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East Syracuse, NY Commercial Real Estate for Lease

32 results
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East Syracuse Commercial Space Available
$1,900 / Mo
14,506 SF

East Syracuse Commercial Space Available

5710 Commons Park, East Syracuse, NY 13057

Class A office space in desirable East Syracuse location.

  • Highly desirable location near Widewaters Parkway with easy access to major highways and downtown Syracuse.
  • Gross lease: Landlord pays for heat, air conditioning, and electricity.
  • Impeccably maintained Class A professional building with newly remodeled kitchen and recently painted exterior.
  • Excellent accessibility: One‑story building with no stairs and plenty of free parking.
  • Access to shared restrooms, conference room, and outdoor patio.
Updated: Dec 30, 2025
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Brittonfield Parkway Medical Office
$23 SF/Yr
89,000 SF

Brittonfield Parkway Medical Office

4939 Brittonfield Pkwy, East Syracuse, NY 13057

Class A Medical Office Suites Available

  • 89,000 SF Class A medical office building in Brittonfield Office Park, conveniently located near I‑481. Anchored by CNY Family Care.
  • Excellent access and ample parking for patients throughout Central New York.
  • Brittonfield Office Park includes numerous medical tenants, including Hematology Oncology of CNY, CNY Internists, SJH Cardiology, and St. Joseph’s Physical Therapy.
Updated: Dec 11, 2024
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Divisible Office Building with Garage
Contact for pricing
2,870 SF

Divisible Office Building with Garage

16,500 SF office building divisible into 2,000+ SF suites.

1 Adler Dr, E Syracuse, NY 13057
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Collamer Office Building Space Available
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1,175 SF

Collamer Office Building Space Available

Office spaces for rent in a well-maintained building.

6670 Old Collamer Rd, E Syracuse, NY 13057
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Furnished Office Space Available
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1,895 SF

Furnished Office Space Available

Move-in ready office space with flexible lease terms.

5000 Campuswood Dr, East Syracuse, NY 13057
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Warehouse with Fenced Outdoor Storage
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5,500 SF

Warehouse with Fenced Outdoor Storage

Warehouse space available January 2026 with ample outdoor storage.

6159 E Molloy Rd, East Syracuse, NY 13057
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Class B Office Building
Contact for pricing
1,660 SF

Class B Office Building

12,000 SF office building near Interstate 481.

6315 Fly Rd, E Syracuse, NY 13057
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New Warehouse Construction Opportunity
$14 SF/Yr
30,000 SF

New Warehouse Construction Opportunity

Proposed warehouse construction with exterior storage in East Syracuse, NY.

6808 Crossbow Dr, East Syracuse, NY 13057
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East Syracuse Office Building For Rent
$4,220 / Mo
5,064 SF

East Syracuse Office Building For Rent

5,064 SF office building with yard and generator.

6331 E Molloy Rd, East Syracuse, NY 13057
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New Warehouse Construction Opportunity
$14 SF/Yr
20,000 SF

New Warehouse Construction Opportunity

Proposed warehouse construction with exterior storage in East Syracuse, NY.

6822 Crossbow Dr, East Syracuse, NY 13057
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Office Space with Private Entry
$18 SF/Yr
32,406 SF

Office Space with Private Entry

Ground floor office suite with private entry and ample windows.

6007 Fair Lakes Rd, East Syracuse, NY 13057
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Industrial/Flex Building with Heavy Power
$9 SF/Yr
17,309 SF

Industrial/Flex Building with Heavy Power

Industrial/flex building featuring heavy power and floors, additional acreage available.

6615 Towpath Rd, East Syracuse, NY 13057
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New Development Opportunity in Syracuse
Contact for pricing
26,000 SF

New Development Opportunity in Syracuse

New Class A medical/office or office/warehouse facility for lease.

6731 Fly Rd, East Syracuse, NY 13057
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Office/Warehouse Corner Space Available
Contact for pricing
1,770 SF

Office/Warehouse Corner Space Available

1,770 SF corner space for lease in East Syracuse.

6838 Ellicott Dr, East Syracuse, NY 13057
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Two-Story Office Building For Rent
Contact for pricing
675 SF

Two-Story Office Building For Rent

Two-story office building with suites ranging from 440-4,650 square feet.

6320 Fly Rd, E Syracuse, NY 13057
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Turn Key Flex Space
$10 SF/Yr
4,000 SF

Turn Key Flex Space

4,000 SF flex space with warehouse and offices.

6600 Joy Rd, East Syracuse, NY 13057
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Office Suite in Dewitt
$10 SF/Yr

Office Suite in Dewitt

Office suite in flex building at corner of Northern Blvd.

6780 Northern Blvd, East Syracuse, NY 13057
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Office with Warehouse & Storage
Contact for pricing
2,640 SF

Office with Warehouse & Storage

2,640 SF office and storage space available for lease.

5 Adler Dr, E Syracuse, NY 13057
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Retail Space with High Traffic
Contact for pricing
1,300 SF

Retail Space with High Traffic

Retail space with excellent location and accessibility.

7025 Manlius Center Rd, E Syracuse, NY 13057
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Flex Building Near Interstate 481
Contact for pricing
3,330 SF

Flex Building Near Interstate 481

25,000 SF flex building suitable for various business types.

6731 Collamer Rd, E Syracuse, NY 13057
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Renovated Warehouse Near Major Highways
$6 SF/Yr
11,560 SF

Renovated Warehouse Near Major Highways

Renovated warehouse with ample parking and highway access.

6 Adler Dr, East Syracuse, NY 13057
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E Syracuse Office Space Available
Contact for pricing
1,500 SF

E Syracuse Office Space Available

25,000 SF building with diverse tenant mix.

101 Adler Dr, E Syracuse, NY 13057
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High-Bay Warehouse and Tech Space
Contact for pricing
269,500 SF

High-Bay Warehouse and Tech Space

New high-tech/warehousing building with high-bay ceiling clearance and optional rail.

6457 Fly Rd, East Syracuse, NY 13057
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Office/Medical Building, Spring 2025
Contact for pricing
7,000 SF

Office/Medical Building, Spring 2025

7,000 SF office/medical building to be constructed Spring 2025.

820 Franklin Park Dr, East Syracuse, NY 13057
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East Syracuse, NY Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in East Syracuse, NY with 52 listings featured on our commercial real estate exchange. The current inventory includes 12,763,559,160 square feet of properties with an estimated lease value of $92,746.

Estimated lease rates for Commercial Real Estate in East Syracuse, NY begin at $1.57 SF/Yr, with an average of $7,134 /Mo and extend to $92,600.

In East Syracuse, NY, current lease rates show:

  • Office Properties & Spaces positioned at $13
  • Industrial properties measuring $10
  • Office space assessed at $11
  • Flex space calculated at $9
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