Isabella County, MI Commercial Real Estate for Sale

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83 properties
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Medical Office Building with Basement
Updated: May 28
Medical Office Building with Basement

520 N Mission Street, Mt Pleasant, MI 48858

$775,000
9,050 sqft · 0.88 AC lot
Medical office currently in use; former Texan Restaurant
4050 SF building with a 12' basement
Large parking lot in front and behind with on‑site parking lot
Asphalt roof with exterior of wood and brick and frame construction
Approved for cannabis location
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Medical Office Building with Waterfront Entry
Updated: May 28
Medical Office Building with Waterfront Entry

3520 N Woodruff Road, Weidman, MI 48893

$246,000
3,465 sqft · 1.29 AC lot
Medical facility/commercial building with 21 rooms, including 4 fully equipped exam rooms plus procedure, lab, and X‑ray rooms
Welcoming lobby and reception area with expansive glass entryway and waterfront views over Weidman Pond
10,000 SF asphalt parking lot and fully handicap accessible layout
Includes physician office, two mid‑level provider offices, records room, spacious break room, and 3 bathrooms
Second‑floor insulated dry storage area houses HVAC systems for additional operational and storage space
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Multi-Tenant Executive Office Building
Multi-Tenant Executive Office Building

1205 S Mission Street, Mt Pleasant, MI 48858

$865,000
13,586 sqft · 0.80 AC lot

Multi-tenant office building with 27 suites, including leased medical and professional offices and updated HVAC and lighting.

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Commercial Property with Liquor License
Commercial Property with Liquor License

1750 N Littlefield Road, Weidman, MI 48893

$299,000
3,220 sqft · 0.89 AC lot

Turnkey commercial property with beer, wine, and liquor license.

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Downtown Office Building with Basement
Downtown Office Building with Basement

209 E Broadway Street, Mt Pleasant, MI 48858

$219,000
2,605 sqft · 0.06 AC lot

Office building configured for multiple work areas, conference space, and a full basement in downtown Mt. Pleasant.

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Waterfront Commercial Land with Restaurants
Waterfront Commercial Land with Restaurants

506 W Broadway, Mt Pleasant, MI 48858

$1,500,000
10,327 sqft · 7.00 AC lot

Seven-acre riverfront parcel with existing restaurant operations between two parks near City Hall.

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Remodeled Downtown Mixed-Use Building
Remodeled Downtown Mixed-Use Building

309 W Michigan, Mt Pleasant, MI 48858

$215,000
2,002 sqft · 0.19 AC lot

Fully remodeled building with storefront frontage and flexible interior space for retail, office, or mixed-use needs.

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Downtown Office Building with Dual Entrances
Downtown Office Building with Dual Entrances

115 S Franklin, Mt Pleasant, MI 48858

$210,000
2,240 sqft · 0.05 AC lot

Office building configured for counseling and professional services, featuring two front entrances and convenient nearby parking.

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Industrial Warehouse with Office Space
Industrial Warehouse with Office Space

5776 Venture Way, Mt Pleasant, MI 48858

$550,000
7,000 sqft · 3.50 AC lot

Industrial warehouse includes shop/warehouse space, office area, multiple overhead doors, and a fenced storage yard.

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Freestanding Commercial Building with Parking
Freestanding Commercial Building with Parking

1506 W High, Mt Pleasant, MI 48858

$299,000
6,120 sqft · 0.50 AC lot

Freestanding 6,120 SF building on a half-acre lot with paved parking and CD-4 zoning for flexible commercial use.

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Former Bank Drive-Thru Building
Former Bank Drive-Thru Building

2015 S Mission Street, Mt Pleasant, MI 48858

$1,150,000
1,776 sqft · 1.03 AC lot

Former bank with drive-thru lanes and executive office space for businesses needing customer-friendly vehicle access.

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Versatile Commercial Space, Mt. Pleasant
Versatile Commercial Space, Mt. Pleasant

Mt Pleasant, MI 48858

$765,000
4,150 sqft

4,000+ sq ft commercial space near Soaring Eagle Casino.

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Two-Story Office Building with Elevator
Two-Story Office Building with Elevator

2600 Three Leaves Drive, Mt Pleasant, MI 48858

$2,100,000
24,000 sqft · 7.50 AC lot

Two-story commercial office building with elevator service and ample on-site parking for staff, patients, and visitors.

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Corner Restaurant Building with Apartment
Corner Restaurant Building with Apartment

20 E Remus Road, Mt Pleasant, MI 48858

$289,900
2,220 sqft · 1.96 AC lot

Freestanding corner property with a fully equipped commercial kitchen and an upstairs two-bedroom apartment.

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Turnkey Assisted Living and Residence
Turnkey Assisted Living and Residence

702 & 700 E Remus Road, Mt Pleasant, MI 48858

$1,350,000
8,264 sqft · 9.24 AC lot

Turnkey 12-bed assisted living plus a separate residence on wooded acreage, offered together for a full operating setup.

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Historic Mixed-Use Building
Historic Mixed-Use Building

323 W Wright Avenue, Shepherd, MI 48883

$489,000
5,200 sqft · 0.68 AC lot

For sale with operating retail and furnished short-term rentals plus parking and a vacant side lot.

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Office Building with Street Frontage
Office Building with Street Frontage

4906 E Pickard Street, Mount Pleasant, MI 48858

$279,900
1,467 sqft · 0.20 AC lot

Flexible office layout with multiple back areas, basement utility access, and prominent positioning on a high-traffic corridor.

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Commercial Land with Highway Frontage
Commercial Land with Highway Frontage

1740 & 1732 E Remus Road, Mt Pleasant, MI 48858

$269,000
1.80 AC lot

Zoned commercial with 298 feet of frontage on M-20 and utilities available, positioned in a high-traffic mixed-use area.

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Industrial Building with Loading Docks
Industrial Building with Loading Docks

711 W Pickard Street, Mt Pleasant, MI 48858

$2,900,000
142,076 sqft · 20.27 AC lot

Industrial multi-structure property offers loading docks and rail access in a flexible SD-I zoning district.

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Corner Specialty Property
Corner Specialty Property

300 S Mission Street, Mt Pleasant, MI 48858

$389,000
0.43 AC lot

For sale on S Mission Street with corner positioning for flexible specialty use on a 0.43-acre lot.

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Commercial Land with Apartments Above
Commercial Land with Apartments Above

309 W Broadway Street, Mt Pleasant, MI 48858

$389,000
0.35 AC lot

Vacant lot across from City Hall, zoned commercial with apartments above for potential mixed-use development.

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Corner-Lock Industrial Live/Work Building
Corner-Lock Industrial Live/Work Building

5496 W Isabella Road, Shepherd, MI 48883

$175,000
3,612 sqft · 0.84 AC lot

Industrial-style bay space with tall garage doors plus compact upstairs living quarters for a flexible live/work layout.

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Industrial Building with Acreage
Industrial Building with Acreage

Mount Pleasant, MI 48858

$550,000
7,000 sqft · 3.50 AC lot

Industrial building with shop, warehouse, office, and retail space.

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Vacant Commercial Land Lot
Vacant Commercial Land Lot

915 E Broomfield Road, Mt Pleasant, MI 48858

$300,000
0.56 AC lot

Vacant commercial lot in a high-traffic area with nearby access to an expressway.

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Isabella County, MI Commercial Real Estate Market Trends and Statistics

Explore 83 commercial real estate for sale in Isabella County, MI, showcased through 83 active listings on our real estate platform. These investment opportunities span a total of 668,528 square feet of properties for sale, with an estimated market value of $44,690,540.

Sale prices for business properties in Isabella County, MI start at $115,000, averaging $1,015,694, and reaching up to $6,570,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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