Osceola, MO Commercial Real Estate for Sale

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Wedding Venue With Four Living Spaces
Updated: Oct 31, 2025
Wedding Venue With Four Living Spaces

2105 NE 315 Pvt Road, Osceola, MO 64776

$1,900,000
52.10 AC lot
52.1‑acre property with a dedicated wedding and event venue
Four separate living spaces, including a three‑bedroom main home and two cabins
Venue includes full kitchen, laundry equipment, storage, dressing areas, and two‑stall men’s and women’s restrooms
Covered patio and deck overlook a stocked pond supplied by an artesian well
One 40x16 cabin was built in 2017 and includes 2 bedrooms, 1 bath, and a side deck
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Historic Mixed-Use Building
Updated: Jul 18
Historic Mixed-Use Building

720 Second Street, Osceola, MO 64776

$50,000
0.07 AC lot
1902 construction with many original architectural details retained
0.07‑acre downtown commercial property
Potential configurations include professional office, retail, and mixed‑use development
Located near local businesses and the St. Clair County Courthouse
Second Street location in Osceola, MO
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Agricultural Land with Creek
Agricultural Land with Creek

3665 NW Center Road, Osceola, MO 64776

$320,000
40.00 AC lot

Pasture, timber, an all-weather access road, and existing well and septic infrastructure support varied rural land uses.

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Turnkey Cattle Pasture Property
Turnkey Cattle Pasture Property

2765 Se 75 Rd, Osceola, MO 64776

$2,100,000
1,316 sqft

Turnkey cattle operation featuring open pasture, multiple ponds and springs, and farm improvements across two nearby tracts.

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Bar & Grill with Lodge Rooms
Bar & Grill with Lodge Rooms

1315 SW Pence Avenue, Osceola, MO 64776

$89,900
4,344 sqft 1.17 AC lot

Vacant bar and grill with four on-site lodge rooms, positioned on 1.17 acres near Truman Lake recreation access.

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LAND - Osceola, MO
LAND - Osceola, MO

Tract 2 / 3665 NW Center Road, Osceola, MO 64776

$240,000
40.00 AC lot

Agricultural land / Farmland · 40.00 Acres

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Wedding Venue Estate with Cabins
Wedding Venue Estate with Cabins

2105 Ne 315 Pvt Road, Osceola, MO 64776

$1,900,000

Wedding venue on a 50+ acre bluff estate with multiple residences, cabins, and a stocked pond event area.

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Recreational Hunting Farm Acreage
Recreational Hunting Farm Acreage

0000 NE Hwy ZZ, Osceola, MO 64740

Contact for pricing
3,000 sqft

Rural property with a 50-by-60 pole barn, multiple ponds, and a certified lagoon system.

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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 8 Active listings in Osceola, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 64 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Flex Space Building with Office and HVAC
Flex Space Building with Office and HVAC

57 SE 1100 Road, Deepwater, MO 64740

$398,000
5.10 AC lot

Flex space on 5.1 acres with office, bathroom with septic system, electric HVAC, and backup propane heat.

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Highway 13 Storage Facility
Highway 13 Storage Facility

61 SE 1100, Deepwater, MO 64740

Contact for pricing
16,000 sqft 4.00 AC lot

16,000+ sq ft storage facility on 4 acres.

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Hunting Land with One-Bedroom Cabin
Hunting Land with One-Bedroom Cabin

000 Se Highway J, Collins, MO 64738

$935,000
640 sqft 210.00 AC lot

Secluded hunting tract with a one-bedroom cabin, metal shed, mostly fenced acreage, and timbered hills plus grass pastures.

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Waterfront Land with River Frontage and Barn
Waterfront Land with River Frontage and Barn

SE 800 Rd., Collins, MO 64738

$70,000
5.95 AC lot

5.95-acre Sac River tract with 307+ feet of direct frontage, electric and fiber on site, plus a 60x40 barn.

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Off-Market Properties in Osceola, MO

Consider similar Off-Market properties in Osceola, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

3699 Hwy 13
RESTAURANT

3699 Hwy 13, Osceola, MO 64776-2421

Value Estimation by Request
5,120 sqft 6.10 AC lot
View details
3395 Old Hwy 13
COMMERCIAL (GENERAL)

3395 Old Hwy 13, Osceola, MO 64776-2416

Value Estimation by Request
1.50 AC lot
View details
245 Pne St
RETAIL STORES (PERSONAL SERVICES)

245 Pne St, Osceola, MO 64776-7466

Value Estimation by Request
2,059 sqft
View details
7110 Hwy 13th, Unit 13
RETAIL STORES (PERSONAL SERVICES)

7110 Hwy 13th, Osceola, MO 64776-6291

Unit 13
Value Estimation by Request
8,400 sqft 9.93 AC lot
View details
12480 Hwy 82
THEATER (MOVIE)

12480 Hwy 82, Osceola, MO 64776-2663

Value Estimation by Request
7,316 sqft 3.04 AC lot
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115 Libby St
RETAIL STORES (PERSONAL SERVICES)

115 Libby St, Osceola, MO 64776-2512

Value Estimation by Request
12,000 sqft 7.62 AC lot
View details
635 3rd St
VACANT COMMERCIAL LAND

635 3rd St, Osceola, MO 64776

Value Estimation by Request
View details
740 2nd St
RETAIL STORES (PERSONAL SERVICES)

740 2nd St, Osceola, MO 64776

Value Estimation by Request
1,900 sqft
View details
215 Pne St
VACANT COMMERCIAL LAND

215 Pne St, Osceola, MO 64776-7466

Value Estimation by Request
View details
215 Pne St
SERVICE STATION (FULL SERVICE)

215 Pne St, Osceola, MO 64776-7466

Value Estimation by Request
240 sqft
View details
205 Locust St
OFFICE BUILDING

205 Locust St, Osceola, MO 64776-9304

Value Estimation by Request
966 sqft
View details
381 467th Rd
COMMERCIAL (GENERAL)

381 467th Rd, Osceola, MO 64776

Value Estimation by Request
21.60 AC lot
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720 2nd St
OFFICE BUILDING

720 2nd St, Osceola, MO 64776

Value Estimation by Request
2,400 sqft
View details
475 Hailman Rd
RETAIL STORES (PERSONAL SERVICES)

475 Hailman Rd, Osceola, MO 64776-9563

Value Estimation by Request
1,280 sqft 0.30 AC lot
View details
320 Pne St
VACANT COMMERCIAL LAND

320 Pne St, Osceola, MO 64776

Value Estimation by Request
View details
625 Pne St 3rd St
VACANT COMMERCIAL LAND

625 Pne St 3rd St, Osceola, MO 64776

Value Estimation by Request
View details

Osceola, MO Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Osceola, MO, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 8,660 square feet of properties for sale, with an estimated market value of $6,599,900.

Sale prices for business properties in Osceola, MO start at $50,000, averaging $942,842, and reaching up to $2,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 3,355
Population Growth (5Y) -14.2%
Median Household Income $43,461
College Educated 7.3%

High-Yield Neighborhoods for Investment

Identify Osceola submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
64776 $1.5M

Taxes & Financing

Tax Rate (average for all types) 6.11%
Property Tax per SF $58.93 per SF
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in St. Clair County

New Delisted

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