St Mary's County, MD Commercial Real Estate for Sale

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Medical Office Condominium
Updated: Jun 11
Medical Office Condominium

22888 THREE NOTCH Road, Lexington Park, MD 20653

$250,000
0.04 AC lot
1,582 SF +/- office condominium
2007 brick office building with tiled lobby and elevator
Open floor plan with coffee service bar and abundant natural light
ADA‑compliant restroom
Exposure to over 65,000 vehicles per day along MD Route 235
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Corner Commercial Land
Updated: Sep 4
Corner Commercial Land

29800 THREE NOTCH Road, Charlotte Hall, MD 20622

$2,200,000
3.30 AC lot
3.3‑acre cleared commercial parcel
TMX (Town Center Mixed Use) zoning
Corner site with access from Route 5 and Carpenter Lane
State entrance installed on Route 5; median crossover serves northbound and southbound traffic
Public water is accessible; recorded perc documentation and wet‑season testing status noted
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Commercial Land in Technology Park
Commercial Land in Technology Park

COTTONWOOD Parkway, California, MD 20619

$775,000
4.70 AC lot

Commercial parcel within Wildewood Technology Park near defense, aerospace, and technology organizations in St. Mary’s County.

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Automotive Property With Service Center
Automotive Property With Service Center

22380 & 22384 THREE NOTCH ROAD, Lexington Park, MD 20653

$4,490,000
14,000 sqft 4.17 AC lot

Mixed-use commercial site with an existing service center and flexible MXM zoning.

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Large Commercial Land Assemblage
Large Commercial Land Assemblage

COTTONWOOD Parkway, California, MD 20619

$16,000,000
141.46 AC lot

Commercially and industrially zoned land assemblage near Naval Air Station Patuxent River.

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Flat Commercial Land
Flat Commercial Land

SAINT JOHNS Road, Hollywood, MD 20636

$200,000
1.20 AC lot

Vacant open parcel with public water and sewer adjacent, positioned at a two-road intersection.

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Corner Commercial Land
Corner Commercial Land

26350 THREE NOTCH ROAD, Mechanicsville, MD 20659

$200,000
2.56 AC lot

Corner parcel with RCL zoning and exposure along Route 235 northbound.

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Automotive Repair Shop Property
Automotive Repair Shop Property

20098 PINEY POINT ROAD, Callaway, MD 20620

$1,100,000
5,939 sqft

Includes a commercial shop with workshop, office, storage, restrooms, and a bay door, plus ample parking.

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TMX-Zoned Commercial Corner Lot
TMX-Zoned Commercial Corner Lot

29800 THREE NOTCH Road, Charlotte Hall, MD 20622

Contact for pricing
3.30 AC lot

Cleared land with access from Route 5 and Carpenter Lane, within a Town Center Mixed Use zoning district.

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Korean-Japanese Restaurant Space
Korean-Japanese Restaurant Space

46300 LEXINGTON VILLAGE Way, Lexington Park, MD 20653

$399,000

Established dining property with a fitted kitchen, dining area, central HVAC, and shopping-center placement.

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Four-Story Office Building
Four-Story Office Building

45370 Alton Ln, California, MD 20619

$1,250,000
8,042 sqft

Four-story office building with 8 units and road frontage on Rt 235.

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Korean-Japanese Restaurant
Korean-Japanese Restaurant

46300 LEXINGTON VILLAGE Way, Lexington Park, MD 20653

$399,000

Established restaurant space with an equipped kitchen and dining area in a shopping center setting.

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Land in Mechanicsville, MD
Land in Mechanicsville, MD

28948 AUTUMNWOOD Drive, Mechanicsville, MD 20659

$65,000
1.00 AC lot

One-acre land parcel in Mechanicsville, Maryland, for sale.

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Ground-Floor Spa and Wellness Condominium
Ground-Floor Spa and Wellness Condominium

22335 EXPLORATION DRIVE #1000, Lexington Park, MD 20653

$464,900
2,784 sqft

Flexible suite includes private rooms, bathrooms, storage, and parking for salon, clinical, or office configurations.

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Cleared Commercial Land
Cleared Commercial Land

45252 HAPPYLAND Road, Valley Lee, MD 20692

$150,000
1.75 AC lot

Cleared parcel with Rural Commercial Limited zoning for localized commercial use potential.

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Ground-Floor Medical Office Condo
Ground-Floor Medical Office Condo

22335 Exploration Dr Unit 1010, Lexington Park, MD 20653

$269,900
1,574 sqft

Ground-level suite with multiple private rooms, reception area, and two bathrooms in a professional building with dedicated parking.

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Commercial Land with Existing Improvements
Commercial Land with Existing Improvements

26511 Loveville Rd, Mechanicsville, MD 20659

$799,000
3,200 sqft

The site combines open acreage, gravel circulation areas, wooded buffers, and an existing structure requiring substantial repair.

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Office Condominium with Open Layout
Office Condominium with Open Layout

22888 Three Notch Rd Unit 301, Lexington Park, MD 20653

$250,000
1,582 sqft

Flexible office condominium with natural light, elevator access, and an ADA-compliant restroom.

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Law Office with Private Rear Entrance
Law Office with Private Rear Entrance

21689 Great Mills Rd, Lexington Park, MD 20653

$499,900
2,226 sqft

Well-configured office space with private rear entry, multiple offices, and a full bath for professional or mixed-use tenants.

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Restored Horse Farm Estate with Barns
Restored Horse Farm Estate with Barns

45433 DRAYDEN ROAD, Valley Lee, MD 20692

$2,250,000
4,228 sqft

Restored 1880 manor home on 39 acres with five fenced pastures, a dressage arena, and two barns with stalls.

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Ground-Floor Medical Office Condo
Ground-Floor Medical Office Condo

1010-22335 Exploration Dr, Lexington Park, MD 20653

$269,900
1,574 sqft

Ground-level suite with reception area, multiple private offices, and two bathrooms in a professional building with dedicated parking.

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Restaurant Space with Equipped Kitchen
Restaurant Space with Equipped Kitchen

46300 Lexington Village Way, Lexington Park, MD 20653

$399,000
1,976 sqft

Established dining operation in Lexington Village Shopping Center with central air and available parking.

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Retail Space
Retail Space

29015 THREE NOTCH ROAD #8, Mechanicsville, MD 20659

Contact for pricing
13,972 sqft

Retail suite in Mechanicsville with tenant-paid electric, internet, and general upkeep.

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Office Unit with Private Restroom
Office Unit with Private Restroom

23680 THREE NOTCH ROAD #202-B, Hollywood, MD 20636

Contact for pricing
18,560 sqft

Four private offices, reception space, natural light, and on-site parking support professional office operations.

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St Mary's County, MD Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in St Mary's County, MD, showcased through 59 active listings on our real estate platform. These investment opportunities span a total of 310,354 square feet of properties for sale, with an estimated market value of $66,423,999.

Sale prices for business properties in St Mary's County, MD start at $65,000, averaging $1,581,523, and reaching up to $16,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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