Downtown Houston, TX Commercial Real Estate for Lease

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Prime Midtown Retail Space Available
Updated: Nov 21, 2025
Prime Midtown Retail Space Available

510 Gray Street, Houston, TX 77002

$32 SF/Yr
14,788 sqft
Highly coveted location in Midtown.
Located at the SE corner of Gray Street and Brazos Street.
In an established, infill area of the city.
Conveniently located near Interstate 45.
Conveniently located near Highway 59.
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TX, Houston - 1415 Louisiana St
Updated: Feb 19
TX, Houston - 1415 Louisiana St

1415 Louisiana St, Houston, TX 77002

$129-$16,073/Mo
16 spaces available 11-1,958 sqft
Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
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TX, Houston - 708 Main Street
TX, Houston - 708 Main Street

708 Main St, Houston, TX 77002

$129-$12,607/Mo
15 spaces available 11-2,061 sqft

Find fully flexible work and meeting space in TX, Houston - 708 Main Street. Book a tour & get info

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Downtown Office Tower for Lease
Downtown Office Tower for Lease

700 Louisiana Street, Houston, TX 77002

$27.50 SF/Yr
370,756 sqft

56-story office tower with retail space in downtown Houston.

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Houston Office Space For Rent
Houston Office Space For Rent

1000 Louisiana Street, Houston, TX 77002

$28 SF/Yr
580,242 sqft

71-story office building in downtown Houston with 1.7M+ sqft.

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Historic Houston Building Retail Space
Historic Houston Building Retail Space

15 N Chenevert Street, Suite 100, Houston, TX 77002

$4,500/Mo
2,400 sqft

Loft-style retail space in a historic Houston building.

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Downtown Houston Office Space Available
Downtown Houston Office Space Available

1001 McKinney Street, Houston, TX 77002

$19 SF/Yr
116,163 sqft

Class-A office building with tenant-focused services and amenities.

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Downtown Houston Office Space
Downtown Houston Office Space

1010 Travis Street, Houston, TX 77002

$19.50 SF/Yr
28,747 sqft

Office space available for lease in downtown Houston.

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Office Space in Houston Center
Office Space in Houston Center

1222 Rusk St, Houston, TX 77002

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1 sqft

Office space available for lease in Houston, Texas.

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Downtown Houston Office Space
Downtown Houston Office Space

711 Louisiana St, Houston, TX 77002

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1,443 sqft

Office space available for rent in downtown Houston.

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Retail Space Available For Lease
Retail Space Available For Lease

1070 Dallas St, Houston, TX 77002

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2,037 sqft

Retail space available for lease in Houston, Texas.

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Houston Office Space for Lease
Houston Office Space for Lease

500 Dallas Street, Houston, TX 77002

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344,141 sqft

Office space in Houston's Allen Center with many amenities.

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Downtown Office Space with Amenities
Downtown Office Space with Amenities

1001 Louisiana Street, Houston, TX 77002

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124,772 sqft

Office space with conferencing center and tunnel access to amenities.

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Downtown Office Building with Tunnel Access
Downtown Office Building with Tunnel Access

919 Milam Street, Houston, TX 77002

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382,969 sqft

Centrally located office building with downtown tunnel system access.

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Downtown Boutique Office Destination
Downtown Boutique Office Destination

801 Louisiana Street, Houston, TX 77002

$16.50 SF/Yr
12,457 sqft

Boutique office space in Houston's Central Business District.

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Office Space For Rent
Office Space For Rent

333 Clay Street, #2100, Houston, TX 77002

$15 SF/Yr

Office space available for lease in Houston, Texas.

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Downtown Office Space Available
Downtown Office Space Available

811 Louisiana Street, Houston, TX 77002

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19,222 sqft

LEED-EB Gold Certified office building with amenities and tunnel access.

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Retail and Restaurant Spaces Available
Retail and Restaurant Spaces Available

308 W Gray St, Houston, TX 77002

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1,600 sqft

Retail and restaurant spaces in Houston's Midtown submarket.

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Houston Office Space for Rent
Houston Office Space for Rent

1200 Smith Street, Houston, TX 77002

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447,313 sqft

Office space in a central Houston location with many amenities.

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Bank of America Tower Office
Bank of America Tower Office

800 Capitol Street, Houston, TX 77002

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780,000 sqft

Located in Houston's fastest growing city, close to museums.

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Office Building in Houston, TX
Office Building in Houston, TX

712 Main Street, Houston, TX 77002

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122,367 sqft

Office building with 122,367 square feet available for rent.

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Downtown Houston Specialty Property
Downtown Houston Specialty Property

208 Travis, Houston, TX 77002

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1,250 sqft

Specialty property available for rent in downtown Houston.

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Flexible Office Coworking Space
Flexible Office Coworking Space

1415 Louisiana St Houston, Houston, TX 77002

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Flexible private offices, meeting rooms, and coworking with business-grade WiFi and onsite amenities at 1415 Louisiana St.

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Coworking Office Suite
Coworking Office Suite

1201 Fannin Street, Suite 100, Houston, TX 77002

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Flexible creative workspace with meeting rooms, open lounges, and unlimited Wi-Fi within a mixed-use downtown setting.

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Downtown Houston, TX Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Downtown Houston, TX with 46 listings featured on our commercial real estate exchange. The current inventory includes 10,844,976 square feet of properties with an estimated lease value of $5,060,015.

Estimated lease rates for Commercial real estate in Downtown Houston, TX begin at $1.00 SF/Yr, with an average of $11,552 /Mo and extend to $2,550,000.
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