Weeki Wachee, FL Commercial Real Estate for Lease

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Prime Medical Office Space Available
Updated: Nov 25, 2025
Prime Medical Office Space Available

15451 Commercial Way, Weeki Wachee, FL

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21,000 sqft
Direct approved access to/from US‑19, saving the developer approximately $880,000.
Located in one of Florida’s fastest‑growing markets with 18,000 new rooftops with high household income plus new commercial development.
High physician demand projected in multiple specialties over the next five years.
Permit(s) transferable to Buyer (In permitting).
2.0 MOL acres with 400’ frontage on US‑19 and high traffic count estimated ±92,140 AADT.
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Retail Space in Weeki Wachee
Updated: Feb 6, 2024
Retail Space in Weeki Wachee

9595 Commercial Way (U.S. 19), Weeki Wachee, FL 34613

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Anchored by Publix, a major grocery store chain.
Located in Weeki Wachee, FL, just 43 minutes north of Tampa.
Offers retail space for lease.
Includes Anytime Fitness.
Includes Dunkin' Donuts.
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Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 2 Active listings in Weeki Wachee, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 30 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Flexible Commercial Retail/Office Space
Flexible Commercial Retail/Office Space

12150 Cortez Boulevard, Brooksville, FL 34613

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2,000 sqft

Lease a versatile commercial suite on a highly traveled corridor with convenient access and ample on-site parking.

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Office Suite with Reception Area
Office Suite with Reception Area

6149 Deltona Boulevard, Spring Hill, FL 34606

$1,250/Mo

Office suite offers a reception area, multiple private offices, and two bathrooms with water and trash included.

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Multi-Tenant Office Suite
Multi-Tenant Office Suite

6149-6149 Deltona Blvd, Spring Hill, FL 34606

$1,250/Mo

Former insurance office suite with reception, multiple closed offices, and two bathrooms, with water and trash included.

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Brooksville Industrial Park Flex Space
Brooksville Industrial Park Flex Space

13400 Chambord St, Brooksville, FL 34613

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Premier industrial park with flexible lease terms and various unit sizes.

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Similar Spaces for Sale in Weeki Wachee, FL

Consider Similar Space for Sale. We found 30 Spaces matching your search parameters.

Waterfront Multi-Use Marina Property
Waterfront Multi-Use Marina Property

7154 SHOAL LINE Boulevard, Weeki Wachee, FL 34607

$3,500,000
0.71 AC lot

Multi-use waterfront property with direct Weeki Wachee River access, retail store, marine service area, and on-site fuel sales.

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Zoned Agricultural Land Parcel
Zoned Agricultural Land Parcel

12351 Hooker Road, Weeki Wachee, FL 34614

$250,000
2.50 AC lot

Approximately 2.5 acres of AG-zoned land with a well and electricity already in place.

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Prime Land in Growing Florida
Prime Land in Growing Florida

HOOKER Rd, Weeki Wachee, FL 34614

$1,550,000
0.46 AC lot

20,000 SF parcel ideal for development in Weeki Wachee.

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Cleared Commercial Lot
Cleared Commercial Lot

10260 YALE Ave, Weeki Wachee, FL 34613

$525,000

Cleared, level commercial lot on Yale and Cortez Blvd., with access to US 19 about 1.3 miles away.

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Commercial Land on Commercial Way
Commercial Land on Commercial Way

Commercial Way, Weeki Wachee, FL 34614

$42,500
0.60 AC lot

Highly visible 0.6 acre lot in growing Weeki Wachee.

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Weeki Wachee Investment Land
Weeki Wachee Investment Land

9468 MARENGO Street, Weeki Wachee, FL 34613

$164,000
1.72 AC lot

1.72 acres near Weeki Wachee Springs State Park.

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Commercial Land on US 19
Commercial Land on US 19

7092 Commercial Way, Weeki Wachee, FL 34613

$115,000
0.31 AC lot

Highly visible 0.31 acre lot on US 19.

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Commercial Land on US 19
Commercial Land on US 19

7088 commercial Way, Weeki Wachee, FL 34613

$115,000
0.31 AC lot

0.31 acre lot on US 19 in Weeki Wachee, FL

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Vacant Lot in Hernando County
Vacant Lot in Hernando County

14476 Canvasback Rd, Weeki Wachee, FL 34614

$49,999
0.55 AC lot

Vacant lot with 23,825 sqft in North Weeki Wachee.

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Weeki Wachee Investment Opportunity
Weeki Wachee Investment Opportunity

9468 Marengo Street, Weeki Wachee, FL 34613

$164,000
1.72 AC lot

1.72-acre lot near Weeki Wachee Springs State Park.

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Agricultural Land Near Royal Highlands
Agricultural Land Near Royal Highlands

00 LELANI Dr, Weeki Wachee, FL 34614

$89,900
1.60 AC lot

1.60-acre agricultural-zoned homesite in Leisure Retreats, Weeki Wachee.

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Weeki Wachee Land For Sale
Weeki Wachee Land For Sale

Nakoma Way, Weeki Wachee, FL 34613

$1,399,000
13.50 AC lot

13.5 acres in Weeki Wachee, near US 19.

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Cleared Corner Commercial Lot
Cleared Corner Commercial Lot

10288 Lot 8 YALE Avenue, Weeki Wachee, FL 34613

$1,100,000
0.98 AC lot

Nearly one-acre corner lot is cleared and shovel ready with frontage along Nightwalker Rd, Cortez Blvd, and Yale Ave.

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Cleared Level Commercial Lot
Cleared Level Commercial Lot

10260 YALE Avenue, Weeki Wachee, FL 34613

$525,000
0.59 AC lot

Cleared, level commercial lot with frontage on Yale Avenue and Cortez Blvd.

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Shovel-Ready Corner Development Land
Shovel-Ready Corner Development Land

8 Yale Avenue, Weeki Wachee, FL 34613

$1,100,000
42,866 sqft 0.98 AC lot

Cleared corner lot with frontage on Nightwalker Rd, Cortez Blvd, and Yale Ave, plus an electric billboard.

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Cleared Corner Lot in Florida
Cleared Corner Lot in Florida

10288 Lot 8 Yale Avenue, Weeki Wachee, FL 34613

$1,100,000
0.98 AC lot

Corner lot, cleared and ready for development in Weeki Wachee.

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Commercial Lot in Weeki Wachee
Commercial Lot in Weeki Wachee

10260 Yale Avenue, Weeki Wachee, FL 34613

$525,000
0.59 AC lot

Cleared, level commercial lot located on Yale and Cortez.

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Cleared Land on Cortez Blvd
Cleared Land on Cortez Blvd

10270 Yale Avenue, Weeki Wachee, FL 34613

$525,000
0.57 AC lot

Cleared 0.57 acre lot on Cortez Blvd and Yale Ave.

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Highway-Facing Commercial Land Package
Highway-Facing Commercial Land Package

10270 Atlanta Ave, Weeki Wachee, FL 34614

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Commercial land package with seven lots totaling 5.7+ acres on a busy highway corridor.

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Cleared Corner Lot For Sale
Cleared Corner Lot For Sale

10201 YALE Avenue, Weeki Wachee, FL 34613

$525,000
0.81 AC lot

0.80 acre corner lot, cleared and level, near US 19.

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Cleared Land on Cortez Blvd
Cleared Land on Cortez Blvd

10270 YALE Avenue, Weeki Wachee, FL 34613

$525,000
0.57 AC lot

Cleared, shovel-ready land with frontage on Cortez Boulevard.

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Cleared Corner Lot Near US-19
Cleared Corner Lot Near US-19

10201 Yale Avenue, Weeki Wachee, FL 34613

$525,000
0.81 AC lot

0.81 acre cleared, level corner lot near US-19.

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Weeki Wachee, FL Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Weeki Wachee, FL with 2 listings featured on our commercial real estate exchange. The current inventory includes 21,000 square feet of properties.
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