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Florence, MA

Florence, MA Commercial Real Estate for Lease

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Hadley, MA Easthampton, MA Hatfield, MA

45 properties

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Downtown Northampton Office Space

Updated: Nov 13, 2025

Downtown Northampton Office Space

20 Hampton Ave, Northampton, MA 01060

$2,800/Mo

925 sqft · $36 SF/Yr

Prime downtown Northampton location offers excellent visibility and accessibility.
Six private offices provide ample space for a growing business.
Modern commercial office suite suitable for establishing a professional presence.
Fully equipped break room enhances employee satisfaction.
Welcoming waiting area creates a positive first impression.

Second-Floor Office Suite

Updated: Jun 11

Second-Floor Office Suite

304 Pleasant St, Northampton, MA 1060

$16 SF/Yr

3,600 sqft · $4,800/Mo

Vacant 3,600 SF second‑level office suite with full‑floor, single‑tenant occupancy
Located at 300 Pleasant Street in Northampton, MA 01060
Flexible layout suitable for professional, administrative, medical, or office uses
Lease rate is $4,800 per month plus utilities ($16/SF annually)
Immediate availability for occupancy

Downtown Northampton Commercial Office Space

Downtown Northampton Commercial Office Space

20 Hampton Ave, Northampton, MA 01060

$1,000/Mo

Prime commercial office space in vibrant downtown Northampton.

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Move-in Ready Retail/Office Spaces

Move-in Ready Retail/Office Spaces

123 Hawley St, Northampton, MA 1060

$1,200/Mo

1,100 sqft · $13 SF/Yr

Affordable retail and office spaces available for immediate occupancy.

Turnkey Bank Branch For Rent

Turnkey Bank Branch For Rent

21 Locust St, Northampton, MA 1060

$22 SF/Yr

3,000 sqft · $5,500/Mo

Turnkey bank branch location with drive-up, ATM, and offices.

Charming Office Space in Northampton

Charming Office Space in Northampton

46 Main St #Front, Northampton, MA 1060

$650/Mo

419 sqft · $18 SF/Yr

Office space with exposed brick, high ceilings, and natural light.

Main Street Commercial Spaces Available

Main Street Commercial Spaces Available

78 Main St, Northampton, MA 1060

$20 SF/Yr

2,638 sqft · $4,396/Mo

Commercial spaces for rent on Main Street, Northampton, MA.

Second-Floor Office Suite

Second-Floor Office Suite

234236-241 King St, Northampton, MA 1060

$1,975/Mo

900 sqft · $26 SF/Yr

Second-floor suite with three private offices, conference room, waiting area, and private restroom for office tenants.

Prime Downtown Retail Space Available

Prime Downtown Retail Space Available

158 Main St, Northampton, MA 1060

$4,000/Mo

1,800 sqft · $26 SF/Yr

First-floor retail space in a prime downtown location.

Downtown Northampton Commercial Space

Downtown Northampton Commercial Space

140 Main St Unit 2, Northampton, MA 1060

$2,100/Mo

Commercial space suitable for salon, spa, wellness, or professional service.

Private Office Suites with Shared Restrooms

Private Office Suites with Shared Restrooms

1-118 Main St, Northampton, MA

$500/Mo

Two private office suites with hardwood floors and gas heat, available individually or combined.

First-Floor Office Suite

First-Floor Office Suite

5-139 Damon Rd, Northampton, MA 1060

$210 SF/Yr

110 sqft · $1,925/Mo

Affordable first-floor office space in a well-kept building with ample off-street parking and utilities included.

Downtown Northampton Retail Space Available

Downtown Northampton Retail Space Available

30 Crafts Ave, Northampton, MA

$15 SF/Yr

5,186 sqft · $6,482/Mo

Prime retail opportunity with high visibility and ample parking.

Retail Space with Vaults

Retail Space with Vaults

135 Main St 1, Northampton, MA 1060

$2,975/Mo

767 sqft · $46 SF/Yr

First-floor retail space with basement storage and unique vault features.

Retail Space with High Visibility

Retail Space with High Visibility

104 Damon Road #C, Northampton, MA 1060

$2,250/Mo

Retail space with showroom, storage, and convenient highway access.

Professional Office Suite For Rent

Professional Office Suite For Rent

8 N King St, Northampton, MA

$25 SF/Yr

1,320 sqft · $2,750/Mo

1,320 SF office suite with excellent highway access.

Downtown Northampton Office Space Available

Downtown Northampton Office Space Available

50 Center St. 7, Northampton, MA 01060

$500/Mo

145 sqft · $41 SF/Yr

Second-floor office space with natural light and shared amenities.

Retail Space Near I-91

Retail Space Near I-91

5 Fulton Ave, Northampton, MA

$30 SF/Yr

1,443 sqft · $3,607/Mo

Retail units available in high-traffic location near I-91.

Downtown Northampton Second-Floor Office Space

Downtown Northampton Second-Floor Office Space

50 Center St. 6, Northampton, MA 01060

$500/Mo

240 sqft · $25 SF/Yr

240 SF office space with shared amenities in downtown Northampton.

Downtown Northampton Office Space Available

Downtown Northampton Office Space Available

110 Main St. 2A, Northampton, MA 01060

$800/Mo

375 sqft · $25 SF/Yr

Second-floor office space in downtown Northampton for rent.

Commercial Space with High Ceilings

Commercial Space with High Ceilings

78 Main St, Northampton, MA 1060

$20 SF/Yr

Commercial space suitable for restaurant or retail venture.

Florence Office Space For Rent

Florence Office Space For Rent

41 Main St #B2, Northampton, MA 1062

$750/Mo

1 sqft · $9,000 SF/Yr

900 SF office space in central Florence.

Retail Space on Main Street

Retail Space on Main Street

135 Main St St. 1, Northampton, MA 01060

$2,975/Mo

First-floor retail space with basement storage in historic building.

Downtown Northampton Retail Space Available

Downtown Northampton Retail Space Available

180 Main, Northampton, MA 1060

$29 SF/Yr

Prime retail space in high-traffic downtown Northampton location.

Florence, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Florence, MA with 45 listings featured on our commercial real estate exchange. The current inventory includes 48,002 square feet of properties with an estimated lease value of $49,220.

Estimated lease rates for Commercial real estate in Florence, MA begin at $8 SF/Yr, with an average of $1,295 /Mo and extend to $23,700.

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