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    Winston-Salem, NC Office Spaces for Lease

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    Winston Salem, NC Kernersville, NC Rural Hall, NC
    46 results
    NC, Winston-Salem - W Third St
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    Versatile Commercial Space Near Clemmons
    Contact for pricing
    7,500 SF
    Versatile Commercial Space Near Clemmons

    6206 Hackers Bend Court, Winston-salem, NC 27103

    Industrial-zoned commercial space with flexible layout and convenient location.
    • Industrial zoning and versatile single‑level commercial space suitable for various business needs
    • Convenient location near Interstate 40, providing easy access
    • Equipped with two drive‑in doors and 220V power, ideal for automotive or similar operations
    • Includes a reception area, private offices, restrooms, and expansive open space
    • Dedicated parking spaces available
    Updated: Feb 13
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    St. George Square
    $129-$5,544/Mo
    St. George Square

    615 St. George Sq Ct, Unit 300, Winston-salem, NC 27103

    Discover many ways to work your way in St. George Square
    • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
    • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
    • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
    • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
    • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
    Updated: Feb 23
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    First-Floor Office Suite For Rent
    $25 SF/Yr
    2,373 SF
    First-Floor Office Suite For Rent

    Well-appointed office suite suitable for professional or medical use.

    1598 Westbrook Plaza Dr, Winston-salem, NC

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    Retail/Office Space Available For Lease
    $18 SF/Yr
    9,253 SF
    Retail/Office Space Available For Lease

    9294 SF retail or office space available October 1, 2025.

    545 Power Plant Cir, Winston-salem, NC

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    Stratford Road Office Space Available
    $21 SF/Yr
    15,000 SF
    Stratford Road Office Space Available

    Office spaces available for lease on Stratford Road.

    514 S Stratford Rd, Winston-salem, NC

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    Class A Office Space Available
    $20 SF/Yr
    1,345 SF
    Class A Office Space Available

    Class A office space with extensive window areas and parking.

    1605 Westbrook Plaza Dr, Winston-salem, NC

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    Medical/Office Space For Lease
    $17 SF/Yr
    5,000 SF
    Medical/Office Space For Lease

    Medical/Office space available for lease near hospitals and major retail.

    150 Charlois Blvd, Winston-salem, NC

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    Class A Office Space Available
    Contact for pricing
    218,488 SF
    Class A Office Space Available

    Class A office tower with unparalleled amenities in Winston-Salem.

    100 North Main Street, Winston-salem, NC 27101

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    Suburban Office Space Available
    $1,450/Mo
    521 SF
    Suburban Office Space Available

    Office space for rent in convenient location near I-40.

    3410 Healy Dr, Winston-salem, NC

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    Winston-Salem Flex Space Available
    $15 SF/Yr
    15,600 SF
    Winston-Salem Flex Space Available

    15,600 SF flex space with office and parking.

    3064 Salem Industrial Dr, Winston-salem, NC

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    Historic Building Retail/Office Space
    $19 SF/Yr
    7,400 SF
    Historic Building Retail/Office Space

    Redeveloped historic building offering retail and office space for lease.

    500 W 4th St, Winston-salem, NC

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    Two-Story Office Building For Rent
    Contact for pricing
    1,932 SF
    Two-Story Office Building For Rent

    Two-story office building with on-site parking in convenient location.

    3288 Robinhood Road, Winston-salem, NC 27106

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    Office Space Near Retail Market
    $950/Mo
    856 SF
    Office Space Near Retail Market

    Office space in Winston-Salem's prime retail location.

    1495 Rymco Dr, Winston-salem, NC

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    Hanes Mall Corridor Office Sublease
    Contact for pricing
    101,555 SF
    Hanes Mall Corridor Office Sublease

    Office sublease in desirable Hanes Mall corridor with easy access.

    799 Hanes Mall Boulevard, Winston-salem, NC 27103

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    Move-in Ready Medical Office Space
    $25 SF/Yr
    3,864 SF
    Move-in Ready Medical Office Space

    First floor medical office in convenient location near I-40.

    725 Highland Oaks Dr, Winston-salem, NC

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    Downtown Winston-Salem Office Space
    Contact for pricing
    4,000 SF
    Downtown Winston-Salem Office Space

    Prime office space in Winston-Salem's Central Business District.

    500 West 5th Street, Winston-salem, NC 27101

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    Renovated Office Space Available
    $1,000/Mo
    1,000 SF
    Renovated Office Space Available

    Second-floor office space with recent upgrades in Winston-Salem.

    1365 Westgate Center Dr, Winston-salem, NC

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    Two-Story Office Building For Rent
    Contact for pricing
    5,842 SF
    Two-Story Office Building For Rent

    Two-story office building near I-40 and Hwy 421.

    4505 Country Club Road, Winston-salem, NC 27104

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    Winston-Salem Industrial Space Available
    $9 SF/Yr
    15,000 SF
    Winston-Salem Industrial Space Available

    15,000 SF industrial space featuring warehouse and office areas.

    2534 Empire Dr, Winston-salem, NC

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    Well-Maintained Office Space Available
    $2,250/Mo
    1,660 SF
    Well-Maintained Office Space Available

    Office space near retail corridor with significant natural light.

    1321 Westbrook Plaza Dr, Winston-salem, NC

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    Renovated Office Building For Rent
    Contact for pricing
    1,474 SF
    Renovated Office Building For Rent

    Completely renovated two-story office building in Winston Salem CBD.

    601 West 4th Street, Winston-salem, NC 27101

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    Retail/Medical Space on Hanes Mall
    Contact for pricing
    2,783 SF
    Retail/Medical Space on Hanes Mall

    2,783 SF space suitable for retail or medical office.

    1255-1287 Creekshire Way, Winston-salem, NC

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    Winston-Salem Office Space Available
    $325/Mo
    302 SF
    Winston-Salem Office Space Available

    Office space for rent in a prime location.

    1348 Westgate Center Dr, Winston-salem, NC

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    Winston-Salem, NC Office Spaces Leasing Opportunities Market Analysis

    Explore Office Spaces leasing options in Winston-Salem, NC with 46 listings featured on our commercial real estate exchange. The current inventory includes 106,565 square feet of properties with an estimated lease value of $637 /Mo.

    Estimated lease rates for Office Spaces in Winston-Salem, NC begin at $9 SF/Yr, with an average of $30 SF/Yr and extend to $275 SF/Yr.
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    Most Searched ZIP Codes in Winston-Salem, NC

    • 27101
    • 27103
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