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    Brookline, MO Commercial Real Estate for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    12 results
    Prime Retail Space in Republic
    $18 SF/Yr
    24,000 SF

    Prime Retail Space in Republic

    2510-2544 S. State Hwy MM, Republic, MO 65738

    Retail spaces available in a high-growth Republic, MO location.

    • Hard corner location with access on Hwy MM and Sawyer Rd.
    • Adjacent to a 1.4 million/SF Amazon Fulfillment Center.
    • Located in a fast‑growing Republic, MO market.
    • Projected increase to over 37,000 Cars Per Day in 5 years.
    • Part of the Iron Grain District mixed‑use development.
    Updated: Nov 21, 2025
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    New Retail Spaces For Lease
    $10 SF/Yr
    1,822 SF

    New Retail Spaces For Lease

    3401 W Old Stone Ave, Republic, MO

    New mixed-use retail spaces available near Amazon distribution center.

    • Located near Amazon's new 1,400,000± SF distribution center
    • High‑end, mixed‑use new construction
    • Hard‑corner signalized intersection
    • Landlord provides white box finish or infill allowance equal to $30 PSF (to qualified tenant)
    • Republic is one of the fastest growing communities in the State of Missouri
    Updated: Nov 24, 2025
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    Republic Office Space For Rent
    $15 SF/Yr
    1,394 SF

    Republic Office Space For Rent

    Office spaces available, ranging from 127 to 1,606 SF.

    201-267 W US Hwy 60, Republic, MO
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    Republic Industrial Building For Lease
    $8 SF/Yr
    52,120 SF

    Republic Industrial Building For Lease

    52,120 SF industrial building in Republic, Missouri available October 2025.

    3135 Hankins Road, Republic, MO 65619
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    Republic Industrial Building For Lease
    $7 SF/Yr

    Republic Industrial Building For Lease

    75,160 SF industrial building in Republic, Missouri.

    3130 E Hankins Rd, Republic, MO 65738
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    Retail Space on US-60
    $16 SF/Yr
    2,500 SF

    Retail Space on US-60

    Retail space available in Republic, Missouri with US-60 frontage.

    315 US Highway 60 E, Republic, MO
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    Retail Space with Ample Parking
    $16 SF/Yr
    1,500 SF

    Retail Space with Ample Parking

    Retail space featuring a signalized corner and pylon sign.

    562-566 E Harrison St, Republic, MO
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    Prime Commercial Land for Lease
    Contact for pricing

    Prime Commercial Land for Lease

    Exceptional property with high visibility and easy access.

    1600 U.S. 60, Republic, MO 65738
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    Warehouse Space Near Distribution Center
    $8 SF/Yr
    75,000 SF

    Warehouse Space Near Distribution Center

    Warehouse space available near major distribution and mixed-use developments.

    3020 N York Ave, Republic, MO
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    Republic Industrial Building For Lease
    Contact for pricing
    52,120 SF

    Republic Industrial Building For Lease

    Industrial building for lease in Republic, Missouri, available October 2025.

    3135 E Hankins Rd, Republic, MO 65738
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    Prime Commercial Space For Lease
    Contact for pricing

    Prime Commercial Space For Lease

    Commercial property for lease with high visibility and ample parking.

    542 E Harrison St, Republic, MO 65738
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    Retail Pad Site For Lease
    Contact for pricing

    Retail Pad Site For Lease

    Land lease opportunity next to future Andy's Frozen Custard.

    Republic, 1355 US Hwy 60, Republic, MO 65738
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    Based on your search, we've compiled 75 Potential Opportunities for your consideration. Besides 12 Active listings in Brookline, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 59 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    West Springfield Retail Space Available
    Contact for pricing
    150,000 SF

    West Springfield Retail Space Available

    Retail space for lease near Walmart Super Center.

    3600 West Sunshine Street, Springfield, MO 65807
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    Retail Space For Lease
    $9 SF/Yr
    4,200 SF

    Retail Space For Lease

    Retail space available for lease at $9.00/sf NNN.

    4032 W Lark St, Battlefield, MO
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    Battlefield MO Executive Office Space
    Contact for pricing

    Battlefield MO Executive Office Space

    Executive office space with multiple offices and conference rooms available.

    4852 West Byp, Battlefield, MO 65619
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    Springfield Commercial Property for Rent
    Contact for pricing

    Springfield Commercial Property for Rent

    Commercial property available for rent in Springfield, Missouri.

    3600 W Sunshine St, Springfield, MO 65807
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    Explore Similar Spaces for Sale in Brookline, MO

    Consider Similar Space for Sale. We found 59 Spaces matching your search parameters.

    Prime Commercial Land Opportunity
    $335,000
    1.05 Acres

    Prime Commercial Land Opportunity

    1.05 acre commercial land near Amazon Distribution Center.

    2756 N Brookline Avenue, Republic, MO 65619
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    Highway Frontage Commercial Lot
    $419,000
    0.94 Acres

    Highway Frontage Commercial Lot

    Prime commercial lot on Highway 60 in Republic, Missouri.

    U.S. Highway 60 E, Republic, MO 65738
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    Highway Frontage Commercial Lot
    $419,000
    0.94 Acres

    Highway Frontage Commercial Lot

    Commercial lot on Highway 60 in Republic, Missouri.

    U.S. Highway 60 E, Republic, MO 65738
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    Commercial Lot on Highway 60
    $419,000
    0.94 Acres

    Commercial Lot on Highway 60

    Prime commercial lot with highway frontage in Republic, Missouri.

    U.S. Highway 60 E, Republic, MO 65738
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    Republic Commercial Office Space Available
    $789,900
    0.64 Acres

    Republic Commercial Office Space Available

    Versatile office space suitable for various professional service providers.

    820 S Illinois Avenue, Republic, MO 65738
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    74.27 Acres in Republic, MO
    $750,000
    74.27 Acres

    74.27 Acres in Republic, MO

    74.27 acres in Republic, Missouri, ideal for agricultural use.

    4507 S Farm Road 71, Republic, MO 65738
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    Republic, MO School Building
    $689,000
    0.79 Acres

    Republic, MO School Building

    7,988 SF building with classrooms and multiple restrooms.

    220 N Cedar Avenue, Republic, MO 65738
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    Republic, MO Building Tract
    $189,000
    10.50 Acres

    Republic, MO Building Tract

    Country building tracts with open space and build-ready potential.

    000 Tract8 W Farm Road 174, Republic, MO 65738
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    Republic MO Office Building For Sale
    $415,000
    6,491 SF

    Republic MO Office Building For Sale

    Office building with multiple offices, conference room, and parking.

    209-213 North Main Street, Republic, MO 65738
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    Prime Commercial Land in Republic
    $499,900
    0.67 Acres

    Prime Commercial Land in Republic

    High-visibility commercial land with C-2 zoning in rapidly growing Republic.

    980 E Us Highway 60, Republic, MO 65738
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    Republic, MO Building Tract
    $183,600
    10.20 Acres

    Republic, MO Building Tract

    Country building tracts with open space and build-ready potential.

    000 Tract5 W Farm Road 174, Republic, MO 65738
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    Prime Commercial Lot in Republic
    $499,000
    1.18 Acres

    Prime Commercial Lot in Republic

    C-1 zoned commercial lot ready for development in Republic, MO.

    1548 E Hamilton Street, Republic, MO 65738
    View details

    Brookline, MO Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Brookline, MO with 12 listings featured on our commercial real estate exchange. The current inventory includes 158,336 square feet of properties with an estimated lease value of $92 SF/Yr.

    Estimated lease rates for Commercial real estate in Brookline, MO begin at $8 SF/Yr, with an average of $13 SF/Yr and extend to $18 SF/Yr.
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    Browse Commercial real estate for Lease Near Brookline, MO

    Popular Searches in Brookline, MO

    Most Searched ZIP Codes in Brookline, MO

    • 65738
    • 65619

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