Plymouth, PA Commercial real estate for Rent & Lease

Updated: Oct 10, 2025

Class A Office Space Available

450 Plymouth Rd/Germantown Pik, Plymouth, PA

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5,648 sqft 5.18 AC lot

Convenient location to major highways, public transportation, Plymouth Meeting Mall, shops, and restaurants.
Class A office space.
Fitness Center in the building.
State of the art energy management system.
Two story atrium lobby with stone, steel and wood finishes.

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Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 1 Active listings in Plymouth, PA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Three-Story Industrial Flex Building

373 High Blvd, Wilkes Barre, PA 18702

$9,814/Mo

33,000 sqft

Freight elevator-served industrial space includes loading docks, overhead doors, office buildout, and fenced truck staging.

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Professional Office Suite with Parking

41 Oxford St, Hanover Township, PA 18706

$3,000/Mo

Office suite with reception, private offices, and an open work area plus ample off-street parking.

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Warehouse and Light Manufacturing Facility

485 Stewart Rd, Hanover Township, PA 18706

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60,000 sqft

Well maintained warehouse sized for distribution or light manufacturing with strategic access near I-81 and Route 29.

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Versatile Strip Center For Lease

Wilkes Barre, PA 18706

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10,000 SF strip center in a high-traffic commercial area.

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Similar Spaces for Sale in Plymouth, PA

Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

Four-Unit Quadplex with Parking

163-167 Willow Street, Plymouth, PA 18651

$229,000

4,517 sqft 2.05 AC lot

B2-zoned property combines residential units with a former commercial space.

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Renovated Three-Story Office Building

117 W Main Street, Plymouth, PA 18651

$579,000

9,543 sqft

Commercial zoning with finished space suited to office or commercial use.

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Remodeled Three-Unit Mixed-Use Building

159 E Main Street, Plymouth, PA 18651

$349,900

4,568 sqft

The property combines two apartments, a storefront, garage space, and rear parking within a Commercial-zoned building.

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Four-Unit Multifamily with Parking

163-167 Willow St, Plymouth, PA 18651

$229,000

4,517 sqft

Three residential units offer three bedrooms each, alongside a former corner-market unit and off-site parking across the street.

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Flex Space with Garage

573 E Main Street, Plymouth, PA 18651

$290,000

2,625 sqft

Adaptable commercial space offers a practical layout for workshop, storage, or business operations.

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Renovated Three-Story Office Building

117 W Main St, Plymouth, PA 18651

$579,000

9,543 sqft

Flexible commercial property with finished office areas, restaurant-use potential, and parking serving multiple business configurations.

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Remodeled Restaurant Space with Parking

215 E Main St, Plymouth, PA 18651

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1,660 sqft

Newly remodeled restaurant space available for sale with parking.

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Mixed-Use Building with Apartments

1 E Main St, Plymouth, PA 18651

$719,900

Two-level property combines leased residential units with first-floor commercial space, including one currently available suite.

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Plymouth, PA Commercial Real Estate for Lease

450 Plymouth Rd/Germantown Pik, Plymouth, PA