Advertise
    Location, space use, price

    Mayfield, KY Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Hickory, KY Sedalia, KY Murray, KY Benton, KY Paducah, KY
    Fenced Flex Space with Loading Doors
    Updated: Jan 11
    Fenced Flex Space with Loading Doors

    280 Luisa Lane, Mayfield, KY 42066

    $4,000/Mo
    12,000 sqft 3.24 AC lot
    12,000 square feet on 3.24 fenced acres
    Less than one mile from I‑69 and just off US Hwy 121
    Three roll‑up garage doors for loading and logistics
    Two 200‑amp power services plus one 100‑amp service
    Enclosed upstairs loft/work area of approximately 2,560 square feet
    View details
    Retail Suite with Office Layout
    Updated: Sep 12, 2025
    Retail Suite with Office Layout

    1522 Cuba Road, Mayfield, KY 42066

    $1,500/Mo
    1,500 sqft 0.44 AC lot
    1,500 SF commercial suite available for lease
    Four offices plus a large reception area
    Suitable for office or retail use
    B‑1 zoning
    Natural gas heating and central air
    View details
    Based on your search, we've compiled 39 Potential Opportunities for your consideration. Besides 2 Active listings in Mayfield, KY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 33 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Building with Six Offices
    Office Building with Six Offices

    6155 Kentucky 1241, Hickory, KY 42051

    $1,700/Mo
    2,558 sqft 0.50 AC lot

    A reception area, meeting space, and paved parking support the building’s current office configuration.

    View details
    Industrial Warehouse with Dock Doors
    Industrial Warehouse with Dock Doors

    150 Remington Way, Hickory, KY 42051

    Contact for pricing
    150,000 sqft

    Completed shell space provides high clearances, dock access, and ample parking for industrial operations.

    View details
    Flex Building With Pull-Through Access
    Flex Building With Pull-Through Access

    1057 State Route 381, Sedalia, KY 42079

    $2,000/Mo

    Open, vacant space with power, heat, a bathroom, and multiple sliding-door entrances.

    View details
    Vacant Flex Space with Pull-Through Access
    Vacant Flex Space with Pull-Through Access

    1057 KY-381, Sedalia, KY 42079

    $2,000/Mo
    4,480 sqft 0.50 AC lot

    Open, vacant commercial space includes utility service, heating, a bathroom, and multiple large sliding-door entrances.

    View details

    Similar Spaces for Sale in Mayfield, KY

    Consider Similar Space for Sale. We found 33 Spaces matching your search parameters.

    Updated Medical Office Building
    Updated Medical Office Building

    1002 Cuba Road, Mayfield, KY 42066

    $795,000
    8,444 sqft 0.36 AC lot

    Flexible commercial layout with reception, multiple work areas, upstairs finished space, and open parking.

    View details
    Convenience Store Property
    Convenience Store Property

    1425 W Broadway, Mayfield, KY 42066

    $225,000
    1,107 sqft 1.10 AC lot

    The B-1-zoned property includes a compact building with central air conditioning and forced-air heating.

    View details
    Medical Office Building with Reception
    Medical Office Building with Reception

    1002 Cuba Rd, Mayfield, KY 42066

    $795,000
    8,444 sqft

    Updated interior includes multiple work areas, reception space, restrooms, and finished upper-level accommodation.

    View details
    Flex Space with Office
    Flex Space with Office

    900 S Commonwealth Dr, Mayfield, KY 42066

    $1,175,000
    3,596 sqft 1.90 AC lot

    Commercial facility combines finished office areas with warehouse functionality and roll-up access under one roof.

    View details
    Renovated Gas Station
    Renovated Gas Station

    8196 State Route 121 S, Mayfield, KY 42066

    $690,000
    3,000 sqft

    Operating gas station with a 2023 canopy and pump renovation, plus inventory included in the sale.

    View details
    Flex Space with Office and Warehouse
    Flex Space with Office and Warehouse

    900 S Commonwealth Drive, Mayfield, KY 42066

    $1,175,000
    3,596 sqft 1.90 AC lot

    Vacant commercial facility combines finished office areas with high-ceiling flex and warehouse space under one roof.

    View details
    Restaurant Property with Appliances
    Restaurant Property with Appliances

    1023 W Broadway, Mayfield, KY 42066

    $245,000
    18,399 sqft 0.42 AC lot

    Restaurant property includes refrigerators and stoves that will remain with the sale.

    View details
    Gas Station with New Canopy
    Gas Station with New Canopy

    8196 State Route 121 S, Mayfield, KY 42066

    $690,000
    3,000 sqft

    Renovated gas station with updated canopy, pump, and inventory included for continued operation.

    View details
    Remodeled Live-Work Property
    Remodeled Live-Work Property

    304 W Walnut St, Mayfield, KY 42066

    $747,000
    2,000 sqft

    Multiple buildings combine residential, office, loft, mechanic, and wash-bay areas.

    View details
    Operating Grocery and Convenience Store
    Operating Grocery and Convenience Store

    620 E Broadway, Mayfield, KY 42066

    $550,000
    3,752 sqft

    Operating grocery and convenience business with inventory and ongoing sales.

    View details
    Specialty Property with Chapel Use
    Specialty Property with Chapel Use

    420 E Water Street, Mayfield, KY 42066

    $175,000
    2,916 sqft 0.23 AC lot

    The 2,916-square-foot building includes equipment and has R-2 zoning.

    View details
    Convenience Store Building
    Convenience Store Building

    1425 W Broadway, Mayfield, KY 42066

    $225,000
    1,107 sqft

    The building has a public restroom, a separate office restroom, and a wheelchair ramp.

    View details
    Mixed-Use Live-Work Property
    Mixed-Use Live-Work Property

    304 W Walnut Street, Mayfield, KY 42066

    $747,000
    2,000 sqft 0.13 AC lot

    Remodeled commercial property combines residential space, offices, automotive functionality, and additional gravel parking areas.

    View details
    Conventional Restaurant Property
    Conventional Restaurant Property

    1023 W Broadway, Mayfield, KY 42066

    $245,000
    18,399 sqft

    Refrigerators and stoves remain with the property.

    View details
    Chapel Building with Equipment
    Chapel Building with Equipment

    420 E Water St, Mayfield, KY 42066

    $175,000
    2,916 sqft

    The existing memorial chapel retains most of its equipment, with the building located near downtown Mayfield.

    View details
    Freestanding Retail Building
    Freestanding Retail Building

    1018 Paris Road, Mayfield, KY 42066

    Contact for pricing
    3,100 sqft 0.81 AC lot

    Prominent building signage and multiple access points serve the freestanding retail property.

    View details
    Brick Office Unit
    Brick Office Unit

    419 S 9th Street, Mayfield, KY 42066

    $137,500
    1,271 sqft 0.12 AC lot

    Compact commercial workspace with central air, natural gas heat, and on-site parking in Mayfield.

    View details
    Commercial Land
    Commercial Land

    1511 Cuba Road, Mayfield, KY 42066

    $425,000
    416,433 sqft

    The site is near Walmart, other retailers, and restaurants.

    View details
    C-1 Industrial Property
    C-1 Industrial Property

    1179 U.S. 45, Mayfield, KY 42066

    $900,000
    14,560 sqft 3.42 AC lot

    C-1 zoned industrial property with a 14,560 sq ft building on 3.42 acres in Mayfield, KY.

    View details
    Commercial Land Near Retail
    Commercial Land Near Retail

    1511 Cuba Road, Mayfield, KY 42066

    $425,000
    9.56 AC lot

    Commercial land near Walmart, retailers, and restaurants with future Cuba Road widening plans.

    View details
    Three-Building Flex Space Property
    Three-Building Flex Space Property

    224 Ky Fab Road, Mayfield, KY 42066

    $875,000
    24,000 sqft 4.00 AC lot

    Three buildings combine office and warehouse areas within a flexible commercial property zoned C.

    View details
    B-1 Commercial Land
    B-1 Commercial Land

    35 Parkway Drive, Mayfield, KY 42066

    $39,900
    0.66 AC lot

    Commercial lot in Thornapple Subdivision with B-1 zoning and access near Hwy 80 and I69.

    View details

    Mayfield, KY Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Mayfield, KY with 2 listings featured on our commercial real estate exchange. The current inventory includes 13,500 square feet of properties with an estimated lease value of $16.

    Estimated lease rates for Commercial real estate in Mayfield, KY begin at $4 SF/Yr, with an average of $8 SF/Yr and extend to $12 SF/Yr.
    Mayfield, KY CRE market trends — vacancy, lease rates and price per SF, updated monthly
    List
    Map

    Browse Commercial real estate for Lease Near Mayfield, KY

    Popular Searches in Mayfield, KY

    Most Searched ZIP Codes in Mayfield, KY

    • 42066

    Featured Mayfield Real Estate Agencies

    Realmo connects you with licensed Mayfield CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Harris Real Estate & Auction
    3855 State Route 45 North Mayfield, KY 42066
    Phone: (270) 247-3253
    www.harrisauctions.com
    Trifecta Real Estate Services
    PO Box 447 Mayfield, KY 42066
    Phone: (270) 247-2734
    www.trifectares.com
    Barger Realty of Kentucky Inc
    328 South Sixth Street Mayfield, KY 42066
    Phone: (270) 247-2421
    www.barger-realty.com
    Why this one?
    Saved

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!