Sign Up Successful!
You now have access to more from Realmo!
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Prince Frederick, MD Office Properties & Spaces for Lease

    10 results
    List
    Map
    Prince Frederick Office Suite For Lease
    $1,100 / Mo
    54,450 SF

    Prince Frederick Office Suite For Lease

    65 Duke St, Prince Frederick, MD 20678

    Corner office suite in a convenient Prince Frederick location.

    • Prime location in Prince Frederick's convenient office area.
    • Corner suite with large waiting area and two private offices.
    • Newly installed vinyl plank flooring and fresh paint throughout the suite.
    • Recently updated common areas including lobby and bathrooms.
    • Rent price includes monthly CAM fee.
    Updated: Nov 13, 2025
    View details
    Prince Frederick Main Level Office
    $2,400 / Mo

    Prince Frederick Main Level Office

    85 Sherry Ln, Prince Frederick, MD 20678

    Main level office space in a professional Prince Frederick building.

    • Ready for immediate occupancy with 1190 sq ft of main‑level office space.
    • Rent includes common area maintenance, water/sewer, real estate taxes, trash, and snow removal.
    • Convenient location in Prince Frederick with quick access to Route 4, courthouse, hospital, and services.
    • Features a conference room, three offices, bathroom, and kitchenette.
    • Secure access with keyed foyer entry, coded office door locks, and an exterior side entrance.
    Updated: Aug 3, 2025
    View details
    Prince Frederick Office/Retail Space
    $1,500 / Mo

    Prince Frederick Office/Retail Space

    Office or retail space available for lease in Prince Frederick.

    101 Skipjack Rd, Prince Frederick, MD 20678
    View details
    Built-Out Office Building For Rent
    $5,590 / Mo

    Built-Out Office Building For Rent

    Two-story office building with private offices, kitchen, and elevator.

    493 Prince Frederick Blvd, Prince Frederick, MD 20678
    View details
    Main Street Medical Office Space
    $20 SF/Yr
    7,824 SF

    Main Street Medical Office Space

    Prince Frederick, MD Medical Office Suites Available

    141 Main St, Prince Frederick, MD 20678
    View details
    Prince Frederick Medical Office Space
    Contact for pricing
    5,707 SF

    Prince Frederick Medical Office Space

    Prime Calvert County medical office suites available.

    815 Prince Frederick Blvd, Prince Frederick, MD 20678
    View details
    Professional Building Shell Space Available
    $1,060 / Mo

    Professional Building Shell Space Available

    1,270 sq ft vacant shell space on 2nd floor.

    489 202 Main St St, Prince Frederick, MD 20678
    View details
    Office Space on Main Street
    $1,500 / Mo

    Office Space on Main Street

    Office space for rent with frontage on Main Street.

    165 Main St, Prince Frederick, MD 20678
    View details
    Professional Office Space Available
    $1,060 / Mo

    Professional Office Space Available

    1,270 sq ft vacant shell office space for rent.

    489 202 Main St St, Prince Frederick, MD 20678
    View details
    Built-Out Office Space Available
    $5,590 / Mo

    Built-Out Office Space Available

    Two-story office building with private offices, kitchen, and elevator.

    493 And 201, Prince Frederick, MD 20678
    View details
    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 10 Active listings in Prince Frederick, MD, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Explore Office Properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Route 4 Office Space Available
    $3,325 / Mo

    Route 4 Office Space Available

    2100 sqft office space on Route 4 with high visibility.

    2425 Solomons Island Rd, Huntingtown, MD 20639
    View details
    Huntingtown Professional/Medical Office Space
    $1,350 / Mo
    119,354 SF

    Huntingtown Professional/Medical Office Space

    Professional/Medical office space in Huntingtown, MD, with natural light.

    2555 Solomons Island Rd, Huntingtown, MD 20639
    View details
    Renovated Office Space For Lease
    $22 SF/Yr

    Renovated Office Space For Lease

    2,800 sq ft renovated office space in high-traffic location.

    28265 Three Notch Rd, Mechanicsville, MD 20659
    View details
    Mechanicsville Office Space For Rent
    $1,950 / Mo

    Mechanicsville Office Space For Rent

    Office space for rent in the heart of Mechanicsville.

    29015 Three Notch Rd, Mechanicsville, MD 20659
    View details

    Explore Similar Spaces for Sale in Prince Frederick, MD

    Consider Similar Space for Sale. We found 3 Spaces in Nearby Locations matching your search parameters.

    Medical Office Condo For Sale
    Contact for pricing
    21,532 SF

    Medical Office Condo For Sale

    Medical office condo across from Calvert Health Medical Center.

    125 Stoakley Rd, Prince Frederick, MD 20678
    View details
    Professional Office Building For Sale
    $1,900,000

    Professional Office Building For Sale

    Fully leased professional office building near hospital, shopping, and restaurants.

    1020 Prince Frederick Blvd, Prince Frederick, MD 20678
    View details
    Prince Frederick Office Complex
    $1,900,000
    10,000 SF

    Prince Frederick Office Complex

    Prime Town Center location, 9-tenant office building.

    1020 Prince Frederick Blvd, Prince Frederick, MD 20678
    View details

    Prince Frederick, MD Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Prince Frederick, MD with 13 listings featured on our commercial real estate exchange. The current inventory includes 340,813,440 square feet of properties with an estimated lease value of $20 SF/Yr.

    Estimated lease rates for Office Properties & Spaces in Prince Frederick, MD begin at $20 SF/Yr, with an average of $20 SF/Yr and extend to $20 SF/Yr.
    List
    Map

    Browse Office Properties & Spaces for Lease Near Prince Frederick, MD

    Popular Searches in Prince Frederick, MD

    Most Searched ZIP Codes in Prince Frederick, MD

    • 20678

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.