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    Lee County, IA Commercial Real Estate for Sale

    31 results
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    Iconic Downtown Investment Opportunity
    $800,000
    0.39 Acres

    Iconic Downtown Investment Opportunity

    629 Blondeau St, Keokuk, IA 52632

    Multi-use commercial building with strong income and timeless character.

    • Income‑producing commercial building with 7 leased spaces and diversified revenue streams.
    • Expansive third‑floor event center featuring a restaurant‑style kitchen, bar, and ballroom.
    • Spacious 2,800 sq ft, 4‑bedroom apartment on the second floor for owner occupancy or rental income.
    • Prime downtown location with high visibility and accessibility.
    • Elevator access to all three floors.
    Updated: Jan 23
    View details
    Remodeled Commercial Building on Highway
    $210,000
    0.48 Acres

    Remodeled Commercial Building on Highway

    1219 Avenue H, Fort Madison, IA 52627

    Multi-purpose commercial building with high visibility and versatile layout.

    • High visibility location on Hwy. 61 with commercial zoning and signage.
    • Extensive remodeling since 2021 including new HVAC, water heater, electrical, plumbing, and floor coverings.
    • Versatile layout suitable for office, retail, service, or investment use with multi‑tenant income potential.
    • Two separate entrances and functional layout with office space (3 offices, reception, conference room, kitchen, bath) and retail/showroom area with warehouse/storage.
    • New roof and asphalt parking lot, freshly painted exterior.
    Updated: Feb 21
    View details
    Mixed-Use Investment Opportunity in Keokuk
    $99,000
    0.18 Acres

    Mixed-Use Investment Opportunity in Keokuk

    Mixed-use property with immediate income and upside potential.

    712 Main St, Keokuk, IA 52632
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    Fort Madison Development Opportunity
    $725,000
    49.02 Acres

    Fort Madison Development Opportunity

    49.02 acre lot for potential development in Fort Madison.

    Fort Madison, IA 52627
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    Versatile Land Opportunity in Iowa
    $385,000
    15.98 Acres

    Versatile Land Opportunity in Iowa

    Two parcels totaling 15.98 acres suitable for residential or commercial development.

    4601 Riv Bnd Sub, Fort Madison, IA 52627
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    Refurbished Gymnasium in Solid Brick Structure
    $315,000
    0.80 Acres

    Refurbished Gymnasium in Solid Brick Structure

    Adaptable commercial building with refurbished gymnasium and large classrooms.

    914 Timea St, Keokuk, IA 52632
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    Commercial Land in Fort Madison, Iowa
    $125,000
    2.62 Acres

    Commercial Land in Fort Madison, Iowa

    2.62-acre commercial land ideal for development in Fort Madison.

    4420 Avenue L, Sawyer, IA 52627
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    Commercial Land Near Keokuk Bridge
    Contact for pricing
    0.58 Acres

    Commercial Land Near Keokuk Bridge

    Visible commercial lot near Keokuk bridge, suitable for business.

    2nd Main St, Keokuk, IA 52632
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    Keokuk Land Development Opportunity
    $289,000
    14.47 Acres

    Keokuk Land Development Opportunity

    Prime land parcel with high visibility and development potential.

    Main St, Keokuk, IA 52632
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    Donnellson Farm/Estate Offered in Tracts
    $50,000
    149.00 Acres

    Donnellson Farm/Estate Offered in Tracts

    149± acre farm in 3 tracts offered online.

    2251 150Th Ave, Donnellson, IA 52625
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    Lee County Farmland Auction
    Pending
    Contact for pricing

    Lee County Farmland Auction

    345.03 acres of farmland for sale near Donnellson, Iowa.

    190th 130Th Ave, Donnellson, IA 52625
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    Lee County Farmland Auction
    Pending
    Contact for pricing

    Lee County Farmland Auction

    345.03 acres of high-quality farmland in Lee County, Iowa.

    190th 130Th Ave, Donnellson, IA 52625
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    Hunting Farm with Income Potential
    $1,050,000
    169.15 Acres

    Hunting Farm with Income Potential

    Classic southeast Iowa hunting farm with income and habitat.

    300Th St, Argyle, IA 52619
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    Iowa Hunting Farm with Income
    $1,050,000
    169.15 Acres

    Iowa Hunting Farm with Income

    Classic southeast Iowa hunting farm near Argyle with CRP income.

    300Th St, Argyle, IA 52619
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    Keokuk Land For Sale
    Contact for pricing
    0.10 Acres

    Keokuk Land For Sale

    Flat city lot in the heart of Keokuk.

    1111 Bank St, Keokuk, IA 52632
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    Lee County Farmland Opportunity
    Contact for pricing
    532.64 Acres

    Lee County Farmland Opportunity

    532.64 acres of high-quality farmland available for purchase.

    239Th Ave, Montrose, IA 52639
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    Scenic Land Near Ft. Madison
    $754,560
    104.80 Acres

    Scenic Land Near Ft. Madison

    Secluded 104.8-acre property with timber and CRP land.

    Blues Hwy & Blf Rd, Fort Madison, IA 52627
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    Keokuk Retail Investment Opportunity
    $405,000
    2,580 SF

    Keokuk Retail Investment Opportunity

    High-traffic Main Street retail building, strong tenant.

    829 Main St, Keokuk, IA 52632
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    Keokuk Retail Center Investment
    $850,000
    26,200 SF

    Keokuk Retail Center Investment

    High-yield, multi-tenant shopping center

    1220 Main St, Keokuk, IA 52632
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    Endon Center: Keokuk Retail Investment
    $850,000
    22,200 SF

    Endon Center: Keokuk Retail Investment

    High-yield shopping center, 5 tenants, 100% occupied.

    3533 Main St, Keokuk, IA 52632
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    Keokuk Hotel: Value-Add Opportunity
    $3,200,000
    52,080 SF

    Keokuk Hotel: Value-Add Opportunity

    80-Room Hotel, High-Visibility Location

    325 Main St, Keokuk, IA 52632
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    Prime Keokuk Commercial Space
    $120,000
    3,589 SF

    Prime Keokuk Commercial Space

    High-visibility Main Street location, ready for your business.

    205 Main St, Keokuk, IA 52632
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    Prime Keokuk Commercial Office Building
    $175,000
    1,600 SF

    Prime Keokuk Commercial Office Building

    Spacious office, high visibility, ample parking.

    3437 Main St, Keokuk, IA 52632
    View details
    Historic Keokuk Church & Parsonage
    $126,000
    9,328 SF

    Historic Keokuk Church & Parsonage

    Stately brick church, event space potential.

    1028 Exchange St, Keokuk, IA 52632
    View details

    Lee County, IA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 31 commercial real estate for sale in Lee County, IA, showcased through 31 active listings on our real estate platform. These investment opportunities span a total of 30,713,284 square feet of properties for sale, with an estimated market value of $11,939,560.

    Sale prices for business properties in Lee County, IA start at $50,000, averaging $568,550, and reaching up to $3,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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