Hannibal, MO Office properties & Spaces for sale

Historic Prairie-Style Office/Residence Opportunity

$245,000

2,590 SF

Historic Prairie-Style Office/Residence Opportunity

1001 Center St, Hannibal, MO 63401

Historic 2,590 SF Prairie-style home with office potential in Hannibal, MO.

Historically significant Prairie‑style home (Dulany Mahan House) built in 1913.
Spacious 2,590 sq ft of living space with 4 bedrooms and 2.5 baths.
Original architectural details including a beautiful staircase, hardwood flooring, high ceilings, transom windows, and a sleeping porch.
Wraparound enclosed porch offering flexible use as office space or conversion to living area.
Large living room with a fireplace and a butler’s pantry.

Updated: Jan 23

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Hannibal Commercial Building on St. Mary's

$309,000

8,170 SF

Hannibal Commercial Building on St. Mary's

2903 Saint Marys Ave, Hannibal, MO 63401

Well-maintained commercial building with office/retail space and ample parking.

High visibility location on St. Mary's Ave, near McMaster's traffic.
Boasting over 4,000 sqft of finished office/retail space.
Additional 4,000+ sqft basement for storage or expansion with garage door access.
Two separate office suites with independent access.
Private concrete parking pad with ample parking spots, plus additional rear parking.

Updated: Nov 18, 2025

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Downtown Hannibal Commercial Building For Sale

$239,000

11,592 SF

Downtown Hannibal Commercial Building For Sale

Three-story commercial building with immediate income in downtown Hannibal.

302-304 Broadway, Hannibal, MO 63401

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Updated Commercial Building with Billboard

$599,000

4,336 SF

Updated Commercial Building with Billboard

High-visibility commercial building with income potential in Hannibal, Missouri.

1329 Broadway, Hannibal, MO 63401

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$1,750,000

24,030 SF

Versatile Building in Hannibal, MO

24,030 SF building with flexible space and ample parking.

3201 Palmyra Rd, Hannibal, MO 63401

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Historic Hannibal Restaurant & Apartment

$350,000

0.07 Acres

Historic Hannibal Restaurant & Apartment

Turnkey restaurant, furnished apartment, prime location.

207 Main St, Hannibal, MO 63401

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1.88 Acres

Hannibal Executive Office Building

Prime Hannibal location, 1.88 acres.

3651 Stardust Dr, Hannibal, MO 63401

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Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 7 Active listings in Hannibal, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 1 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

$1,399,999

42,000 SF

Versatile Mixed-Use Commercial Property

Multi-use property with warehouse, office, retail, and apartments.

301 S 7Th St, Quincy, IL 62301

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21,140 SF

Quincy Riverfront Mixed-Use

Prime location, versatile space, stunning views.

138 Front St, Quincy, IL 62301

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Expansive Commercial Building on Large Lot

$375,000

8,000 SF

Expansive Commercial Building on Large Lot

8,000 sq ft building on 1.94 acres for sale.

3001 W Lafayette Ave, Jacksonville, IL 62650

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Spacious Commercial Building on Large Lot

$375,000

1.94 Acres

Spacious Commercial Building on Large Lot

8,000 sq ft building on 1.94 acres for sale.

3001 W Lafayette Ave, Jacksonville, IL 62650

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Explore Off-Market Properties in Hannibal, MO

Consider similar Off-Market properties in Hannibal, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

800 Broadway St

Distribution properties

Value Estimation by Request

800 Broadway St, Hannibal, MO 63401

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Hannibal, MO Office Properties & Spaces Investment Opportunities Market Analysis

Explore 8 office properties & spaces for sale in Hannibal, MO, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 421,530 square feet of properties for sale, with an estimated market value of $3,492,000.

Sale prices for office spaces in Hannibal, MO start at $239,000, averaging $582,000, and reaching up to $1,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Hannibal, MO Office Properties & Spaces for Sale

Historic Prairie-Style Office/Residence Opportunity

Historic 2,590 SF Prairie-style home with office potential in Hannibal, MO.

Hannibal Commercial Building on St. Mary's

Well-maintained commercial building with office/retail space and ample parking.

Downtown Hannibal Commercial Building For Sale