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    Lee County, IA Commercial Real Estate for Sale

    14 results
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    Iconic Downtown Investment Opportunity
    $800,000
    0.39 Acres

    Iconic Downtown Investment Opportunity

    629 Blondeau St, Keokuk, IA 52632

    Multi-use commercial building with strong income and timeless character.

    • Income‑producing commercial building with 7 leased spaces and diversified revenue streams.
    • Expansive third‑floor event center featuring a restaurant‑style kitchen, bar, and ballroom.
    • Spacious 2,800 sq ft, 4‑bedroom apartment on the second floor for owner occupancy or rental income.
    • Prime downtown location with high visibility and accessibility.
    • Elevator access to all three floors.
    Updated: Nov 1, 2025
    View details
    Refurbished Gymnasium in Solid Brick Structure
    $315,000
    0.80 Acres

    Refurbished Gymnasium in Solid Brick Structure

    914 Timea St, Keokuk, IA 52632

    Adaptable commercial building with refurbished gymnasium and large classrooms.

    • Refurbished gymnasium serves as a central feature.
    • Over 26,000 square feet under roof.
    • Large 77,000 sq ft lot with an extra parcel.
    • 14 large classrooms and 6+ offices.
    • Solid brick construction.
    Updated: Oct 8, 2025
    View details
    Keokuk Retail Investment Opportunity
    $405,000
    2,580 SF

    Keokuk Retail Investment Opportunity

    High-traffic Main Street retail building, strong tenant.

    829 Main St, Keokuk, IA 52632
    View details
    Historic Keokuk Church & Parsonage
    $126,000
    9,328 SF

    Historic Keokuk Church & Parsonage

    Stately brick church, event space potential.

    1028 Exchange St, Keokuk, IA 52632
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    Historic Main Street Commercial
    $125,000

    Historic Main Street Commercial

    Prime Keokuk location, 3840 sq ft.

    429 Main St, Keokuk, IA 52632
    View details
    Keokuk Mixed-Use Commercial Building
    $125,000
    5,967 SF

    Keokuk Mixed-Use Commercial Building

    Prime location, multiple income streams.

    22 5Th St, Keokuk, IA 52632
    View details
    Prime Keokuk Commercial Space
    $120,000
    3,589 SF

    Prime Keokuk Commercial Space

    High-visibility Main Street location, ready for your business.

    205 Main St, Keokuk, IA 52632
    View details
    Donnellson Commercial Building - Huge Potential
    $82,000
    0.16 Acres

    Donnellson Commercial Building - Huge Potential

    Versatile three-level building with kitchen & garage.

    600 Main St, Donnellson, IA 52625
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    Keokuk Hotel: Value-Add Opportunity
    $3,200,000
    52,080 SF

    Keokuk Hotel: Value-Add Opportunity

    80-Room Hotel, High-Visibility Location

    325 Main St, Keokuk, IA 52632
    View details
    Keokuk Mixed-Use Building - $7,000
    Contact for pricing

    Keokuk Mixed-Use Building - $7,000

    Renovation Opportunity: Bar Included, As-Is.

    1318 Main St, Keokuk, IA 52632
    View details
    Keokuk Multi-Family Income Property
    $179,000
    0.14 Acres

    Keokuk Multi-Family Income Property

    Four-unit building, great rental income.

    624 Palean St, Keokuk, IA 52632
    View details
    Prime Keokuk Commercial Office Building
    $175,000
    1,600 SF

    Prime Keokuk Commercial Office Building

    Spacious office, high visibility, ample parking.

    3437 Main St, Keokuk, IA 52632
    View details
    Keokuk Retail Center Investment
    $850,000
    26,200 SF

    Keokuk Retail Center Investment

    High-yield, multi-tenant shopping center

    1220 Main St, Keokuk, IA 52632
    View details
    Endon Center: Keokuk Retail Investment
    $850,000
    22,200 SF

    Endon Center: Keokuk Retail Investment

    High-yield shopping center, 5 tenants, 100% occupied.

    3533 Main St, Keokuk, IA 52632
    View details
    Based on your search, we've compiled 2227 Potential Opportunities for your consideration. Besides 14 Active listings in Lee County, IA, we suggest exploring several alternatives: similar 2212 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Keokuk Land For Sale
    Contact for pricing
    0.10 Acres

    Keokuk Land For Sale

    Flat city lot in the heart of Keokuk.

    1111 Bank St, Keokuk, IA 52632
    View details

    Explore Off-Market Properties in Lee County, IA

    Consider similar Off-Market properties in Lee County, IA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    613 Avenue G

    613 Avenue G

    Office Properties & Spaces
    Value Estimation by Request
    613 Avenue G, Fort Madison, IA 52627
    View details
    205 Main St

    205 Main St

    Restaurants • 3,589 SF
    Value Estimation by Request
    205 Main St, Montrose, IA 52632
    View details
    624 Palean St

    624 Palean St

    Commercial real estate • 0.14 Acres
    Value Estimation by Request
    624 Palean St, Keokuk, IA 52632
    View details
    1028 Exchange St

    1028 Exchange St

    Commercial real estate • 9,328 SF
    Value Estimation by Request
    1028 Exchange St, Keokuk, IA 52632
    View details
    2721 340Th St

    2721 340Th St

    Multifamily properties
    Value Estimation by Request
    2721 340Th St, Keokuk, IA 52632
    View details
    325 Main St

    325 Main St

    Commercial real estate • 52,080 SF
    Value Estimation by Request
    325 Main St, Keokuk, IA 52632
    View details
    3503 243rd Ave

    3503 243rd Ave

    WAREHOUSE, STORAGE • 960 SF
    Value Estimation
    $65,000
    3503 243rd Ave, Keokuk, IA 52632-9601
    View details
    Houghton, IA 52631

    Houghton, IA 52631

    WAREHOUSE, STORAGE • 1,856 SF
    Value Estimation by Request
    Houghton, IA 52631
    View details
    Keokuk, IA 52632

    Keokuk, IA 52632

    LIGHT INDUSTRIAL • 5,610 SF
    Value Estimation
    $140,000
    Keokuk, IA 52632
    View details
    3503 243rd Ave

    3503 243rd Ave

    MANUFACTURING (LIGHT) • 3,250 SF
    Value Estimation
    $205,000
    3503 243rd Ave, Keokuk, IA 52632-9601
    View details

    Lee County, IA Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1625 commercial real estate investment opportunities in Lee County, IA with 14 listings featured on our commercial real estate marketplace. The current inventory includes 128,068,475 square feet of properties with an estimated value of $244,204,960.

    Estimated prices for commercial real estate in Lee County, IA begin at $42,500, with an average of $311,883 and extend to $3,315,000.

    In Lee County, IA, current investment values show:

    • Industrial properties positioned at $351,495
    • Retail properties measuring $286,607
    • Individual retail properties assessed at $274,464
    • Other warehouses calculated at $377,204
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