Plymouth, PA Commercial real estate for Rent & Lease

Updated: Oct 10, 2025

Class A Office Space Available

450 Plymouth Rd/Germantown Pik, Plymouth, PA

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5,648 sqft

Convenient location to major highways, public transportation, Plymouth Meeting Mall, shops, and restaurants.
Class A office space.
Fitness Center in the building.
State of the art energy management system.
Two story atrium lobby with stone, steel and wood finishes.

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Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 1 Active listings in Plymouth, PA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Three-Story Industrial Flex Building

373 High Blvd, Wilkes Barre, PA 18702

$9,814/Mo

33,000 sqft

Freight elevator-served industrial space includes loading docks, overhead doors, office buildout, and fenced truck staging.

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Professional Office Suite with Parking

41 Oxford St, Hanover Township, PA 18706

$3,000/Mo

Office suite with reception, private offices, and an open work area plus ample off-street parking.

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Three-Story Industrial Facility

Wilkes Barre, PA 18702

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33,650 sqft

Industrial building with three full stories plus basement, freight elevator, varied clear heights, and built-in office space.

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Warehouse and Light Manufacturing Facility

485 Stewart Rd, Hanover Township, PA 18706

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60,000 sqft

Well maintained warehouse sized for distribution or light manufacturing with strategic access near I-81 and Route 29.

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Similar Spaces for Sale in Plymouth, PA

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Four-Unit Residential and Retail Building

163-167 Willow Street, Plymouth, PA 18651

$229,000

4,517 sqft 2.05 AC lot

Four-unit property includes three 3-bedroom residences and one prior corner market space.

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Turnkey Bar and Club Property

1477 W Main Street, Plymouth, PA 18651

$625,000

3,200 sqft

Well-maintained bar and club offering on-site parking for about 40 vehicles and includes liquor license with adult entertainment.

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Renovated Bank Office Building

117 W Main Street, Plymouth, PA 18651

$579,000

9,543 sqft

Renovated three-story building offers zoned HVAC, three-phase electric, and parking for 28 cars.

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Remodeled Mixed-Use Triplex

159 E Main Street, Plymouth, PA 18651

$369,900

4,568 sqft

Remodeled 3-unit building with two apartments, a storefront, and a large garage plus rear parking.

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Live-Work Space with B3 Zoning

318 W Main Street, Plymouth, PA 18651

$295,000

2,142 sqft 0.15 AC lot

Renovated live-work property with a commercial-capable first floor in B-3 zoning and updated interiors.

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Remodeled Restaurant Space with Parking

215 E Main St, Plymouth, PA 18651

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1,660 sqft

Newly remodeled restaurant space available for sale with parking.

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Turn-Key To-Go Restaurant

227 E Main Street, Plymouth, PA 18651

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Restaurant includes pizza ovens and full kitchen equipment plus three bathrooms, with a rear apartment for added rental income.

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Plymouth, PA Commercial Real Estate for Lease

450 Plymouth Rd/Germantown Pik, Plymouth, PA