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Florence, MA

Florence, MA Commercial Real Estate for Lease

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Hadley, MA Easthampton, MA Hatfield, MA South Hadley, MA Southampton, MA Amherst, MA Holyoke, MA Chicopee, MA

55 properties

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Second-Floor Office Suite

Updated: Jun 11

Second-Floor Office Suite

304 Pleasant St, Northampton, MA 01060

$16 SF/Yr

3,600 sqft

Vacant 3,600 SF second‑level office suite with full‑floor, single‑tenant occupancy
Located at 300 Pleasant Street in Northampton, MA 01060
Flexible layout suitable for professional, administrative, medical, or office uses
Lease rate is $4,800 per month plus utilities ($16/SF annually)
Immediate availability for occupancy

Medical Office Suites with Parking

Updated: Jul 24

Medical Office Suites with Parking

264 Elm St B&c, Northampton, MA 01060

$22 SF/Yr

1,285 sqft

First- and second‑floor medical office space in a 1949 building with ADA accessibility
2 spaces available on the first floor totaling 1,300 SF, with Unit B at 920 SF and Unit C at ~325 SF
Unit B includes a waiting room, reception area, 3 exam rooms, and 2 offices; formerly used as a dental practice
Second floor offers 1,427 SF with reception area and 5 private offices (some include sinks)
Over 40 on‑site parking spaces available for the property

Retail Space with Display Windows

Retail Space with Display Windows

158 Main St, Northampton, MA 01060

$4,000/Mo

2,400 sqft

Downtown storefront with flexible layout, basement storage, building systems, and dedicated employee restroom.

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Renovated Lower-Level Office Suite

Renovated Lower-Level Office Suite

41 Main St B1, Northampton, MA 01062

$1,500/Mo

1,300 sqft

Renovated general business office with private offices, conference room, and kitchenette; utilities and dumpster use paid by tenant.

Turnkey Office Space

Turnkey Office Space

32 Industrial Dr E, Northampton, MA 01060

$17 SF/Yr

7,000 sqft

Turnkey second-floor office space with shared conference rooms, kitchen/break room, and ample parking included.

Main Street Commercial Spaces Available

Main Street Commercial Spaces Available

78 Main St, Northampton, MA 01060

$20 SF/Yr

2,638 sqft

Commercial spaces for rent on Main Street, Northampton, MA.

Office Unit with Elevator Access

Office Unit with Elevator Access

3-100 Main St, Northampton, MA

$5,000/Mo

2,500 sqft

Third-floor office space offers private rooms, meeting space, a kitchenette, restrooms, and flexible open workspace.

Second-Floor Office Suite

Second-Floor Office Suite

234236-241 King St, Northampton, MA 01060

$1,975/Mo

900 sqft

Second-floor suite with three private offices, conference room, waiting area, and private restroom for office tenants.

Florence Office Space For Rent

Florence Office Space For Rent

41 Main St B2, Northampton, MA 01062

$750/Mo

900 sqft

900 SF office space in central Florence.

Charming Office Space in Northampton

Charming Office Space in Northampton

46 Main St Front, Northampton, MA 01060

$650/Mo

419 sqft

Unique office space with exposed brick, high ceilings, and natural light.

Lower Level Office Suite

Lower Level Office Suite

B2-41 Main St, Northampton, MA

$750/Mo

900 sqft

Lower level suite with three private offices and open workspace, zoned General Business.

Industrial Flex Space with Offices

Industrial Flex Space with Offices

14 Easthampton Rd, Northampton, MA 01060

$10 SF/Yr

7,700 sqft 1.00 AC lot

Updated flex space includes private offices, reception and workshop areas plus six drive-in bays and up to 18-foot ceilings.

Renovated Office Suite with Kitchenette

Renovated Office Suite with Kitchenette

B1-41 Main St, Northampton, MA

$1,500/Mo

1,300 sqft

Lower-level office suite offers four private offices, conference space, open workspace, and a kitchenette.

First-Floor Office Unit

First-Floor Office Unit

201-17 New South St, Northampton, MA 01062

$1,000/Mo

180 sqft

Downtown office suite with shared reception, restroom, internet, utilities, and reserved off-street parking.

Third-Floor Office Suite with Elevator

Third-Floor Office Suite with Elevator

100 Main Street, Unit 3, Northampton, MA 01060

$5,000/Mo

2,500 sqft

Third-floor office suite features five private offices, a conference room, flex workspace, kitchenette, and two restrooms.

Retail Storefront with Basement

Retail Storefront with Basement

141 Main Street, Northampton, MA 01060

$3,000/Mo

1,648 sqft

Street-level retail space includes first-floor and basement areas, with upgraded electrical and new HVAC.

Storefront Space with Two Restrooms

Storefront Space with Two Restrooms

141 Damon Rd C, Northampton, MA 01060

$12 SF/Yr

700 sqft

GB-zoned retail space near I-91 with natural gas heating and hot water.

Retail Space with Vaults

Retail Space with Vaults

135 Main St 1, Northampton, MA 01060

$2,750/Mo

767 sqft

First-floor retail space with basement storage and unique vault features.

Affordable Commercial Space For Rent

Affordable Commercial Space For Rent

518 Pleasant Street, Unit 12, Northampton, MA 01060

$500/Mo

550 sqft

Third-floor 550 sqft commercial space near Interstate 91.

Second-Floor Office Suite

Second-Floor Office Suite

50 Center St., #7, Northampton, MA 01060

$500/Mo

145 sqft

Move-in ready second-floor office suite with skylight natural light, shared waiting room, and restroom; utilities included.

Shared Office Suite

Shared Office Suite

17 New South, Unit 201, Northampton, MA 01060

$1,000/Mo

180 sqft

Office suite within a shared downtown suite with utilities included, an off-street parking space, and shared waiting room access.

Downtown Northampton Office Space Available

Downtown Northampton Office Space Available

50 Center Street, Unit 7, Northampton, MA 01060

$500/Mo

240 sqft

Second-floor office space in downtown Northampton with shared amenities.

Commercial Lease

Commercial Lease

241 King St, #234/236, Northampton, MA 01060

$1,975/Mo

900 sqft

Office Units · 900 SF

First-Floor Office Suite

First-Floor Office Suite

139 Damon, Unit 11, Northampton, MA 01060

$500/Mo

190 sqft

Affordable first-floor office space in a well-kept building with ample off-street parking and included utilities.

Florence, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Florence, MA with 55 listings featured on our commercial real estate exchange. The current inventory includes 202,799 square feet of properties with an estimated lease value of $1,261.

Estimated lease rates for Commercial real estate in Florence, MA begin at $10 SF/Yr, with an average of $36.04 SF/Yr and extend to $210 SF/Yr.

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