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    Mississippi County, AR Commercial Real Estate for Sale

    43 results
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    Osceola Commercial Building and Land
    $800,000
    6,000 SF

    Osceola Commercial Building and Land

    2965 W Keiser Avenue, Osceola, AR 72370

    Commercial building with highway frontage in the heart of Osceola.

    • 6,000 sq ft commercial building on +/-1 acre in Osceola city limits.
    • Highway frontage on W Keiser, the main thoroughfare into the city.
    • New construction (built in 2023) with New Traditional architectural style.
    • Equipped with overhead doors and loading dock.
    • Features public restrooms, smoke detector, and burglar alarm.
    Updated: Mar 13
    View details
    Manila, AR Industrial Opportunity
    $325,900
    6,092 SF

    Manila, AR Industrial Opportunity

    2695 W State Highway 18, Manila, AR 72442

    6092 SF property suitable for business or duck lodge.

    • 6092 sq ft property suitable for business, lodge, or venue.
    • Minutes from Big Lake Wildlife area, ideal for a duck lodge.
    • Heated and cooled spacious office with lobby, kitchen, and 2 restrooms.
    • Insulated and heated shop area with 2 roll‑up doors and 14ft wall height.
    • Fenced area with drive‑through gates.
    Updated: Oct 16, 2025
    View details
    Blytheville Office Building For Sale
    $385,000
    5,200 SF

    Blytheville Office Building For Sale

    Office building with 5,200 square feet of space.

    102 WALNUT, Blytheville, AR 72315
    View details
    Blytheville Office Building For Sale
    $385,000
    5,200 SF

    Blytheville Office Building For Sale

    Office building with 5,200 square feet of space.

    102 WALNUT, Blytheville, AR 72315
    View details
    Gosnell Commercial Property on Highway
    $285,000
    2,976 SF

    Gosnell Commercial Property on Highway

    Commercial property with warehouse, office, and living area.

    1108 HIGHWAY 181, Gosnell, AR 72315
    View details
    Renovated Commercial Property in Osceola
    $195,000
    1,600 SF

    Renovated Commercial Property in Osceola

    Versatile commercial space suitable for office, retail, or restaurant.

    107/109 E HALE AVENUE, Osceola, AR 72370
    View details
    Osceola Retail Opportunity
    $370,000
    1,890 SF

    Osceola Retail Opportunity

    Retail space available for purchase in Osceola, Arkansas.

    1315 W KEISER AVENUE, Osceola, AR 72370
    View details
    Large Retail Opportunity in Blytheville
    $1,056,000
    56,365 SF

    Large Retail Opportunity in Blytheville

    Large commercial property on 6.19 acres, ideal for redevelopment.

    1040 E Main Street, Blytheville, AR 72315
    View details
    Osceola Office Space Opportunity
    $150,000
    2,014 SF

    Osceola Office Space Opportunity

    2014 SF office space centrally located in Osceola, Arkansas.

    515 W LEE AVENUE, Osceola, AR 72370
    View details
    Osceola Commercial Land For Sale
    $500,000
    3.48 Acres

    Osceola Commercial Land For Sale

    Highly visible 3.48-acre commercial lot near I-55 interchange.

    State Hwy 140, Osceola, AR 72370
    View details
    Highway Frontage Investment Opportunity
    $399,900
    624 SF

    Highway Frontage Investment Opportunity

    Multi-parcel commercial investment with income-producing potential in Manila, Arkansas.

    2655 W State Highway 18, Manila, AR 72442
    View details
    Blytheville Commercial Opportunity on Main
    $1,056,000
    56,365 SF

    Blytheville Commercial Opportunity on Main

    Large commercial building and land for redevelopment or flagship operation.

    1040 E Main Street, Blytheville, AR 72315
    View details
    Spacious Warehouse in Blytheville, AR
    $795,000
    40,000 SF

    Spacious Warehouse in Blytheville, AR

    40,000 sq ft warehouse ideal for distribution, manufacturing, storage.

    0 ELM & WILSON, Blytheville, AR 72315
    View details
    Commercial Business & Residential Opportunity
    $275,000
    1,440 SF

    Commercial Business & Residential Opportunity

    Commercial building, tire shop, residential property on 2.92 acres.

    3315 DIVISION STREET, Blytheville, AR 72315
    View details
    Commercial Land on Air Base
    $285,000
    3.42 Acres

    Commercial Land on Air Base

    3.42 acres with warehouse/office space for business.

    1108 HIGHWAY 181, Gosnell, AR 72315
    View details
    Blytheville Commercial Building with Fenced Yard
    $175,000
    2,545 SF

    Blytheville Commercial Building with Fenced Yard

    2545 SF commercial building with fenced yard and paved parking.

    206 DAVIS STREET, Blytheville, AR 72315
    View details
    Blytheville Commercial Building on Corner
    $89,000
    2,000 SF

    Blytheville Commercial Building on Corner

    Versatile 2,000 SF building suitable for various purposes.

    2101 W ROSE STREET, Blytheville, AR 72315
    View details
    Warehouse in Blytheville, Arkansas
    $135,000
    10,547 SF

    Warehouse in Blytheville, Arkansas

    Warehouse property available for sale in Blytheville, Arkansas.

    223 N 1st St, Blytheville, AR 72315
    View details
    Blytheville Warehouse and Industrial Property
    $1,500,000
    58,766 SF

    Blytheville Warehouse and Industrial Property

    Warehouse and industrial property available for sale in Blytheville, AR.

    956 E MAIN STREET, Blytheville, AR 72315
    View details
    Blytheville Farm Land Available
    $300,000
    60.00 Acres

    Blytheville Farm Land Available

    60 acre farm south of Blytheville, Arkansas for sale.

    none S ACRES, Blytheville, AR
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    Osceola Land Ideal for Development
    Contact for pricing
    591.25 Acres

    Osceola Land Ideal for Development

    Prime location near I-55, suitable for solar farm/data center.

    1169 S HWY 119, Osceola, AR 72370
    View details
    Large Commercial Structure on Main
    $1,056,000
    56,365 SF

    Large Commercial Structure on Main

    Expansive commercial structure on 6.19 acres in Blytheville.

    1040 E Main Street, Blytheville, AR 72315
    View details
    Mississippi River Recreational Farm
    $1,950,000
    1,004.52 Acres

    Mississippi River Recreational Farm

    1004.52 acre recreational farm with game-rich timber.

    TBD County Road 394, Luxora, AR 72358
    View details
    14.77 Acres Fronting I-55
    Contact for pricing

    14.77 Acres Fronting I-55

    14.77 acres of commercial land fronting I-55 for sale.

    830 N Service Rd, Blytheville, AR 72315
    View details

    Mississippi County, AR Commercial Real Estate Investment Opportunities Market Analysis

    Explore 43 commercial real estate for sale in Mississippi County, AR, showcased through 43 active listings on our real estate platform. These investment opportunities span a total of 76,428,199 square feet of properties for sale, with an estimated market value of $65,843,700.

    Sale prices for business properties in Mississippi County, AR start at $125,000, averaging $2,992,895, and reaching up to $55,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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