Strafford County, NH Commercial real estate for Rent & Lease

Portsmouth

170 Commerce Way, Unit 200, Portsmouth, NH 03801

$129-$25,803/Mo

11 sqft

(972) 764-8885

Flexible workspace in Portsmouth. Book a tour & get info

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Updated: Jun 30

Ground-Level Retail Office with Warehouse Option

15 Fourth Street #Floor 1, Dover, NH 3820

$19 SF/Yr

11,246 sqft · $17,806/Mo

2,600 +/- SF ground‑level retail/office space in downtown Dover, NH
Optional adjoining 8,646 +/- SF warehouse/storage space is available
Three lease scenarios: 2,600 +/- SF retail @ $18.50 PSF/MG; 8,646 +/- SF warehouse @ $9.50 PSF/MG; or combined 11,246 +/- SF @ $11.60 PSF/MG
Available June 1, 2026

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Updated: Jul 4

Downtown Restaurant Space

21 3rd St 201, Dover, NH 3820

$25 SF/Yr

4,300 sqft · $8,958/Mo

4,300± SF restaurant space
Year built 2019
Flexible layout suited for a variety of food and beverage concepts
Offered vacant; photos show prior tenant’s furniture and decor
Walk Score 72 (very walkable) and Bike Score 57 (bikeable)

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Retail/Office Space Near UNH

71 Calef Hwy, Lee, NH 3861

$18 SF/Yr

3,000 sqft · $4,500/Mo

Turnkey retail or office space in Lee, NH.

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Second-Floor Office Suite

96 Penhallow Street, Portsmouth, NH 3801

$3,700/Mo

1,300 sqft · $34 SF/Yr

Historic downtown office suite with private restroom and shared patio access, available immediately.

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Second-Floor Office Suite

96-98 Penhallow St, Portsmouth, NH 3801

$3,700/Mo

1,300 sqft · $34 SF/Yr

Historic downtown office with a private restroom, shared patio access, and exterior signage rights.

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Downtown Portsmouth Office Suites Available

501 Islington St Suite 3, Portsmouth, NH 3801

$15 SF/Yr

8,644 sqft · $10,805/Mo

Office suites for lease in downtown Portsmouth, NH.

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Mixed-Use Space Overlooking Cochecho River

31 River St Suite 102, Dover, NH 3820

$32 SF/Yr

3,294 sqft · $8,784/Mo

3,294 SF commercial space ideal for retail, office, restaurant.

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Retail Spaces in Hannaford-Anchored Plaza

800 Islington St Units 10A & 10B, Portsmouth, NH 3801

$22 SF/Yr

10,660 sqft · $19,543/Mo

Retail and office spaces available in Portsmouth's West End.

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Downtown Office or Retail Space

66 State Street, Portsmouth, NH 3801

$2,500/Mo

595 sqft · $50 SF/Yr

Flexible 595± SF storefront-ready space on State Street with downtown pedestrian activity and consistent vehicular traffic.

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Retail Space on Route 1

2299 Lafayette Rd, Portsmouth, NH 3801

$14,500/Mo

7,000 sqft · $24 SF/Yr

7,000 SF retail space in high-visibility Portsmouth location.

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Two-Story Retail and Office Suite

72 Mirona Rd Suite 2, Portsmouth, NH 3801

$17 SF/Yr

3,331 sqft · $4,718/Mo

Two-story space with on-site parking and flexible layout for retail or office operations.

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Downtown Office Suites

25 Chestnut Street, Portsmouth, NH 3801

$20 SF/Yr

5,793 sqft · $9,655/Mo

Two move-in ready office suites with efficient floor plans and excellent natural light in Downtown Portsmouth.

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Retail and Office Building

72 Mirona Rd, Portsmouth, NH 3801

$17 SF/Yr

5,381 sqft · $7,847/Mo

Two-floor retail and office layout with ample parking and convenient highway access for a wide range of users.

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Portsmouth Office Space For Lease

500 Maplewood Ave Unit A, Portsmouth, NH 3801

$10 SF/Yr

3,921 sqft · $3,267/Mo

Versatile office space in Portsmouth, accessible from city or bypass.

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Retail End-Cap Space Available

451 High St, Somersworth, NH 3878

$14 SF/Yr

4,400 sqft · $5,133/Mo

4,400 SF end-cap space in busy retail strip center.

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Turnkey Florist Retail Space

1000 Woodbury Ave, Portsmouth, NH 3801

$2,500/Mo

856 sqft · $35 SF/Yr

Fully built-out florist retail space with greenhouses in Portsmouth.

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West End Office Space Available

801 Islington St Unit 33, Portsmouth, NH 3801

$19 SF/Yr

2,300 sqft · $3,641/Mo

Second-floor office space in Portsmouth's West End.

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Highly Visible Retail/Office Suite

21 Daniel Street, Portsmouth, NH 3801

$6,750/Mo

2,242 sqft · $36 SF/Yr

First-floor retail or office space with an added basement area, located just off Market Square for strong visibility.

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Retail Suites at Lilac Plaza

181-193B Wakefield St 183, Rochester, NH 3867

$18 SF/Yr

5,000 sqft · $7,500/Mo

Retail spaces for lease with planned renovations and upgrades.

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Downtown Portsmouth Modern Open Office

299 Hanover St First Floor, Portsmouth, NH 3801

$3,350/Mo

2,000 sqft · $20 SF/Yr

Modern 2000 sqft office space in downtown Portsmouth.

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Industrial-Flex Warehouse Suite

3-270 West Rd, Portsmouth, NH 3801

$15 SF/Yr

4,994 sqft · $6,242/Mo

Industrial and flex space with warehouse area, private offices, and high ceilings for efficient operations.

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Retail/Office Space Near UNH

71 Calef Hwy, Lee, NH 3861

$20 SF/Yr

3,000 sqft · $5,000/Mo

Turnkey retail or office space in Lee, NH.

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Industrial/Flex Space For Lease

270 West Rd 3, Portsmouth, NH 3801

$15 SF/Yr

4,994 sqft · $6,242/Mo

4,994± SF industrial/flex space near Route 1.

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Strafford County, NH Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Strafford County, NH with 208 listings featured on our commercial real estate exchange. The current inventory includes 1,628,653 square feet of properties with an estimated lease value of $2,122 /Mo.

Estimated lease rates for Commercial real estate in Strafford County, NH begin at $0.58 SF/Yr, with an average of $18 SF/Yr and extend to $140 SF/Yr.