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    Desoto County, FL Commercial Real Estate for Lease

    9 results
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    Arcadia Retail/Warehouse Opportunity
    $8 SF/Yr
    15,555 SF

    Arcadia Retail/Warehouse Opportunity

    14 W HICKORY STREET, Arcadia, FL 34266

    15,555 SF building ideal for retail, warehouse, or service operations.

    • Prime visibility at a signalized corner in downtown Arcadia.
    • High traffic count: Over 22,000 vehicles pass daily.
    • Flexible open floorplan suitable for retail, warehouse, or service operations.
    • Rear bay door with dock‑high loading.
    • 10+ on‑site parking spaces.
    Updated: Oct 8, 2025
    View details
    Arcadia Office Space For Rent
    $22 SF/Yr
    10,330 SF

    Arcadia Office Space For Rent

    920 N MILLS AVENUE, Arcadia, FL 34266

    Office space in growing area, ideal for medical or professional.

    • Ideal location across from Desoto Memorial Hospital, suitable for medical, professional, or business offices.
    • Zoned RPB, allowing for medical, professional, business, and even residential use.
    • Located in an area with exploding population growth and high demand for professional and business space.
    • Ample parking available for 20 cars.
    • Features a brand new metal roof.
    Updated: May 22, 2025
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    Arcadia Warehouse Space Available
    $5,000 /Mo
    25,143 SF

    Arcadia Warehouse Space Available

    25,000+ sq ft warehouse in DeSoto Business Park.

    0 SE HIGHWAY 31, Arcadia, FL 34266
    View details
    Arcadia Retail/Office Space For Rent
    $25 SF/Yr

    Arcadia Retail/Office Space For Rent

    Retail or office space with excellent exposure on Oak Street.

    921 East Oak Street, Arcadia, FL 34266
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    Arcadia Retail/Office/Warehouse Space
    Contact for pricing

    Arcadia Retail/Office/Warehouse Space

    Located in the heart of Arcadia, perfect for retail or office.

    1401 Martin Luther King Jr Street SW, Arcadia, FL 34266
    View details
    Retail Property in Arcadia, Florida
    $900 /Mo
    12,975 SF

    Retail Property in Arcadia, Florida

    Retail property with great potential for business growth.

    1401 SW MARTIN LUTHER KING JR STREET, Arcadia, FL 34266
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    Arcadia Retail Property For Sale
    Contact for pricing
    3,721 SF

    Arcadia Retail Property For Sale

    Retail property available for purchase in Arcadia, Florida.

    9836 SW County Road 761, Arcadia, FL
    View details
    Retail Space in Nocatee Center
    $45 SF/Yr
    1,390 SF

    Retail Space in Nocatee Center

    Retail space available in a highly anticipated Nocatee shopping center.

    75 Irondale Rd, Nocatee, FL
    View details
    Arcadia Plaza Retail Space
    Contact for pricing
    1,200 SF

    Arcadia Plaza Retail Space

    Retail spaces available at Arcadia Plaza in Arcadia, Florida.

    1703-1737 E Oak St, Arcadia, FL
    View details
    Based on your search, we've compiled 67 Potential Opportunities for your consideration. Besides 9 Active listings in Desoto County, FL, we suggest exploring alternatives. Similar 54 Properties for Sales.

    Explore Similar Spaces for Sale in Desoto County, FL

    Consider Similar Space for Sale. We found 54 Spaces matching your search parameters.

    Commercial Property on Highway 17
    $975,000
    7,034 SF

    Commercial Property on Highway 17

    2.93-acre commercial property suitable for retail, office, or educational use.

    5241 SW HIGHWAY 17, Arcadia, FL 34266
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    8.96 Acres in ARCADIA, FL
    $450,000
    8.96 Acres

    8.96 Acres in ARCADIA, FL

    8.96-acre corner lot suitable for custom home or ranch.

    WASHINGTON STREET, Arcadia, FL 34266
    View details
    Ice Cream Shop Business Opportunity
    $99,000

    Ice Cream Shop Business Opportunity

    Thriving ice cream shop business for sale in downtown Arcadia.

    203 W OAK STREET, Arcadia, FL 34266
    View details
    20 Acres Irrigated Agricultural Land
    $495,000
    20.00 Acres

    20 Acres Irrigated Agricultural Land

    20 acres of irrigated land with fruit trees and infrastructure.

    NE HWY 70, Arcadia, FL 34266
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    30 Acres of Florida Woodland
    $575,000
    30.00 Acres

    30 Acres of Florida Woodland

    30 acres of woodland near Hwy 70 and Hwy 31.

    SE HWY 31, Arcadia, FL 34266
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    Arcadia 5-Acre Agricultural Land Parcel
    $175,000
    5.00 Acres

    Arcadia 5-Acre Agricultural Land Parcel

    5 acres in Arcadia, zoned A-5 agricultural, suitable for various uses.

    1775 NE CROSS AVENUE, Arcadia, FL 34266
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    Arcadia Commercial Land For Sale
    $250,000
    0.60 Acres

    Arcadia Commercial Land For Sale

    Corner lot on Highway 17, ideal for commercial development.

    103 N Brevard Ave, Arcadia, FL 34266
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    Arcadia Land on Highway 17
    Contact for pricing
    0.74 Acres

    Arcadia Land on Highway 17

    Nearly three-quarters of an acre with highway visibility and potential.

    SW HWY 17, Arcadia, FL 34266
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    Arcadia Mixed-Use Development Opportunity
    $4,500,000
    136,190 SF

    Arcadia Mixed-Use Development Opportunity

    73+ acres with Hwy 31 frontage, near Fort Myers.

    6000 SE HWY 31, Arcadia, FL 34266
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    40-Acre Producing Citrus Grove
    $719,480
    40.00 Acres

    40-Acre Producing Citrus Grove

    Producing 40-acre citrus grove in South DeSoto County.

    SE HWY 31, Arcadia, FL 34266
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    Arcadia Medical/Professional Office For Sale
    $299,900
    1,968 SF

    Arcadia Medical/Professional Office For Sale

    Well-located medical/professional office in Arcadia's medical district.

    303 E GIBSON STREET, Arcadia, FL 34266
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    Arcadia Vacant Land with Building
    $289,000
    3.16 Acres

    Arcadia Vacant Land with Building

    Vacant land with metal building in Joshua Creek neighborhood.

    3063 SE CREEKWOOD TERRACE, Arcadia, FL 34266
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    Arcadia Commercial Land on Corner
    $200,000
    0.30 Acres

    Arcadia Commercial Land on Corner

    Prime commercial land on Highway 17 and Hickory corner.

    117 N Brevard, Arcadia, FL 34266
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    Prime Commercial Land in Lake Suzy
    $649,000
    2.48 Acres

    Prime Commercial Land in Lake Suzy

    2.48-acre commercial property with high visibility and accessibility.

    12280 SW County Road 769, Lake Suzy, FL 34269
    View details
    310 Acres on Peace River
    $3,100,000
    310.00 Acres

    310 Acres on Peace River

    Rare Florida property with Peace River frontage and abundant wildlife.

    1061 HARRIS ROAD, Arcadia, FL 34266
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Retail Land For Lease
    Contact for pricing

    Retail Land For Lease

    Retail land available for lease, build-to-suit, or ground lease.

    1401 Price Creek Way, North Port, FL 34288
    View details
    Babcock Ranch Commercial Land Lease
    Contact for pricing

    Babcock Ranch Commercial Land Lease

    Commercial land available for lease in Babcock Ranch, Florida.

    Punta Gorda, FL 33982
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    Port Charlotte Outparcel Near I-75
    Contact for pricing

    Port Charlotte Outparcel Near I-75

    Outparcel near I-75 and a Publix-anchored shopping center.

    24060 Beatrix Blvd, Port Charlotte, FL
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    Prime Commercial Land Available
    Contact for pricing
    1,306,800 SF

    Prime Commercial Land Available

    Commercial outparcels and tracts for ground lease in North Port.

    1100 N Toledo Blade Blvd, North Port, FL 34288
    View details

    Desoto County, FL Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Desoto County, FL with 9 listings featured on our commercial real estate exchange. The current inventory includes 2,787,970,680 square feet of properties with an estimated lease value of $33 SF/Yr.

    Estimated lease rates for Commercial real estate in Desoto County, FL begin at $0.83 SF/Yr, with an average of $8 SF/Yr and extend to $22 SF/Yr.
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