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Florence, MA

Florence, MA Commercial Real Estate for Lease

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Hadley, MA Hatfield, MA Easthampton, MA South Hadley, MA Southampton, MA Amherst, MA Holyoke, MA Chicopee, MA

47 properties

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Second-Floor Office Suite

Updated: Jun 11

Second-Floor Office Suite

304 Pleasant St, Northampton, MA 01060

$16 SF/Yr

3,600 sqft

Vacant 3,600 SF second‑level office suite with full‑floor, single‑tenant occupancy
Located at 300 Pleasant Street in Northampton, MA 01060
Flexible layout suitable for professional, administrative, medical, or office uses
Lease rate is $4,800 per month plus utilities ($16/SF annually)
Immediate availability for occupancy

Medical Office Suites with Parking

Updated: Jul 24

Medical Office Suites with Parking

264 Elm St B&c, Northampton, MA 01060

$22 SF/Yr

1,285 sqft

First- and second‑floor medical office space in a 1949 building with ADA accessibility
2 spaces available on the first floor totaling 1,300 SF, with Unit B at 920 SF and Unit C at ~325 SF
Unit B includes a waiting room, reception area, 3 exam rooms, and 2 offices; formerly used as a dental practice
Second floor offers 1,427 SF with reception area and 5 private offices (some include sinks)
Over 40 on‑site parking spaces available for the property

Renovated Lower-Level Office Suite

Renovated Lower-Level Office Suite

41 Main St B1, Northampton, MA 01062

$1,500/Mo

5–8 people 1,300 sqft Built 1977

General Business

Renovated general business office with private offices, conference room, and kitchenette; utilities and dumpster use paid by tenant.

Office Units with Shared Amenities

Office Units with Shared Amenities

90 Conz Street, Northampton, MA 01060

$285-$950/Mo

21–35 people 5,258 sqft Built 1986

Highway access

Tenants can use a common conference room, waiting area, kitchenette, restrooms, and copy machine.

Common waiting area Restrooms Kitchenette Conference room

Turnkey Office Space

Turnkey Office Space

32 Industrial Dr E, Northampton, MA 01060

$17 SF/Yr

28–46 people 7,000 sqft Built 1986

Highway access

Turnkey second-floor office space with shared conference rooms, kitchen/break room, and ample parking included.

Parking Shared conference rooms Kitchen/break room

Retail Space with Public Parking

Retail Space with Public Parking

20A Crafts Ave., Northampton, MA 01060

$1,500/Mo

680 sqft Built 2009

Commercially zoned space is near public and on-street parking options.

Retail Space with Display Windows

Retail Space with Display Windows

158 Main Street, Northampton, MA 01060

$4,000/Mo

2,400 sqft Floor 1 Built 1900

White-box storefront with basement storage, climate control, and the option to divide the space between two compatible businesses.

Sprinklered Dual minisplit HVAC system Sprinkler system

Office Unit with Elevator Access

Office Unit with Elevator Access

3-100 Main St, Northampton, MA

$5,000/Mo

10–16 people 2,500 sqft Floor 3

5 private offices 1 meeting room

Third-floor office space offers private rooms, meeting space, a kitchenette, restrooms, and flexible open workspace.

Waiting room Kitchenette Shower

Main Street Commercial Spaces Available

Main Street Commercial Spaces Available

78 Main St, Northampton, MA 01060

$20 SF/Yr

2,638 sqft Built 1900

Commercial spaces for rent on Main Street, Northampton, MA.

Florence Office Space For Rent

Florence Office Space For Rent

41 Main St B2, Northampton, MA 01062

$750/Mo

3–6 people 900 sqft Built 1977

900 SF office space in central Florence.

Downtown Northampton Office Space Available

Downtown Northampton Office Space Available

50 Center St. #6, Northampton, MA 01060

$500/Mo

1 person 240 sqft Built 1900

Second-floor office space in downtown Northampton with shared amenities.

Lower Level Office Suite

Lower Level Office Suite

B2-41 Main St, Northampton, MA

$750/Mo

3–6 people 900 sqft

General Business

Lower level suite with three private offices and open workspace, zoned General Business.

Shared Office Suite

Shared Office Suite

17 New South, Unit 201, Northampton, MA 01060

$850/Mo

1 person 180 sqft Built 1900

Office suite within a shared downtown suite with utilities included, an off-street parking space, and shared waiting room access.

Renovated Office Suite with Kitchenette

Renovated Office Suite with Kitchenette

B1-41 Main St, Northampton, MA

Triple net (NNN)

$1,500/Mo

5–8 people 1,300 sqft

General Business

Lower-level office suite offers four private offices, conference space, open workspace, and a kitchenette.

4 private offices 2 restrooms Conference room Large open workspace

Charming Office Space in Northampton

Charming Office Space in Northampton

46 Main St Front, Northampton, MA 01060

$650/Mo

1–2 people 419 sqft Built 1900

Unique office space with exposed brick, high ceilings, and natural light.

First-Floor Office Unit

First-Floor Office Unit

201-17 New South St, Northampton, MA 01062

$850/Mo

1 person 180 sqft Floor 1

Downtown office suite with shared reception, restroom, internet, utilities, and reserved off-street parking.

1 parking space Utilities included Internet included Shared waiting area

Northampton Industrial Park Office Space

Northampton Industrial Park Office Space

32 Industrial Dr E, Northampton, MA 01060

$18 SF/Yr

28–46 people 7,000 sqft Built 1986

Turnkey office space for lease near downtown Northampton.

Third-Floor Office Suite with Elevator

Third-Floor Office Suite with Elevator

100 Main Street, Unit 3, Northampton, MA 01060

$5,000/Mo

10–16 people 2,500 sqft Built 1900

Third-floor office suite features five private offices, a conference room, flex workspace, kitchenette, and two restrooms.

Second-Floor Office Suite

Second-Floor Office Suite

50 Center St., #7, Northampton, MA 01060

$500/Mo

1 person 145 sqft Built 1900

Move-in ready second-floor office suite with skylight natural light, shared waiting room, and restroom; utilities included.

Affordable Commercial Space For Rent

Affordable Commercial Space For Rent

518 Pleasant Street, Unit 12, Northampton, MA 01060

$500/Mo

2–3 people 550 sqft Built 1900

Third-floor 550 sqft commercial space near Interstate 91.

Second-Floor Office Unit

Second-Floor Office Unit

7-50 Center St, Northampton, MA 01060

$500/Mo

1 person 145 sqft Floor 2

Public transit

Move-in-ready workspace with skylight illumination, shared reception and restroom access, plus electricity and heat included.

Shared waiting room Restroom Skylight

Second-Floor Office Unit

Second-Floor Office Unit

6-50 Center St, Northampton, MA 01060

$500/Mo

1 person 240 sqft Floor 2

Public transit

Move-in-ready office space with shared reception and restroom access, plus electricity and heat included.

Shared waiting room Shared restroom Public parking Parking garage

Retail Storefront with Basement

Retail Storefront with Basement

141 Main Street, Northampton, MA 01060

$3,000/Mo

1,648 sqft Built 1900

Street-level retail space includes first-floor and basement areas, with upgraded electrical and new HVAC.

Office Suite with Skylights

Office Suite with Skylights

241 King St #234/236, Northampton, MA 01060

$1,975/Mo

3–6 people 900 sqft Built 1980 Floor 2

3 private offices 1 meeting room Highway access

A second-floor workspace includes private offices, a conference room, an administrative area, and a dedicated restroom.

Florence, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Florence, MA with 47 listings featured on our commercial real estate exchange. The current inventory includes 186,483 square feet of properties with an estimated lease value of $710.26.

Estimated lease rates for Commercial real estate in Florence, MA begin at $10 SF/Yr, with an average of $24.49 SF/Yr and extend to $56.67 SF/Yr.

Florence, MA CRE market trends — vacancy, lease rates and price per SF, updated monthly

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