East Palestine, OH Commercial Real Estate for Sale

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Medical Office Building with Parking
Updated: Jul 23
Medical Office Building with Parking

151 N Walnut St, East Palestine, OH 44413

Contact for pricing
1,138 sqft
1138 SF two‑story building previously used as a doctor’s office
Main level includes waiting area, 2 exam rooms, and a half bath
Second floor has two rooms plus a partial/“sort of” bathroom setup
Partial basement with gravel floor and block/stone foundation
Furnace installed this past winter and includes A/C
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Downtown Retail Storefront
Updated: Jul 29, 2025
Downtown Retail Storefront

125 E Taggart St, East Palestine, OH 44413

Contact for pricing
8,200 sqft
Former dollar store with large, wide open retail space
Located in downtown East Palestine, close to Market St
On‑site parking
Street signage
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Skerball Building: Mixed-Use Potential
Skerball Building: Mixed-Use Potential

55 N Market Street, East Palestine, OH 44413

Contact for pricing
12,000 sqft 0.10 AC lot

Two-story building in East Palestine's business district.

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See what stands out in Columbiana County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

Cap Rate available after sign in
NOI available after sign in
Local Demand available after sign in
East Palestine Corner Commercial Building
East Palestine Corner Commercial Building

15 S Market Street, East Palestine, OH 44413

Contact for pricing

One-story building at a busy intersection in East Palestine, OH.

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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 4 Active listings in East Palestine, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 68 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Brick Retail Building
Brick Retail Building

Darlington, PA 16115

$295,000
0.79 AC lot

Commercial building with on-site parking in a country setting.

View details
Medical Office Building with Basement
Medical Office Building with Basement

750 E Park Ave, Columbiana, OH 44408

Contact for pricing
18,722 sqft

Well maintained two-level medical building with a full basement, sited on more than six acres.

View details
Agricultural Land with Residence
Agricultural Land with Residence

4025 Constitution Blvd, Darlington, PA 16115

$450,000

Mixed-zoning acreage includes an updated manufactured residence, detached garage, private lane, and space for agricultural or recreational use.

View details
Columbiana Cleared Farmland for Sale
Columbiana Cleared Farmland for Sale

42059 OH-344, Columbiana, OH

Contact for pricing
42.50 AC lot

42.5 acres of cleared farmland zoned for industrial use.

View details

Off-Market Properties in East Palestine, OH

Consider similar Off-Market properties in East Palestine, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

90 Market St
RESTAURANT

90 Market St, East Palestine, OH 44413-2054

Estimated value:
$155,000
4,660 sqft 0.14 AC lot
View details
2113 State Rte 170
COMMERCIAL (GENERAL)

2113 State Rte 170, East Palestine, OH 44413-8768

Estimated value:
$115,000
3.59 AC lot
View details
25 Main St
RETAIL STORES (PERSONAL SERVICES)

25 Main St, East Palestine, OH 44413-1824

Estimated value:
$115,000
560 sqft 0.07 AC lot
View details
40 Taggart St
RESTAURANT

40 Taggart St, East Palestine, OH 44413-2048

Estimated value:
$90,000
2,520 sqft 0.06 AC lot
View details
38 Main St
COMMERCIAL (GENERAL)

38 Main St, East Palestine, OH 44413-2034

Estimated value:
$55,000
1,472 sqft 0.14 AC lot
View details
139 Walnut St
MEDICAL BUILDING

139 Walnut St, East Palestine, OH 44413-1815

Estimated value:
$260,000
3,582 sqft 0.20 AC lot
View details
49 Taggart St
RESTAURANT

49 Taggart St, East Palestine, OH 44413-2047

Estimated value:
$65,000
2,100 sqft 0.07 AC lot
View details
96 Market St
RETAIL STORES (PERSONAL SERVICES)

96 Market St, East Palestine, OH 44413-2054

Estimated value:
$65,000
1,360 sqft 0.05 AC lot
View details
50321 State Rte 14
COMMERCIAL (GENERAL)

50321 State Rte 14, East Palestine, OH 44413-1026

Estimated value:
$275,000
1,640 sqft 5.64 AC lot
View details
31 Market St
OFFICE BUILDING

31 Market St, East Palestine, OH 44413-2053

Estimated value:
$80,000
4,000 sqft 0.05 AC lot
View details
102 Market St
RETAIL STORES (PERSONAL SERVICES)

102 Market St, East Palestine, OH 44413-2056

Estimated value:
$155,000
3,309 sqft 0.09 AC lot
View details
Taggart St
VACANT COMMERCIAL LAND

Taggart St, East Palestine, OH 44413

Estimated value:
$245,000
0.67 AC lot
View details
65-67 Market N St
RETAIL STORES (PERSONAL SERVICES)

65-67 Market N St, East Palestine, OH 44413

Estimated value:
$130,000
3,720 sqft 0.08 AC lot
View details
50600 State Rte 14
RETAIL STORES (PERSONAL SERVICES)

50600 State Rte 14, East Palestine, OH 44413-8754

Estimated value:
$85,000
9,552 sqft 1.42 AC lot
View details
51022 State Rte 14
VACANT COMMERCIAL LAND

51022 State Rte 14, East Palestine, OH 44413-9747

Estimated value:
$85,000
1.37 AC lot
View details
14 Sr
VACANT COMMERCIAL LAND

14 Sr, East Palestine, OH 44413

Estimated value:
$85,000
1.48 AC lot
View details
14 Sr
COMMERCIAL (GENERAL)

14 Sr, East Palestine, OH 44413

Estimated value:
$1,240,000
17.27 AC lot
View details
49995 State Rte 14
RETAIL STORES (PERSONAL SERVICES)

49995 State Rte 14, East Palestine, OH 44413-1077

Estimated value:
$150,000
1,680 sqft 1.70 AC lot
View details
190 Market St
RETAIL STORES (PERSONAL SERVICES)

190 Market St, East Palestine, OH 44413-2019

Estimated value:
$390,000
3,000 sqft 0.28 AC lot
View details
Clark W St
PARKING GARAGE, PARKING STRUCTURE

Clark W St, East Palestine, OH 44413

Estimated value:
$235,000
0.16 AC lot
View details

East Palestine, OH Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in East Palestine, OH, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 21,338 square feet of properties for sale.

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Demographics Overview

Population 7,329
Population Growth (5Y) -0.6%
Median Household Income $51,071
College Educated 10.4%

Taxes & Financing

Tax Rate (average for all types) 3.71%
Property Tax per SF $58.45 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Columbiana County

New Delisted

Total CRE Inventory on Market (SF)

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