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    Owensboro, KY Office Space for Lease

    14 results
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    Professional Office Space Available
    Contact for pricing
    1,107 SF

    Professional Office Space Available

    4531 State Route 54, Owensboro, KY 42303

    Prime office space with high traffic count in Owensboro, KY.

    • Prime location on Hwy 54 behind Ritzy's with high traffic count
    • 1107 sqft professional office space
    • Four private offices with option for a fifth
    • Handicap‑accessible bathroom
    • Lease payment includes taxes and insurance
    Updated: Mar 24, 2025
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    Downtown Owensboro Office Space Available
    $2,700 / Mo
    1,747 SF

    Downtown Owensboro Office Space Available

    608 Frederica St 100-B, Owensboro, KY 42301

    Turn-key professional office space in downtown Owensboro for lease.

    • Turn‑key professional office space ready for immediate occupancy.
    • Prime downtown Owensboro location at 608 Frederica Street.
    • Approximately 1,750 sq. ft. of office space.
    • Floor plan includes up to 8 private offices.
    • Includes common areas and restrooms.
    Updated: Sep 16, 2025
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    Prime Office in Business District
    $3,893 / Mo
    2,920 SF

    Prime Office in Business District

    Well-maintained office space in a high-traffic business district.

    2856 Farrell Cres, Owensboro, KY 42301
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    Office Space on Frederica Street
    Contact for pricing
    7,385 SF

    Office Space on Frederica Street

    Office spaces in vibrant location near cultural and shopping districts.

    600 Frederica St, Owensboro, KY 42301
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    Centrally Located Office Space
    $3,126 / Mo

    Centrally Located Office Space

    1,876 sq. ft. office space for lease.

    1302 Frederica St, Owensboro, KY 42301
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    Spacious Commercial Office For Lease
    $2,500 / Mo
    2,958 SF

    Spacious Commercial Office For Lease

    Versatile commercial space with room for 8-10 private offices.

    2816 Veach Rd, Owensboro, KY 42303
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    Downtown Owensboro Office Space
    $18 SF/Yr
    68,250 SF

    Downtown Owensboro Office Space

    Class A Office, Retail & Restaurant Space Available

    234 Frederica St, Owensboro, KY 42301
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    Turn-Key Office Space Available
    $17 SF/Yr
    1,400 SF

    Turn-Key Office Space Available

    Ready-to-occupy office space with reception, offices, restrooms, and workstations.

    3211 Frederica St, Owensboro, KY 42301
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    Versatile Commercial Space in Owensboro
    $22 SF/Yr
    5,688 SF

    Versatile Commercial Space in Owensboro

    Adaptable commercial space suitable for medical or other businesses.

    1921 Leitchfield Rd, Owensboro, KY 42303
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    Medical/Office Space Near Hospital
    $27 SF/Yr
    51,139 SF

    Medical/Office Space Near Hospital

    Proposed medical/office building across from Owensboro Medical Health Systems.

    3808 Vincent Station Dr, Owensboro, KY 42303
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    Updated Office Space in Owensboro
    $595 / Mo
    1,120 SF

    Updated Office Space in Owensboro

    Prime location with updated interior and flexible lease options.

    922 Triplett St, Owensboro, KY 42303
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    Move-in Ready Medical Office Space
    $20 SF/Yr
    19,970 SF

    Move-in Ready Medical Office Space

    Versatile medical office space for lease in Owensboro, KY.

    2831 New Hartford Rd, Owensboro, KY 42303
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    Office/Warehouse Space Available Soon
    $8 SF/Yr
    10,000 SF

    Office/Warehouse Space Available Soon

    Office/warehouse suitable for manufacturing, construction, or supply companies.

    5026-5056 Downwind Dr, Owensboro, KY
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    Furnished Office Space Available
    $510 / Mo
    190 SF

    Furnished Office Space Available

    Furnished office space with included amenities for rent.

    725 Harvard Dr, Owensboro, KY 42301
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    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 14 Active listings in Owensboro, KY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Office space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Historic Downtown Newburgh Office Space
    $1,250 / Mo
    1,440 SF

    Historic Downtown Newburgh Office Space

    Office space in historic Newburgh, Indiana, near the Ohio River.

    107 State St, Newburgh, IN 47630
    View details
    Customizable Office Space in Newburgh
    $2,333 / Mo
    3,550 SF

    Customizable Office Space in Newburgh

    2,000 SF customizable office space in established Newburgh commercial area.

    5055 S Newburgh Plz Dr, Newburgh, IN 47630
    View details
    Tenant-Ready Office Space Available
    $11,500 / Mo
    6,100 SF

    Tenant-Ready Office Space Available

    6,100 SF commercial space ideal for professional or medical use.

    7145 E Virginia St, Evansville, IN 47715
    View details
    Remodeled Office Space For Rent
    $1,125 / Mo
    800 SF

    Remodeled Office Space For Rent

    Newly remodeled office space with utilities included near Washington Square.

    5011 Washington Ave, Evansville, IN 47715
    View details

    Explore Similar Spaces for Sale in Owensboro, KY

    Consider Similar Space for Sale. We found 2 Spaces in Nearby Locations matching your search parameters.

    Downtown Investment Property with Multiple Streams
    $1,350,000

    Downtown Investment Property with Multiple Streams

    Turnkey bar, office space, and luxury apartment in Owensboro.

    119 East 2Nd St, Owensboro, KY 42303
    View details
    Remodeled Commercial Building in Owensboro
    $419,900

    Remodeled Commercial Building in Owensboro

    High-visibility, remodeled commercial building suitable for retail, office, or restaurant.

    2219 Frederica St, Owensboro, KY 42301
    View details

    Owensboro, KY Office space Leasing Opportunities Market Analysis

    Explore Office space leasing options in Owensboro, KY with 16 listings featured on our commercial real estate exchange. The current inventory includes 7,280,792,640 square feet of properties with an estimated lease value of $205 SF/Yr.

    Estimated lease rates for Office space in Owensboro, KY begin at $6 SF/Yr, with an average of $17 SF/Yr and extend to $32 SF/Yr.
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    Popular Searches in Owensboro, KY

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    Most Searched ZIP Codes in Owensboro, KY

    • 42301
    • 42303

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