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    Palo Alto, CA Commercial Real Estate for Lease

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    Class A Office Space Available
    Class A Office Space Available

    431 Waverley Street, Palo Alto, CA 94301

    $9.95 SF/Yr
    15,599 sqft

    Prime downtown Palo Alto office space for lease.

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    Creative Tech Space with Patios
    Creative Tech Space with Patios

    541-545 Bryant St, Palo Alto, CA 94301

    Contact for pricing
    2,854 sqft

    Loft-style creative space featuring rooftop patios and modern amenities.

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    Retail Storefront Space
    Retail Storefront Space

    855 El Camino Real, Palo Alto, CA 94301

    Contact for pricing
    919 sqft

    Retail storefront totaling 919 sq. ft., currently occupied by Jamba Juice and available after 12/31/2027.

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    Retail Storefront with Parking
    Retail Storefront with Parking

    2675 El Camino Real, Palo Alto, CA 94306

    Contact for pricing
    2,062 sqft

    2,062 SF retail site with 36 onsite parking spaces and bike parking, positioned along El Camino Real traffic.

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    Palo Alto Flex R&D Space
    Palo Alto Flex R&D Space

    3380 Coyote Hill Rd, Palo Alto, CA 94304

    $7.50 SF/Yr
    42,710 sqft

    Flex R&D space available for sublease in Palo Alto.

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    Class A Office Suites
    Class A Office Suites

    335 Bryant St, Palo Alto, CA 94301

    Contact for pricing
    3,711 sqft

    Elevator-served second and third floor suites with private office build-outs, kitchenettes, and restrooms.

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    Class A Downtown Office Suites
    Class A Downtown Office Suites

    335 Bryant St, Palo Alto, CA 94301

    Contact for pricing
    4,118 sqft

    Elevator-served suites with strong window lines and in-suite kitchenettes and restrooms in a Class A downtown office building.

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    Prime Retail Space on California Avenue
    Prime Retail Space on California Avenue

    490 California Avenue, Palo Alto, CA 94306

    Contact for pricing
    2,780 sqft

    High-visibility retail space in Palo Alto's coveted commercial district.

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    Furnished Second-Floor Office Suite
    Furnished Second-Floor Office Suite

    524 Hamilton Ave, Palo Alto, CA 94301

    Contact for pricing
    3,055 sqft

    Fully furnished second-floor office suite with key-card access, private offices, a large conference room, and an in-suite restroom with shower.

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    Office Space Near Highway Access
    Office Space Near Highway Access

    821 San Antonio Road, Palo Alto, CA 94303

    Contact for pricing
    1,620 sqft

    Centrally located office space with access to Highway 101 and Interstate 280.

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    Full-Service Boutique Hotel
    Full-Service Boutique Hotel

    520 Cowper St, Palo Alto, CA 94301

    Contact for pricing
    7,449 sqft

    Full-service boutique hotel with an on-site signature restaurant component in downtown Palo Alto.

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    Plug-and-Play Office Unit
    Plug-and-Play Office Unit

    Palo Alto, CA 94301

    Contact for pricing
    1,750 sqft

    Configured office suite with meeting rooms, conference rooms, underground parking, and EV charging.

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    Downtown Palo Alto Office Sublease
    Downtown Palo Alto Office Sublease

    Palo Alto, CA 94301

    Contact for pricing
    9,320 sqft

    Class A office space available for sublease in Palo Alto.

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    Office Space with Conference Rooms
    Office Space with Conference Rooms

    505 Hamilton Avenue, Palo Alto, CA 94301

    Contact for pricing
    3,473 sqft

    Updated office space with abundant natural light and a full kitchen.

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    Retail Storefront for Lease
    Retail Storefront for Lease

    855 El Camino Real, Palo Alto, CA 94301

    Contact for pricing
    1,911 sqft

    Retail storefront currently occupied by Jamba Juice, with availability after 12/31/2027.

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    Office Suite with Elevator Access
    Office Suite with Elevator Access

    537 Hamilton Avenue, Palo Alto, CA 94301

    Contact for pricing
    9,242 sqft

    Elevated first-floor office space includes elevator access, floor-to-ceiling glass, and secured designated parking.

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    Lab Office Space with Fume Hoods
    Lab Office Space with Fume Hoods

    2631 Hanover St, Palo Alto, CA 94306

    Contact for pricing
    11,000 sqft

    Climate-controlled lab-to-office suite includes fume hoods, support rooms, shipping and receiving, and plug-and-play offices.

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    Coworking Space
    Coworking Space

    2400 Hanover St, Palo Alto, CA 94304

    Contact for pricing
    38,000 sqft

    Office space is available for lease within a coworking property.

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    Plug-and-Play Office Suite
    Plug-and-Play Office Suite

    400 Hamilton Ave, Palo Alto, CA 94301

    Contact for pricing
    9,320 sqft

    Ground-floor suite with private entrance, board room, collaborative areas, and new LED lighting.

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    Single-Tenant Office Building
    Single-Tenant Office Building

    203 Forest Ave, Palo Alto, CA 94301

    Contact for pricing
    4,228 sqft

    Single-tenant office building with open layout, high ceilings, and skylights, plus a mezzanine workspace and on-site parking.

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    Downtown Palo Alto Retail/Office Space
    Downtown Palo Alto Retail/Office Space

    353 University Ave, Palo Alto, CA 94301

    Contact for pricing
    6,014 sqft 0.14 AC lot

    Prime University Avenue location suitable for retail or office.

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    Palo Alto Lab Space Available
    Palo Alto Lab Space Available

    Palo Alto, CA 94303

    Contact for pricing
    16,447 sqft

    Turn-key lab/office suites with shared utilities for lease.

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    New Class A Retail Space
    New Class A Retail Space

    4115 El Camino Real, Palo Alto, CA 94306

    $18,340/Mo

    New Class A retail space built in 2025 on highly visible El Camino Real, suited for fitness, wellness, or specialty retail.

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    Flex R&D Space with Courtyard
    Flex R&D Space with Courtyard

    4005 Miranda Ave, Palo Alto, CA 94304

    Contact for pricing
    28,582 sqft

    Lease offering includes a courtyard, bike lockers, and EV chargers.

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