Grayson County, VA Commercial real estate for Rent & Lease

Updated: Jun 24

Guynn Shopping Center Retail Space

568 - 588 East Main Street, Independence, VA 24348

$10 SF/Yr

Retail or office use supported
568–588 East Main Street, Independence, VA 24348
Ample parking for tenants and customers
East Main Street visibility and accessibility
Reported foot traffic at the shopping center

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Updated: Apr 23, 2025

Retail Space on East Main

568-588 E Main St, Independence, VA

Contact for pricing

760 sqft 9.92 AC lot

Prime location on East Main Street with high visibility
Excellent foot traffic for maximum exposure
Ample parking for tenants and customers
Versatile space suitable for various business types

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Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 2 Active listings in Grayson County, VA, we suggest exploring alternatives. Similar 22 Properties for Sales.

Similar Spaces for Sale in Grayson County, VA

Consider Similar Space for Sale. We found 22 Spaces matching your search parameters.

Manufacturing Building with Loading Docks

812 E Main Street, Fries, VA 24330

$199,900

4,032 sqft

A two-level commercial property offers shop space below and an upper floor with potential for office or residential conversion, subject to approvals.

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Medical Office Building with Exam Rooms

139 E Main, Independence, VA 24348

$350,000

5,100 sqft 0.24 AC lot

Main Street property with an established clinical layout, public utilities, and ongoing occupancy.

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Wedding and Event Venue Property

639 Wagon Wheel Rd, Elk Creek, VA 24326

$1,575,000

2,160 sqft

Turnkey event center with a finished guest home and a 4,224 sq ft event barn with ADA-compliant restrooms.

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Riverside Storefront with Flexible Layout

12 Scenic Rd, Fries, VA 24330

$199,900

910 sqft

Zoned RF with vested commercial rights, the property sits across from a New River boat ramp.

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Historic Live-Work Building

116 W Main St., Independence, VA 24348

$499,900

4,450 sqft

Renovated mixed-use property combines an upper-level residence with two main-level retail units in downtown Independence.

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Commercial Land with Garage Buildings

10714 Troutdale Highway, Troutdale, VA 24378

$359,900

3.84 AC lot

Open commercial acreage includes garage buildings, multiple access points, public water, and frontage on two state-maintained roads.

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Updated Flex Space with Two Entrances

1039 N Independence Ave., Independence, VA 24348

$139,900

1,222 sqft

Recently upgraded commercial space with public restrooms, municipal utilities, and separate electric meters.

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Agricultural Land with Mountain Views

TBD 75A Low Gap, Troutdale, VA 24378

$468,750

75.00 AC lot

A mix of open ground and mature woodland is served by existing farm roads and offers several ridge-top building locations.

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Agricultural Land with Creek

TBD 66A Low Gap, Troutdale, VA 24378

$414,000

66.25 AC lot

A mix of meadow and timber includes an established farm road and an open knoll near the property’s upper elevation.

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Unrestricted Farmland with Well and Septic

Edwards Chapel Rd, Fries, VA 24330

$244,900

23.19 AC lot

Unrestricted Ag-zoned farmland with a level building site, well and septic tank, plus electricity available.

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Agricultural Land with Well and Septic

545 Old Fries Junction, Fries, VA 24330

$194,900

19.56 AC lot

Level building site with an existing well, septic system, and available electricity.

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Commercial Land with Road Frontage

Scenic Road, Fries, VA 24330

$75,000

1.31 AC lot

The cleared parcel includes paved parking, with commercial use subject to zoning approval.

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Three-Lot Commercial Land

121 S Independence Ave, Independence, VA 24348

$199,000

0.80 AC lot

Commercial zoning with public water, public sewer, and electricity available.

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21+ Acre Land Tract

3323 Rugby Road, Mouth Of Wilson, VA 24363

$159,900

21.07 AC lot

Land near Grayson Highlands, suitable for horses or cattle.

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Historic Bed & Breakfast

509 W Main St, Independence, VA 24348

$650,000

Guest rooms have private bathrooms, with shared gathering space and a large kitchen on the main level.

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Commercial Land with Garage Buildings

10714 Troutdale Highway, Troutdale, VA 24378

$359,900

Cleared commercial land with two garage buildings, multiple access points, and power connections.

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Mountain Recreational Acreage with Creek

460 Grubbs Chapel Ln, Independence, VA 24348

$425,000

60.64 AC lot

60.64-acre tract in Grayson County with creek, well and spring, long road frontage, and pasture with timber.

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Fenced Agricultural Land

Fox Creek Rd lot: 0, Mouth Of Wilson, VA 24363

$69,000

5.40 AC lot

Fenced pastureland with AG zoning, mountain views, and convenient road access.

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Historic Bed and Breakfast

509 West Main Street, Fries, VA 24330

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Eleven guest rooms each have a private bathroom, and furnishings and equipment convey with the property.

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Historic Specialty Property

81 Timberline Rd, Troutdale, VA 24378

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Residential zoning, prior commercial use, and existing well and septic service define the property's current setup.

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Manufacturing Property with 200-Amp Service

81 Timberline Drive lot: 29A-A-99A Pt, Troutdale, VA 24378

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0.78 AC lot

Existing building with well, septic, spring water, and electricity available.

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Prime Commercial Land Opportunity

121 South Independence Ave, Independence, VA 24348

$199,000

0.80 AC lot

Three lots ideal for franchise or new business construction.

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