Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent / SF / Yr
    $
    $
    Rent / Mo
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Mexico, MO Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Saint Louis, MO Louis, MO Kansas City, MO
    Office Space For Rent
    $300/Mo

    Office Space For Rent

    508 S Muldrow St, Mexico, MO 65265

    Basement office space with multiple offices, kitchenette, and lobby.

    • High Visibility Location: Situated on the only 4‑lane road through Mexico, ensuring maximum exposure.
    • Flexible Office Space: Lease one or all six offices.
    • Shared Office Space: 2,800+ sq ft basement office shared with Simply Real Estate.
    • Multiple Offices: Includes 6 private offices.
    • Essential Amenities: Equipped with a kitchenette, lobby, and 2 bathrooms.
    Updated: Aug 19, 2025
    View details
    Prime Retail Space Available
    $5 SF/Yr
    5,800 SF

    Prime Retail Space Available

    650 W Jackson St, Mexico, MO

    Retail space in the heart of Mexico, Missouri.

    • Located in the heart of Mexico, MO near downtown
    • Multiple points of ingress/egress through 2 main streets
    • Fantastic visibility
    • Located off signalized intersection next to Walgreen's
    • County seat of Audrain County
    Updated: Apr 1, 2024
    View details
    Warehouse & Office Space Rental
    Contact for pricing

    Warehouse & Office Space Rental

    Modern warehouse and office space with I-70 access.

    1000 S Elmwood Dr, Mexico, MO 65265
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 3 Active listings in Mexico, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 13 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Commercial Pad Sites For Lease
    Contact for pricing

    Commercial Pad Sites For Lease

    Two pad sites available in high-volume, grocery-anchored center.

    Mexico Gravel Rd, Columbia, MO
    View details
    Retail/Office Space For Lease
    $12 SF/Yr
    1,750 SF

    Retail/Office Space For Lease

    Retail or office space available for lease near Dollar General.

    1978-2020 N Bluff St, Fulton, MO
    View details
    Fulton Commercial Space For Lease
    Contact for pricing

    Fulton Commercial Space For Lease

    Commercial space available for lease in Fulton, Missouri.

    1978 N Bluff St, Fulton, MO 65251
    View details
    Retail Space in New Center
    Contact for pricing

    Retail Space in New Center

    Lease opportunities in new East Columbia shopping center.

    5414 Clark Ln, Columbia, MO 65202
    View details

    Explore Similar Spaces for Sale in Mexico, MO

    Consider Similar Space for Sale. We found 13 Spaces matching your search parameters.

    High-Visibility Commercial Building For Sale
    $160,000
    2,040 SF

    High-Visibility Commercial Building For Sale

    Versatile commercial building in high-traffic location with flexible layout.

    1108 E Liberty Street, Mexico, MO 65265
    View details
    Remodeled Commercial Space, Mexico, MO
    $598,000
    8,119 SF

    Remodeled Commercial Space, Mexico, MO

    Remodeled commercial property with high traffic and ample parking.

    1900 E Liberty Street, Mexico, MO 65265
    View details
    Pole Barn on Compact Lot
    Contact for pricing

    Pole Barn on Compact Lot

    2019 pole barn on 0.14-acre lot, ideal for storage.

    612 Fairground, Mexico, MO 65265
    View details
    Versatile Commercial Property in Mexico
    $395,000
    0.15 Acres

    Versatile Commercial Property in Mexico

    Two-level commercial property ideal for business ventures and events.

    105 N Coal Street, Mexico, MO 65265
    View details
    Farmland Auction in Mexico, Missouri
    Contact for pricing
    115.00 Acres

    Farmland Auction in Mexico, Missouri

    Two tracts of farmland offered at auction on April 21st.

    929 Audrain Road 929, Mexico, MO 65265
    View details
    Agricultural Land Near Highway J
    $300,000
    19.00 Acres

    Agricultural Land Near Highway J

    19+ acres of agricultural land with development potential.

    Highway J, Mexico, MO 65265
    View details
    Prime Commercial Lot For Sale
    $165,000
    0.82 Acres

    Prime Commercial Lot For Sale

    0.82-acre commercially zoned lot in high-traffic downtown location.

    303 S Jefferson Street, Mexico, MO 65265
    View details
    Turn-Key Bar and Pool Hall
    $172,000
    0.06 Acres

    Turn-Key Bar and Pool Hall

    Recently renovated bar/pool hall with potential living space.

    114 S Jefferson Street, Mexico, MO 65265
    View details
    Established Retail Center For Sale
    $4,499,692
    119,219 SF

    Established Retail Center For Sale

    Value-add opportunity in Mexico, MO, with long-term tenants.

    500-700 W Jackson St, Mexico, MO
    View details
    Agricultural Land Auction in Mexico, MO
    Contact for pricing
    5,009,400 SF

    Agricultural Land Auction in Mexico, MO

    Online and live auction featuring two land tracts.

    929 Audrain Road 929, Mexico, MO 65265
    View details
    Missouri Farmland with Ranch Home
    $950,000
    130.22 Acres

    Missouri Farmland with Ranch Home

    130+ acre Missouri farm with income potential and charming home.

    23274 Audrain Rd 324, Mexico, MO
    View details
    Former Equipment Rental Facility
    $247,000
    5,344 SF

    Former Equipment Rental Facility

    Main highway location with showroom, offices, and storage.

    1900 E Liberty St, Mexico, MO
    View details
    Large Industrial Facility For Sale
    Contact for pricing
    310,316 SF

    Large Industrial Facility For Sale

    310,316 sqft manufacturing/warehouse on 36 acres in Mexico, MO.

    5701 E Liberty St, Mexico, MO 65265
    View details

    Mexico, MO Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Mexico, MO with 3 listings featured on our commercial real estate exchange. The current inventory includes 5,800 square feet of properties with an estimated lease value of $5 SF/Yr.

    Estimated lease rates for Commercial real estate in Mexico, MO begin at $5 SF/Yr, with an average of $5 SF/Yr and extend to $5 SF/Yr.
    List
    Map

    Most Searched ZIP Codes in Mexico, MO

    • 65265

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!