Mayfield, KY Commercial Real Estate for Lease

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Industrial Warehouse with Office Space
Updated: Jan 11
Industrial Warehouse with Office Space

280 Luisa Lane, Mayfield, KY 42066

$4,000/Mo
12,000 sqft
All‑steel industrial warehouse on 3.24 fenced acres built in 1991, less than 1 mile from I‑69 and just off US Hwy 121
Signage facing Hwy 121 directly across from Graves County High School
Building has three roll‑up garage doors for efficient loading and logistics
Power services include two 200‑amp services and one 100‑amp service, plus natural gas; water available and public sewer
New HVAC system installed in 2025; cooling includes electric central air
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Office or Retail Suite
Updated: Sep 12, 2025
Office or Retail Suite

1522 Cuba Road, Mayfield, KY 42066

$1,500/Mo
1,500 sqft
1,500 SF commercial space for lease for offices or retail
Currently set up with four offices and a large reception area
Heating: natural gas; cooling: central air
Year built: 1992
Suite is the first unit where Duncans Pharmacy is located behind Wal Mart
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Office and Retail Suite
Office and Retail Suite

1522 Cuba Rd, Mayfield, KY 42066

$1,500/Mo

Flexible suite with multiple offices and a large reception area at a retail location near Walmart.

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Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 3 Active listings in Mayfield, KY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 42 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

NNN Dollar General Store
NNN Dollar General Store

2675 Main Street, Benton, KY 42025

$1,227,876 SF/Yr
9,026 sqft

Single-tenant Dollar General property offered on a NNN lease with no landlord responsibilities.

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Retail and Office Space for Lease
Retail and Office Space for Lease

815 N 12th Street, Murray, KY 42071

$4,400/Mo

4,000+/- square foot space directly in front of Walmart SuperCenter, suitable for retail or professional office use.

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Commercial Outparcel Land Sites
Commercial Outparcel Land Sites

2602 Main St, Benton, KY 42025

Contact for pricing

Two commercial outparcel sites are available at Benton Shopping Center along US Highway 641 in Benton, KY.

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Retail Space at Bee Creek Centre
Retail Space at Bee Creek Centre

1300 KY-121, Murray, KY 42071

$32 SF/Yr
20,000 sqft

Leasing retail storefronts at Bee Creek Centre, including endcap space with drive-thru.

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Similar Spaces for Sale in Mayfield, KY

Consider Similar Space for Sale. We found 42 Spaces matching your search parameters.

Updated Office Building with Reception
Updated Office Building with Reception

1002 Cuba Road, Mayfield, KY 42066

$845,000
8,444 sqft 0.36 AC lot

Updated two-story office building with a front reception area, multiple workspaces, and several restrooms plus upstairs kitchenette.

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Single-Owner Industrial Warehouse
Single-Owner Industrial Warehouse

280 Luisa Lane, Mayfield, KY 42066

$539,000
13,922 sqft 3.24 AC lot

All-steel warehouse on fenced acreage with three roll-up doors, offices, and an enclosed upstairs loft/work area.

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Renovated Gas Station and Canopy
Renovated Gas Station and Canopy

8196 State Route 121 S, Mayfield, KY 42066

$690,000
3,000 sqft

Renovated in 2023 with a new canopy and pumps, offered for sale with an option to lease.

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Industrial Warehouse and Office Buildings
Industrial Warehouse and Office Buildings

31 E Vaughn Road, Mayfield, KY 42066

$700,000
18,867 sqft 11.27 AC lot

Two-building property features mostly concrete-floor industrial space plus a small office component with ample parking off HWY 45.

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Commercial Live-Work Property
Commercial Live-Work Property

304 W Walnut Street, Mayfield, KY 42066

$874,000
2,000 sqft 0.13 AC lot

2022 remodeled live-work building with office area, overhead doors, and wash bay plus adjacent gravel parking for expansion.

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Restaurant Property with Appliances
Restaurant Property with Appliances

1023 W Broadway, Mayfield, KY 42066

$245,000
18,399 sqft 0.42 AC lot

Restaurant property for sale with key appliances staying, including refrigerators and stoves.

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Commercial Development Land with Interstate Visibility
Commercial Development Land with Interstate Visibility

297 Treeland Drive, Mayfield, KY 42066

$1,000,000
14.00 AC lot

Commercial land tract with visibility from I-69 and Highway 45 North near a travel center and hospitality developments.

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Zoned Commercial Development Land
Zoned Commercial Development Land

W James Street, Mayfield, KY 42066

$120,000
2.83 AC lot

Vacant commercial land with frontage on W James Street and N 11th Street, zoned B-1 for development.

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Steel Warehouse with Office Space
Steel Warehouse with Office Space

280 Luisa Lane, Mayfield, KY 42066

Contact for pricing
14,000 sqft

All-steel warehouse on 3.24 fenced acres with three roll-up doors, office/operations space, and new 2025 HVAC.

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High-Traffic Commercial Development Land
High-Traffic Commercial Development Land

1511 Cuba RD, Mayfield, KY 42066

$425,000
9.56 AC lot

Multi-acre tract near major retail and dining, with planned road widening that can support future commercial development in Mayfield.

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Development Land with Road Widening
Development Land with Road Widening

1511 Cuba Road, Mayfield, KY 42066

$425,000
9.56 AC lot

9.56 acres in Mayfield, KY, noted as near Walmart and other retailers, with remarks citing planned road widening.

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Three-Building Industrial Flex Campus
Three-Building Industrial Flex Campus

224 KY Fab Drive, Mayfield, KY 42066

$950,000

Three-building industrial flex property with existing office space and large warehouse area for contractor and distribution operations.

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Updated Multi-Use Office and Medical Building
Updated Multi-Use Office and Medical Building

1002 Cuba Rd., Mayfield, KY 42066

$895,000

Updated two-level building with reception, multiple restrooms, and abundant parking in a high-visibility Mayfield area.

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Industrial Property with Office Space
Industrial Property with Office Space

31 E Vaughn Rd, Mayfield, KY 42066

$700,000

Two-building industrial offering with concrete-floor warehouse space, an office component, and ample parking near Hwy 45.

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Renovated Gas Station and Convenience Store
Renovated Gas Station and Convenience Store

8196 State Route 121 S, Mayfield, KY 42066

$690,000

Renovated 2023 gas station with new canopy and pumps, offered for sale with possible lease option.

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Established Convenience Store Business
Established Convenience Store Business

620 East Broadway, Mayfield, KY 42066

$550,000

Operating convenience store business available in Mayfield, Kentucky, with inventory and sales continuing through a smooth handoff.

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C-1 Industrial Property
C-1 Industrial Property

1179 U.S. 45, Mayfield, KY 42066

$900,000
14,560 sqft 3.42 AC lot

C-1 zoned industrial property with a 14,560 sq ft building on 3.42 acres in Mayfield, KY.

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Flex Property with Roll-Up Doors
Flex Property with Roll-Up Doors

900 S Commonwealth Drive, Mayfield, KY 42066

$1,175,000

Multi-purpose facility combines professional office space with high-ceiling warehouse storage and three roll-up doors.

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Warehouse with Office and Car Lift
Warehouse with Office and Car Lift

2525 Jimtown Road, Mayfield, KY 42066

$249,900

A versatile warehouse with office space, restroom, and a car lift on 2.91 acres of expansion-ready land.

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Two-Building Restaurant Property
Two-Building Restaurant Property

Brookhaven, Mayfield, KY 42066

$199,000

Restaurant-oriented property includes two detached buildings, with a pending survey to separate from Popeye’s.

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Live-Work and Flex Property
Live-Work and Flex Property

304, 306, 314 W Walnut St, Mayfield, KY 42066

$874,000

2022 remodeled live-work and flex buildings with overhead doors, wash bay, and multiple expansion parking areas.

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Mayfield, KY Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Mayfield, KY with 3 listings featured on our commercial real estate exchange. The current inventory includes 13,500 square feet of properties with an estimated lease value of $16 SF/Yr.

Estimated lease rates for Commercial real estate in Mayfield, KY begin at $4 SF/Yr, with an average of $8 SF/Yr and extend to $12 SF/Yr.
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