For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Retail
1
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Frederick, MD Retail Properties & Spaces for Lease

52 results
List
Map
Downtown Frederick Retail/Restaurant Space
$20 SF/Yr

Downtown Frederick Retail/Restaurant Space

358 W PATRICK Street, Frederick, MD 21701

Shell condition retail or restaurant space in historic downtown Frederick.

  • Prime restaurant or retail location in historic Downtown Frederick
  • 2,279 SF first floor space
  • Great visibility and walkability to downtown amenities
  • Free off‑street parking
  • Zoned DB Downtown Business
Updated: Jan 19
View details
Frederick Commercial Space with Drive-Through
$18 SF/Yr

Frederick Commercial Space with Drive-Through

198 THOMAS JOHNSON Drive unit: 207, Frederick, MD 21701

Versatile commercial space in Frederick, ideal for various businesses.

  • High‑visibility location in Frederick City with heavy traffic flow.
  • Versatile +/- 1,890sf space suitable for various businesses.
  • Benefit from Drive‑through access (formerly a bank).
  • ADA accessibility with main‑level ramp.
  • Large parking lot.
Updated: Nov 9, 2025
View details
Frederick Commercial Space with Drive-Through
$18 SF/Yr

Frederick Commercial Space with Drive-Through

Versatile commercial space in Frederick, ideal for various businesses.

198 THOMAS JOHNSON Drive unit: 205-206, Frederick, MD 21701
View details
Frederick Warehouse Retail Sublease Available
$8 SF/Yr

Frederick Warehouse Retail Sublease Available

4,800 SF warehouse retail sublease in Frederick, Maryland.

622 N MARKET Street, Frederick, MD 21701
View details
Renovated Commercial Property in Urbanna
$3,750 /Mo

Renovated Commercial Property in Urbanna

Completely renovated retail or office space in Urbanna, Maryland.

8832 Urbana Church Rd, Frederick, MD 21704
View details
Downtown Frederick Retail Space Available
$63,685

Downtown Frederick Retail Space Available

Street-level retail space in a prime downtown Frederick location.

244 E Patrick St, Frederick, MD 21701
View details
Retail Space Near I-270
Contact for pricing

Retail Space Near I-270

Retail space in fast-growing Frederick, Maryland near Westview Promenade.

4959-4969 Westview Drive, Frederick, MD 21703
View details
Urbana Pike Retail/Office Space
$3,875 /Mo

Urbana Pike Retail/Office Space

Professional suites off 355 in Urbana, available in 2023.

3535 URBANA Pike unit: 201, Frederick, MD 21704
View details
Retail Space Available For Rent
Contact for pricing
1,540 SF

Retail Space Available For Rent

Single tenant retail space available, approximately 1,540 square feet.

706 N East St, Frederick, MD 21701
View details
Downtown Frederick Retail Space Available
$3,010 /Mo
2,094 SF

Downtown Frederick Retail Space Available

Retail space in downtown Frederick with onsite parking.

54 E Patrick St, Frederick, MD
View details
Retail Space in Growing Frederick
Contact for pricing
4,700 SF

Retail Space in Growing Frederick

Retail space available in Frederick, Maryland's growing city.

403-419 S Jefferson St, Frederick, MD
View details
Upscale Shopping Center Space
Contact for pricing
2,097 SF

Upscale Shopping Center Space

Retail space in affluent residential community near Rte. 270.

3501 John Simmons St, Frederick, MD
View details
Retail Space in Key Plaza
$22 SF/Yr
10,624 SF

Retail Space in Key Plaza

Mini-anchor space available in Key Plaza, Frederick, MD.

5600 Urbana Pike, Frederick, MD
View details
Frederick Retail Shopping Center Space
Contact for pricing
21,262 SF

Frederick Retail Shopping Center Space

Retail space available in Frederick, Maryland shopping center.

5213-5227 Presidents Court, Frederick, MD
View details
Premier Lifestyle Center Retail Space
Contact for pricing
2,024 SF

Premier Lifestyle Center Retail Space

Retail space available in Frederick County's premier lifestyle center.

5205-5253 Buckeystown Pike, Frederick, MD
View details
Flex Space in Biotech Hub
Contact for pricing
21,200 SF

Flex Space in Biotech Hub

Flex/R&D space in Frederick County's premier biotech hub.

432 Mohican Dr, Frederick, MD
View details
Flex/R&D Space in Biotech Hub
Contact for pricing
2,900 SF

Flex/R&D Space in Biotech Hub

Flex/R&D space in Frederick's premier biotech hub.

8106 E Church St, Frederick, MD
View details
Retail Space in Urbana Center
Contact for pricing
5,546 SF

Retail Space in Urbana Center

Retail space available in high-volume, grocery-anchored shopping center.

3510 Sugarloaf Pkwy, Frederick, MD
View details
Flex Space in Biotech Hub
Contact for pricing
5,500 SF

Flex Space in Biotech Hub

Flex/R&D space in Frederick's EastPark business community.

801 East Church St, Frederick, MD
View details
Urbana Pike Retail/Office Space
$5,935 /Mo

Urbana Pike Retail/Office Space

Retail and office suites available for lease in Frederick, MD.

3535 URBANA Pike unit: 101, Frederick, MD 21704
View details
Flex/R&D Space in Biotech Hub
Contact for pricing
2,325 SF

Flex/R&D Space in Biotech Hub

Flex/R&D space in Frederick's dynamic EastPark business community.

Schifferstadt Blvd, Frederick, MD
View details
Retail Space in Frederick, Maryland
Contact for pricing
1,375 SF

Retail Space in Frederick, Maryland

Retail space for lease in a neighborhood shopping center.

1700 Kingfisher Dr, Frederick, MD
View details
Retail Space in Frederick Mall
$12 SF/Yr

Retail Space in Frederick Mall

Retail space available in Frederick shopping mall near major retailers.

1301 W Patrick St Ste 132, Frederick, MD 21702
View details
Retail Space For Rent
Contact for pricing
120,437 SF

Retail Space For Rent

Single tenant retail space available for lease.

5500 Buckeystown Pike, Frederick, MD 21703
View details

Frederick, MD Retail properties & Spaces Leasing Opportunities Market Analysis

Explore Retail properties & Spaces leasing options in Frederick, MD with 52 listings featured on our commercial real estate exchange. The current inventory includes 14,111,375,537 square feet of properties with an estimated lease value of $121 SF/Yr.

Estimated lease rates for Retail properties & Spaces in Frederick, MD begin at $2 SF/Yr, with an average of $17 SF/Yr and extend to $37 SF/Yr.
List
Map