Frederick County, MD Commercial real estate for Rent & Lease

Frederick Commercial Space with Drive-Through

$18 SF/Yr

133,729 SF

Frederick Commercial Space with Drive-Through

198 Thomas Johnson Dr, Frederick, MD 21701

Versatile commercial space in Frederick with high visibility and accessibility.

Highly visible location in Frederick City with heavy traffic flow.
Versatile 2,410 SF space suitable for various businesses.
Benefit from the drive‑through access.
ADA accessibility with main‑level ramp.
Large parking lot.

Updated: Jan 3

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Charming Frederick Office Space Available

$800 / Mo

20,473 SF

Charming Frederick Office Space Available

3390 Urbana Pike Unit, Frederick, MD 21704

Sophisticated office space in a character-rich building with negotiable lease.

Strategic location offers accessibility and a prestigious presence.
Dedicated parking lot provides convenience for clients and employees.
High ceilings and abundant natural light create an uplifting and inspiring atmosphere.
Opportunity to create a bespoke space tailored to specific business needs.
Expansive lot (nearly half an acre) provides ample space.

Updated: Dec 21, 2025

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$800 / Mo

20,473 SF

Charming Frederick Office Space Available

Exquisite commercial lease opportunity with historic elegance and modern functionality.

3390 Urbana Pike Unit, Frederick, MD 21704

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$800 / Mo

20,473 SF

Charming Frederick Office Space Available

Sophisticated office space in a character-rich building with parking.

3390 Urbana Pike Unit, Frederick, MD 21704

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$800 / Mo

20,473 SF

Charming Frederick Office Space Available

Sophisticated office space in a character-rich building with negotiable lease.

3390 Urbana Pike Unit, Frederick, MD 21704

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$18 SF/Yr

133,729 SF

Frederick Commercial Space with Drive-Through

Versatile commercial space in Frederick with high visibility and accessibility.

198 Thomas Johnson Dr, Frederick, MD 21701

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$3,000 / Mo

New Townhome Near Historic Frederick

Brand new townhome with modern amenities and convenient location.

406 Carroll Walk Ave, Frederick, MD 21701

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$8 SF/Yr

Frederick Warehouse Retail Sublease Available

4,800 SF warehouse retail sublease in Frederick, Maryland.

622 N Market St, Frederick, MD 21701

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$2,120 / Mo

Office Space in Frederick, MD

Office space available for lease in Frederick, Maryland.

6550 Mercantile Dr E, Frederick, MD 21703

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$20 SF/Yr

1,742 SF

Downtown Frederick Office Space

Charming office building in historic Downtown Frederick.

22 2Nd St E, Frederick, MD 21701

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$18 SF/Yr

133,729 SF

Frederick Commercial Space For Lease

Highly visible commercial space in Frederick, ready for immediate occupancy.

198 Thomas Johnson Dr, Frederick, MD 21701

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$18 SF/Yr

133,729 SF

Frederick Commercial Space with Drive-Through

Versatile commercial space in Frederick, ideal for various businesses.

198 Thomas Johnson Dr, Frederick, MD 21701

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$18 SF/Yr

133,729 SF

Frederick Commercial Space with Drive-Through

Versatile commercial space in Frederick, ideal for various businesses.

198 2Nd St, Frederick, MD 21701

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$16 SF/Yr

43,124 SF

Mount Airy Office Space Lease

Office spaces available for lease in Mount Airy, Maryland.

1311 Main St, Mount Airy, MD 21771

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$21 SF/Yr

Office Condo For Lease

Office condo with conference room, open area, and kitchen.

241 4Th St E, Frederick, MD 21701

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$3,875 / Mo

19,602 SF

Urbana Pike Retail/Office Space

Professional suites off 355 in Urbana, available in 2023.

3535 Urbana Pike, Frederick, MD 21704

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$16 SF/Yr

Frederick Medical/Office Space Available

3,648 SF medical/office space for lease in Frederick, MD.

604 Solarex Ct, Frederick, MD 21703

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Downtown Frederick Office Space Available

$18 SF/Yr

871 SF

Downtown Frederick Office Space Available

Spacious office suite in a prime downtown Frederick location.

5 S Market St Unit, Frederick, MD 21701

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$18 SF/Yr

871 SF

Downtown Frederick Office Space Available

Spacious office suite in a prime downtown Frederick location.

5 S Market St Unit, Frederick, MD 21701

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$5,935 / Mo

19,602 SF

Urbana Pike Retail/Office Space

Retail and office suites available for lease in Frederick, MD.

3535 Urbana Pike, Frederick, MD 21704

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$3,750 / Mo

12,632 SF

Renovated Commercial Property in Urbana

Renovated commercial property suitable for retail or office use.

8832 Urbana Church Rd, Frederick, MD 21704

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$2,900 / Mo

10,019 SF

Mount Airy Professional Office Suite

Professional office suite in Mt. Airy, MD, available for lease.

602 Center St, Mount Airy, MD 21771

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$400 / Mo

2,614 SF

Office Space in Frederick, MD

Office property for lease in Frederick, Maryland.

322 W Patrick St, Frederick, MD 21701

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$2,400 / Mo

1,200 SF

Updated Duplex in Downtown Frederick

Charming duplex with updated features and a convenient downtown location.

608 Trail Ave, Frederick, MD 21701

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Frederick County, MD Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Frederick County, MD with 567 listings featured on our commercial real estate exchange. The current inventory includes 68,542,035,312 square feet of properties with an estimated lease value of $20,554.

Estimated lease rates for Commercial Real Estate in Frederick County, MD begin at $7 SF/Yr, with an average of $321 /Mo and extend to $5,935 /Mo.

In Frederick County, MD, current lease rates show:

Office Properties & Spaces positioned at $413
Office space measuring $420
Retail properties assessed at $793
Individual retail properties calculated at $858

Frederick County, MD Commercial Real Estate for Lease

Frederick Commercial Space with Drive-Through

Versatile commercial space in Frederick with high visibility and accessibility.

Charming Frederick Office Space Available

Sophisticated office space in a character-rich building with negotiable lease.

Charming Frederick Office Space Available

Charming Frederick Office Space Available

Charming Frederick Office Space Available