Mayfield, KY Commercial Real Estate for Lease

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Fenced Flex Space with Loading Doors
Updated: Jan 11
Fenced Flex Space with Loading Doors

280 Luisa Lane, Mayfield, KY 42066

$4,000/Mo
12,000 sqft 3.24 AC lot
12,000 square feet on 3.24 fenced acres
Less than one mile from I‑69 and just off US Hwy 121
Three roll‑up garage doors for loading and logistics
Two 200‑amp power services plus one 100‑amp service
Enclosed upstairs loft/work area of approximately 2,560 square feet
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Retail Suite with Office Layout
Updated: Sep 12, 2025
Retail Suite with Office Layout

1522 Cuba Road, Mayfield, KY 42066

$1,500/Mo
1,500 sqft 0.44 AC lot
1,500 SF commercial suite available for lease
Four offices plus a large reception area
Suitable for office or retail use
B‑1 zoning
Natural gas heating and central air
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Four-Office Commercial Suite
Four-Office Commercial Suite

1522 Cuba Rd, Mayfield, KY 42066

$1,500/Mo

Lease-ready space combines private offices with a spacious reception area and supports office or retail occupancy.

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Based on your search, we've compiled 58 Potential Opportunities for your consideration. Besides 3 Active listings in Mayfield, KY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 51 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space
Medical Office Space

205 Ash Street, Benton, KY 42025

$5,550/Mo
6,324 sqft 0.86 AC lot

Configured for healthcare operations with reception, exam rooms, conference rooms, lab space, storage, and parking.

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NNN Dollar General Store
NNN Dollar General Store

2675 Main Street, Benton, KY 42025

Contact for pricing
9,026 sqft

Single-tenant Dollar General property offered on a NNN lease with no landlord responsibilities.

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Vacant Flex Space with Pull-Through Access
Vacant Flex Space with Pull-Through Access

1057 KY-381, Sedalia, KY 42079

$2,000/Mo
4,480 sqft 0.50 AC lot

Open, vacant commercial space includes utility service, heating, a bathroom, and multiple large sliding-door entrances.

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Vacant Flex Space with Pull-Through Access
Vacant Flex Space with Pull-Through Access

1057 KY 381, Sedalia, KY 42079

$2,000/Mo

Open metal building with electric service, heat, a bathroom, and multiple sliding-door entrances.

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Similar Spaces for Sale in Mayfield, KY

Consider Similar Space for Sale. We found 51 Spaces matching your search parameters.

Updated Medical Office Building
Updated Medical Office Building

1002 Cuba Road, Mayfield, KY 42066

$845,000
8,444 sqft 0.36 AC lot

Flexible commercial layout with reception, multiple work areas, upstairs finished space, and open parking.

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Flex Space with Office
Flex Space with Office

900 S Commonwealth Dr, Mayfield, KY 42066

$1,175,000
3,596 sqft 1.90 AC lot

Commercial facility combines finished office areas with warehouse functionality and roll-up access under one roof.

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Steel Flex Space with Offices
Steel Flex Space with Offices

280 Luisa Lane, Mayfield, KY 42066

$539,000
13,922 sqft 3.24 AC lot

C-1-zoned facility combines office areas, loading access, and flexible industrial workspace on a fenced commercial site.

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Medical Office Building with Reception
Medical Office Building with Reception

1002 Cuba Rd, Mayfield, KY 42066

$845,000
8,444 sqft

Updated interior includes multiple work areas, reception space, restrooms, and finished upper-level accommodation.

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Renovated Gas Station
Renovated Gas Station

8196 State Route 121 S, Mayfield, KY 42066

$690,000
3,000 sqft

Operating gas station with a 2023 canopy and pump renovation, plus inventory included in the sale.

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Remodeled Live-Work Property
Remodeled Live-Work Property

304 W Walnut St, Mayfield, KY 42066

$874,000
2,000 sqft

Multiple buildings combine residential, office, loft, mechanic, and wash-bay areas.

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Remodeled Mixed-Use Property with Auto Shop
Remodeled Mixed-Use Property with Auto Shop

304 W Walnut Street, Mayfield, KY 42066

$874,000
2,000 sqft 0.13 AC lot

Flexible commercial compound combining office, live-work, automotive, parking, and expansion components.

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Versatile Retail Building
Versatile Retail Building

929 Paris Road lot: 3 & 4, Mayfield, KY 42066

$279,000
2,714 sqft 0.21 AC lot

C-zoned commercial building with central air, forced-air heating, and public sewer.

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Flex Space with Office and Warehouse
Flex Space with Office and Warehouse

900 S Commonwealth Drive, Mayfield, KY 42066

$1,175,000
3,596 sqft 1.90 AC lot

Vacant commercial facility combines finished office areas with high-ceiling flex and warehouse space under one roof.

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Restaurant Property with Appliances
Restaurant Property with Appliances

1023 W Broadway, Mayfield, KY 42066

$245,000
18,399 sqft 0.42 AC lot

Restaurant property includes refrigerators and stoves that will remain with the sale.

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Steel Warehouse with Office Space
Steel Warehouse with Office Space

280 Luisa Ln, Mayfield, KY 42066

$539,000
13,922 sqft

All-steel warehouse on 3.24 fenced acres with three roll-up doors, office/operations space, and new 2025 HVAC.

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Brick Office Unit
Brick Office Unit

419 S 9th Street, Mayfield, KY 42066

$137,500
1,271 sqft 0.12 AC lot

Compact commercial workspace with central air, natural gas heat, and on-site parking in Mayfield.

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Gas Station with New Canopy
Gas Station with New Canopy

8196 State Route 121 S, Mayfield, KY 42066

$690,000
3,000 sqft

Renovated gas station with updated canopy, pump, and inventory included for continued operation.

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Operating Grocery and Convenience Store
Operating Grocery and Convenience Store

620 E Broadway, Mayfield, KY 42066

$550,000
3,752 sqft

Operating grocery and convenience business with inventory and ongoing sales.

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Retail Building for Office or Service Use
Retail Building for Office or Service Use

929 Paris Rd, Mayfield, KY 42066

$279,000
2,714 sqft

Commercial property supports retail, office, and professional-service applications.

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Conventional Restaurant Property
Conventional Restaurant Property

1023 W Broadway, Mayfield, KY 42066

$245,000
18,399 sqft

Refrigerators and stoves remain with the property.

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Commercial Land with Interstate Exposure
Commercial Land with Interstate Exposure

297 Treeland Drive, Mayfield, KY 42066

$1,000,000
14.00 AC lot

Fenced commercial land offers public water and prominent exposure near established travel-center amenities.

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Dual-Frontage Commercial Land
Dual-Frontage Commercial Land

W James Street, Mayfield, KY 42066

$120,000
2.83 AC lot

The parcel carries B-1 zoning and has public water and natural gas available.

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Commercial Land Near Retail
Commercial Land Near Retail

1511 Cuba Road, Mayfield, KY 42066

$425,000
9.56 AC lot

Commercial land near Walmart, retailers, and restaurants with future Cuba Road widening plans.

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Commercial Land Parcel
Commercial Land Parcel

1511 Cuba RD, Mayfield, KY 42066

$425,000
9.56 AC lot

Commercial land with public water and natural gas availability.

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Two-Story Medical Office Building
Two-Story Medical Office Building

1002 Cuba Rd., Mayfield, KY 42066

$895,000

Updated two-level facility with reception, multiple work areas, restrooms, and a kitchenette.

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Mayfield, KY Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Mayfield, KY with 3 listings featured on our commercial real estate exchange. The current inventory includes 13,500 square feet of properties with an estimated lease value of $16.

Estimated lease rates for Commercial real estate in Mayfield, KY begin at $4 SF/Yr, with an average of $8 SF/Yr and extend to $12 SF/Yr.
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