Middletown, DE Commercial Real Estate for Lease

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47 properties
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Retail Space Near Food Lion
Updated: Nov 24, 2025
Retail Space Near Food Lion

488 Middletown Warwick Rd, Middletown, DE

$30 SF/Yr
3,300 sqft
Located in a high‑traffic commercial district with excellent visibility and easy access.
Anchored by major retailers including Food Lion, McDonalds, Chase Bank, Panera Bread and IHOP.
Benefits from a growing economic market and surrounding major retail concentration.
3,300 SF of inline retail space available.
High daytime population numbers.
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Proposed Flex Building For Lease
Updated: Nov 10, 2025
Proposed Flex Building For Lease

410 Diamond State Blvd, Middletown, DE

$14 SF/Yr
2,275 sqft
New flex building with delivery in Q1 2024.
Flexible unit sizes ranging from 2,065 SF to 13,440 SF.
Standard unit includes a fully conditioned private office.
Each unit has an ADA compliant restroom.
Features include LED warehouse lighting and a gas‑fired suspended heater.
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Middletown Flex Space For Lease
Middletown Flex Space For Lease

108 Patriot Dr, Middletown, DE, Middletown, DE 19709

$14 SF/Yr
24,892 sqft

3,137 SF flex space near Route 1 and 301.

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Office Space with Garage
Office Space with Garage

5193 SUMMIT BRIDGE Rd, Middletown, DE 19709

$3,500/Mo

Office spaces and garage available for rent.

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Middletown Industrial Suites Available
Middletown Industrial Suites Available

700 North Broad Street, Middletown, DE 19709

Contact for pricing
87,730 sqft

Industrial suites available for lease in Middletown, Delaware.

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Office Space with 24/7 Access
Office Space with 24/7 Access

651 N BROAD St MAILING ADDRESS, Middletown, DE 19709

$75 SF/Yr

Office space with 24/7 access, kitchen, restrooms, and parking.

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Prime Pad Site For Lease
Prime Pad Site For Lease

111 Sandhill Dr, Middletown, DE 19709

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1 sqft

1.04 acre pad site in Bunker Hill area, Middletown, DE.

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Retail Building in Middletown, DE
Retail Building in Middletown, DE

455 W Main St, Middletown, DE

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14,600 sqft

Freestanding +/- 14,600 SF retail building for lease.

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Retail Space For Lease
Retail Space For Lease

790 Levels Rd, Middletown, DE

$32 SF/Yr
1,755 sqft

Retail spaces available from 1,755 to 12,285 SF.

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Medical Office Suites in Plaza
Medical Office Suites in Plaza

118 Sandhill Dr, Middletown, DE 19709

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Well-kept medical office suites with abundant parking and convenient access to key regional routes.

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Medical Office Suite for Lease
Medical Office Suite for Lease

114 Sandhill Dr, Middletown, DE 19709

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Well-kept medical office suite in a parking-rich complex with quick access to Routes 299 and 301.

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Retail Space in Middletown Corridor
Retail Space in Middletown Corridor

851 Middletown Warwick Rd, Middletown, DE

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1,955 sqft

Prime retail spaces available in high-traffic Middletown location.

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Middletown Manufacturing/Industrial Space Available
Middletown Manufacturing/Industrial Space Available

108 Sleepy Hollow Dr, Middletown, DE

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4,000 sqft

4,000 SF manufacturing/industrial space in Middletown, Delaware for lease.

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Retail Space on Main Street
Retail Space on Main Street

454 E Main St, Middletown, DE

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1,200 sqft

Retail space available for lease on Main Street.

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Retail Space on Main Street
Retail Space on Main Street

460 E Main St, Middletown, DE

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1,600 sqft

Retail space available for rent in Middletown, Delaware.

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Retail Space on Main Street
Retail Space on Main Street

304-340 E Main St, Middletown, DE

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1,600 sqft

Retail space available for rent in Middletown, Delaware.

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Retail Space in Middletown Crossing
Retail Space in Middletown Crossing

362-386 E Main St, Middletown, DE

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4,800 sqft

Retail space available in a busy shopping center.

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Medical Suite Available For Rent
Medical Suite Available For Rent

124 Sleepy Hollow Dr, Middletown, DE

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1,271 sqft

Second floor medical suite with easy access and nearby amenities.

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Middletown Industrial Land for Lease
Middletown Industrial Land for Lease

605 Tower Ln, Middletown, DE 19709

$4,500/Mo
30,000 sqft

2.62 acres of industrial land available for lease.

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Grocery-Anchored Retail Space Available
Grocery-Anchored Retail Space Available

Boyds Corner & Jamison Corner Road, Middletown, DE 19709

Contact for pricing
248,655 sqft

Retail and office spaces for lease in growing residential community.

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Middletown Office/Retail Space Available
Middletown Office/Retail Space Available

651 N BROAD St SUITE 106 , UNIT 106, Middletown, DE 19709

$850/Mo

Office and retail space for rent in Middletown, Delaware.

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Flex Building with Available Unit
Flex Building with Available Unit

410 Diamond State Blvd, Middletown, DE 19709

$14 SF/Yr
13,440 sqft

Flex building with units available for lease in Middletown, DE.

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Commercial Land Near Christiana Care
Commercial Land Near Christiana Care

230 E Hampden Rd, Middletown, DE

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Located near hospital and major retailers in Middletown, Delaware.

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Commercial Land Near Christiana Care
Commercial Land Near Christiana Care

235 E Hampden Rd, Middletown, DE

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Land available for rent near hospital and retail.

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Middletown, DE Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Middletown, DE with 47 listings featured on our commercial real estate exchange. The current inventory includes 78,799 square feet of properties with an estimated lease value of $119.80 SF/Yr.

Estimated lease rates for Commercial real estate in Middletown, DE begin at $1.80 SF/Yr, with an average of $17.11 SF/Yr and extend to $32 SF/Yr.
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