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Brazoria County, TX Office Properties & Spaces for Sale

27 results
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Medical Office Near CHI Hospital
Contact for pricing
1,493 SF

Medical Office Near CHI Hospital

215 S Oak Dr, Lake Jackson, TX 77566

Move-in ready medical office suite near CHI St. Luke's Hospital.

  • Prime Location: Moments from CHI St. Luke's Health‑Brazosport Hospital.
  • Move‑in Ready: Functional and welcoming layout ideal for healthcare providers.
  • Efficient Layout: Features a spacious lobby, reception area, front office, and four exam rooms.
  • Private Physician's Office: Dedicated space for consultations or administrative work.
  • Convenient Amenities: Includes two restrooms for staff and patients.
Updated: Dec 4, 2025
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Move-in Ready Medical Office Suite
Contact for pricing
1,954 SF

Move-in Ready Medical Office Suite

215 S Oak Dr, Lake Jackson, TX 77566

Versatile medical office near CHI St. Luke's Health-Brazosport Hospital.

  • Prime Location: Minutes from CHI St. Luke's Health‑Brazosport Hospital.
  • Move‑in Ready: Well‑designed, versatile layout suitable for various healthcare specialties.
  • Functional Layout: Includes a comfortable lobby, efficient front office, and six private office/exam rooms.
  • Staff Amenities: Features a spacious break room with ample room and storage.
  • Clinical Support: Two stations with sink access for clinical and sanitation needs.
Updated: Dec 4, 2025
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Angleton Commercial Building For Sale
$525,000
5,000 SF

Angleton Commercial Building For Sale

Multi-suite commercial building in Angleton, TX, suitable for various purposes.

105 E Wilkins St, Angleton, TX 77515
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Angleton Commercial Property For Sale
$300,000
8,088 SF

Angleton Commercial Property For Sale

Versatile commercial building in Angleton, TX, suitable for various operations.

611 N Velasco St, Angleton, TX 77515
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Sweeny TX Commercial Office Space
Pending
$275,000
3,200 SF

Sweeny TX Commercial Office Space

3200 sq ft office space with multiple rooms in Sweeny.

206 N Mckinney St, Sweeny, TX 77480
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Angleton Commercial Flex Space Available
Contact for pricing
1,800 SF

Angleton Commercial Flex Space Available

Commercial flex space featuring office, bathroom, and roll-up doors.

129 N Front St, Angleton, TX 77515
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Sweeny, TX Commercial Building
$325,000
2,093 SF

Sweeny, TX Commercial Building

Commercial building on a corner lot with offices and parking.

307 E 2Nd St, Sweeny, TX 77480
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Angleton Mixed-Use Commercial Property
$399,000

Angleton Mixed-Use Commercial Property

High-traffic corner lot, diverse uses.

120 Mulberry St, Angleton, TX 77515
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Tranquility Center: Pearland, TX
$11,900,000
39,065 SF

Tranquility Center: Pearland, TX

Multi-tenant office complex, high occupancy.

7918 Broadway St, Pearland, TX 77581
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Angleton Mixed-Use Investment Opportunity
$680,000
3,200 SF

Angleton Mixed-Use Investment Opportunity

High-NOI, Creative Office & Warehouse

130 County Road 605C, Angleton, TX 77515
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Historic Alvin Mixed-Use Building
$1,994,000
9,297 SF

Historic Alvin Mixed-Use Building

Downtown Alvin investment opportunity. High NOI potential.

102 Sealy St, Alvin, TX 77511
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Prime Clute Mixed-Use Investment
$575,000
3,125 SF

Prime Clute Mixed-Use Investment

Texas Office/Retail Space - $575K

5107 Highway 288B, Richwood, TX 77531
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Downtown West Columbia Mixed-Use
$379,900
2,034 SF

Downtown West Columbia Mixed-Use

Prime Hwy 35 location; leased retail/office.

201 Brazos Ave, West Columbia, TX 77486
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Downtown Alvin Creative Space
$550,000
5,466 SF

Downtown Alvin Creative Space

Historic charm, modern office, 5,466 sq ft.

415 Gordon St, Alvin, TX 77511
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Mustang Bayou Plaza: Alvin, TX
$2,000,000
5,824 SF

Mustang Bayou Plaza: Alvin, TX

Mixed-use property; prime Alvin location.

824 Adoue St, Alvin, TX 77511
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Pearland Office Building Investment
Contact for pricing
6,058 SF

Pearland Office Building Investment

6,058 SF, 100% Occupied, Strong Tenant

2618 Broadway St, Pearland, TX 77581
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Hwy 36 Office Space for Sale
$375,000
2,600 SF

Hwy 36 Office Space for Sale

Prime West Columbia Office: High Visibility, Move-In Ready

211 Columbia Dr, West Columbia, TX 77486
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Multi-Use Property on SH-36
$199,000
1,785 SF

Multi-Use Property on SH-36

Retail, commercial, or office property with frontage to SH-36.

424 N Brks St, Brazoria, TX
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Highway 36 Commercial Opportunity
$495,000
2,000 SF

Highway 36 Commercial Opportunity

2,000 sqft office with warehouse and laydown yard.

206 S Columbia Dr, West Columbia, TX 77486
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Remodeled Freeport Commercial Building For Sale
$249,900
1,976 SF

Remodeled Freeport Commercial Building For Sale

Remodeled commercial building near Highway 288 and Nolan Ryan Freeway.

1301 Ave N, Freeport, TX
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Move-in Ready Class A Office
$375,000
1,250 SF

Move-in Ready Class A Office

Class A office suite in Pearland's Shadow Creek corridor.

11960 Broadway St, Pearland, TX 77584
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New Commercial Warehouse with Office
$399,900

New Commercial Warehouse with Office

Modern warehouse with office space on a large lot.

19650 Webb Rd, Alvin, TX 77511
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Alvin Retail/Office Opportunity
$398,500
1,750 SF

Alvin Retail/Office Opportunity

1,750 SF brick building on a 6,250 SF corner lot.

104 S Hood St, Alvin, TX 77511
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Adaptable Office Space For Sale
$375,000
2,649 SF

Adaptable Office Space For Sale

Office space with highway frontage, multiple rooms, and covered parking.

211 N Columbia Dr, West Columbia, TX 77486
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Brazoria County, TX Office Properties & Spaces Investment Opportunities Market Analysis

Explore 788 office properties & spaces for sale in Brazoria County, TX, showcased through 27 active listings on our real estate platform. These investment opportunities span a total of 17,951,948 square feet of properties for sale, with an estimated market value of $138,024,000.

Prices for office spaces in Brazoria County, TX start at $80,000, averaging $354,817, and reaching up to $11,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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