
    2920 Walnut St

    2920 Walnut St

    MINI-WAREHOUSE, STORAGE • 0.07 Acres
    Value Estimation
    $1,440,000
    2920 Walnut St, Portsmouth, OH 45662
    View details
    2335 Charles St

    2335 Charles St

    MINI-WAREHOUSE, STORAGE • 1.37 Acres
    Value Estimation
    $595,000
    2335 Charles St, Portsmouth, OH 45662
    View details

    Portsmouth, OH Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1690 commercial real estate investment opportunities in Portsmouth, OH with 15 listings featured on our commercial real estate marketplace. The current inventory includes 38,629,204 square feet of properties with an estimated value of $250,634,398.

    Estimated prices for commercial real estate in Portsmouth, OH begin at $30,000, with an average of $349,559 and extend to $9,945,000.

    In Portsmouth, OH, current investment values show:

    • Retail properties positioned at $353,654
    • Other commercial real estate measuring $349,422
    • Individual retail properties assessed at $269,472
    • Retail space calculated at $269,245
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    Browse Commercial real estate for Sale Near Portsmouth, OH

    Popular Searches in Portsmouth, OH

    Most Searched ZIP Codes in Portsmouth, OH

    • 45662
    • 45562
    • 45663

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